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Weight training can make a big difference for breast cancer survivors

Weight training can be a big boost to breast cancer survivors who are trying to regain muscle and bone strength lost due to cancer treatment and physical inactivity, says a Florida State University researcher.

1 Oct 2015

Yale ResearchKit app can help assess heart problems in children and young adults

Imagine being able to contribute to research about heart problems affecting children and adults with an iPhone app. That idea is now a reality with today's launch of the Yale Cardiomyopathy Index, an iPhone-based clinical study to better understand quality of life for people ages two to 80 who have or may develop a cardiomyopathy -- an abnormality in the heart muscle.

1 Oct 2015

Research shows why microgravity leads to muscle loss

People can easily feel the presence - or absence - of gravity. Our individual cells actually may be able to sense gravity, too, and that ability could play a role in the loss of muscle that occurs when humans spend time in space.

1 Oct 2015

OncoGenex meets target enrollment in apatorsen Phase 2 trial

OncoGenex Pharmaceuticals, Inc. announced today that Borealis-2, an investigator-sponsored, randomized Phase 2 trial, has met its target enrollment of 200 patients. Designed to evaluate apatorsen in combination with docetaxel in patients with advanced or metastatic bladder cancer who have disease progression following first-line platinum-based chemotherapy, Borealis-2 is sponsored by Hoosier Oncology Group and is being conducted at 27 sites across the United States.

30 Sep 2015

AMO Pharma raises $25 million in private equity financing

AMO Pharma Limited, a privately held biopharmaceutical company focusing on debilitating diseases with limited or no treatment options, announced today that the company has raised $25 million in private equity financing from Woodford Investment Management.

30 Sep 2015

Survey: One-third of US women use compounded hormones at menopause

A third of US women who take hormones at menopause are using compounded hormones, shows a new national survey. These women commonly--and mistakenly--think these hormones are safer and offer more benefits than FDA-approved therapies.

30 Sep 2015

New gene therapy approach to treating DMD reduces symptoms, extends life span in mouse model

A gene therapy approach to treating the progressive muscle wasting disorder Duchenne muscular dystrophy (DMD) that does not replace the mutated DMD gene but instead delivers the gene for ITGA7, a protein in skeletal muscle, led to reduced symptoms and significantly extended life span in a mouse model of severe DMD. Over-expression of ITGA7 did not elicit an immune reaction, further supporting its potential as a novel treatment for DMD, according to a new study published in Human Gene Therapy, a peer-reviewed journal from Mary Ann Liebert, Inc., publishers.

30 Sep 2015

Predicting better immunotherapy response, neurological outcomes in adults with autoimmune cerebellar ataxia

While autoimmune cerebellar ataxia (a loss of muscle control coordination) can lead to severe disability with some patients becoming wheelchair-bound, there are factors that may help predict better immunotherapy response, according to the Mayo Clinic study published by JAMA Neurology.

30 Sep 2015

Researchers unlock structural details of key protein to treat neuromuscular disease

Researchers at Rice University and Baylor College of Medicine have unlocked the structural details of a protein seen as key to treating a neuromuscular disease.

30 Sep 2015

Researchers develop methodology to monitor changes in DNA methylation patterns in individual cells

Whitehead Institute researchers have developed a methodology to monitor changes in DNA methylation over time in individual cells.

26 Sep 2015

Re-engineering the brain to perceive food differently

Can we make people healthier by tricking the brain into thinking broccoli tastes like chocolate? A group of internationally acclaimed chefs, bench neuroscientists, food scientists and clinical neurologists are confident that they can.

26 Sep 2015

Scripps becomes first health care provider in San Diego County to implant Evera MRI SureScan ICD System

Scripps Health is the first health care provider in San Diego County to use the only implantable cardioverter defibrillator (ICD) device approved for use with magnetic resonance imaging (MRI) scans.

26 Sep 2015

Inflammatory response could be key link between dietary fats and obesity-related diseases

An enhanced inflammatory response could be the key link between high saturated fat intake - a recognized risk factor for obesity-related disorders - and the development of diseases like type 2 diabetes and atherosclerosis.

26 Sep 2015

New study on deep-diving whales may help researchers create synthetic blood for human trauma patients

The ultra-stable properties of the proteins that allow deep-diving whales to remain active while holding their breath for up to two hours could help Rice University biochemist John Olson and his colleagues finish a 20-year quest to create lifesaving synthetic blood for human trauma patients.

26 Sep 2015

Amgen gets positive CHMP opinions for Kyprolis (carfilzomib) and BLINCYTO (blinatumomab)

"We are pleased to receive positive CHMP opinions for Kyprolis and BLINCYTO as this is an important step in providing new treatment options for patients in Europe with rare forms of cancer," said Sean E. Harper, M.D., executive vice president of Research and Development at Amgen.

25 Sep 2015

Novel brain-computer interface technology allows paralyzed man to walk

Novel brain-computer interface technology created by University of California, Irvine researchers has allowed a paraplegic man to walk for a short distance.

25 Sep 2015

Research highlights potential new treatment strategy for degenerative diseases

St. Jude Children's Research Hospital scientists have discovered evidence of a mechanism at the heart of amyotrophic lateral sclerosis (ALS) and related degenerative diseases. The research appears in today's edition of the journal Cell and highlights a possible new treatment strategy for the devastating disorders.

25 Sep 2015

HSCI researchers find surprising similarities between SMA and ALS

Harvard Stem Cell Institute researchers studying spinal muscular atrophy (SMA) have found what they term "surprising similarities" between this childhood disorder that attacks motor neurons and amyotrophic lateral sclerosis (ALS), more commonly known as Lou Gehrig's disease.

25 Sep 2015

Sticky, protein-rich gel improves cardiac function after simulated heart attacks

A sticky, protein-rich gel created by Johns Hopkins researchers appears to help stem cells stay on or in rat hearts and restore their metabolism after transplantation, improving cardiac function after simulated heart attacks, according to results of a new study.

25 Sep 2015

TSRI scientists awarded grant from Gates Foundation to develop revolutionary alternative HIV/AIDS vaccine

Scientists from the Florida campus of The Scripps Research Institute have been awarded up to nearly $6 million dollars from the Bill & Melinda Gates Foundation to develop a revolutionary HIV/AIDS alternative vaccine that has demonstrated great potential in animal models.

23 Sep 2015

Muscle News and Research

Weight training can make a big difference for breast cancer survivors

Yale ResearchKit app can help assess heart problems in children and young adults

Research shows why microgravity leads to muscle loss

OncoGenex meets target enrollment in apatorsen Phase 2 trial

AMO Pharma raises $25 million in private equity financing

Survey: One-third of US women use compounded hormones at menopause

New gene therapy approach to treating DMD reduces symptoms, extends life span in mouse model

Predicting better immunotherapy response, neurological outcomes in adults with autoimmune cerebellar ataxia

Researchers unlock structural details of key protein to treat neuromuscular disease

Researchers develop methodology to monitor changes in DNA methylation patterns in individual cells

Re-engineering the brain to perceive food differently

Scripps becomes first health care provider in San Diego County to implant Evera MRI SureScan ICD System

Inflammatory response could be key link between dietary fats and obesity-related diseases

New study on deep-diving whales may help researchers create synthetic blood for human trauma patients

Amgen gets positive CHMP opinions for Kyprolis (carfilzomib) and BLINCYTO (blinatumomab)

Novel brain-computer interface technology allows paralyzed man to walk

Research highlights potential new treatment strategy for degenerative diseases

HSCI researchers find surprising similarities between SMA and ALS

Sticky, protein-rich gel improves cardiac function after simulated heart attacks

TSRI scientists awarded grant from Gates Foundation to develop revolutionary alternative HIV/AIDS vaccine

Event guide: 4th Extra-Hepatic Lipid-Based Nanoparticles Delivery Summit eBook

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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