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Viewpoints: Super committee clock is ticking; replacing CLASS; 'personhood' amendment in Miss.

There are only three weeks left for the Congressional supercommittee to come up with a plan to reduce the federal deficit by at least $1.2 trillion, and there is no sign that the panel is anywhere close to reaching an agreement. Only one side, in fact, seems to be trying - the Democrats - and it is being far too accommodating, given the fierce obstructionism of the other side, the Republicans.

2 Nov 2011

Infinity commences two IPI-145 Phase 1 clinical trials for hematologic malignancies

Infinity Pharmaceuticals, Inc. today announced that it has initiated two Phase 1 clinical trials of IPI-145, a potent, orally available inhibitor of phosphoinositide-3-kinase (PI3K) delta and gamma. These two enzymes are implicated in hematologic cancers as well as a broad range of inflammatory conditions, which are the areas of focus within Infinity's PI3K clinical development program.

31 Oct 2011

Mayo Clinic, Oxford BioMedica collaborate to develop gene therapy for glaucoma

Oxford BioMedica plc, the leading gene-based biopharmaceutical company, today announces that it has entered into a research and development collaboration with Mayo Clinic, Rochester (USA) to develop a novel gene therapy for the treatment of chronic glaucoma.

31 Oct 2011

Floridians say state must be a leader in science and medical research

A majority of Floridians (87%) believe it is important for their state to be a leader in science and medical research, according to a new state poll commissioned by Research!America. The poll also shows that 80% think spending money on scientific research is important for Florida's economy in terms of job creation and incomes.

28 Oct 2011

Manipulating normal bacteria could tackle gum disease

Normal bacteria which live in our mouths provide the catalyst for the development of gum disease, a debilitating condition which leads to painful gums and the loosening of teeth, new research from Queen Mary, University of London has found.

28 Oct 2011

La Jolla Institute becomes 5th participant in novel stem cell research collaboration

The La Jolla Institute for Allergy & Immunology has become the fifth organization in the prestigious Sanford Consortium for Regenerative Medicine, joining colleagues from the Salk Institute for Biological Studies, The Scripps Research Institute, University of California, San Diego and the Sanford-Burnham Medical Research Institute in the first-of-its-kind multi-institutional stem cell research collaboration.

28 Oct 2011

International diabetes researchers to engineer artificial pancreas system

The National Institutes for Health (NIH) have awarded $4.5 million to a group of international diabetes researchers to engineer an artificial pancreas system that will monitor and adapt to the body's complex real-time changes in behavior and physiology.

27 Oct 2011

Super broccoli on the shelves to protect from heart disease

British scientists unveiled a new breed of broccoli that experts say packs heavy on nutritional values. The new broccoli was specially grown to contain two to three times the normal amount of glucoraphanin, a nutrient believed to help ward off heart disease. Glucoraphanin breaks fat down in the body, preventing it from clogging the arteries.

27 Oct 2011

Tiny teeth in tatters

The tiny teeth of Australian toddlers are rotting and dental researchers at the University of Sydney are poised to start a long-term study to find out why.

25 Oct 2011

NHMRC awards $2 million to investigate new therapies for reversing autoimmune disease

Research being undertaken at the University of Adelaide and Women's and Children's Hospital is providing vital clues into the causes of autoimmune diseases which affect millions of people around the world.

24 Oct 2011

FDA approves intraspinal injections in spinal cord stem cell ALS trial

Neuralstem, Inc. updated the progress of its ongoing Phase I safety trial of the company's spinal cord stem cells in the treatment of amyotrophic lateral sclerosis (ALS or Lou Gehrig's disease) at Emory University in Atlanta, Georgia.

24 Oct 2011

Social media moves into medicine

The Mayo Clinic's social media boss explains how the use of these high-tech tools has moved beyond marketing to find a place in medical education and research. Meanwhile, another news report showcases how doctors use email and Skype.

21 Oct 2011

University of Delaware receives DoD grant to create and manage BADER Consortium

The Department of Defense (DoD) Congressionally Directed Medical Research Programs (CDMRP) Peer Reviewed Orthopaedic Research Program (PRORP) has awarded a $19.7 million grant to the University of Delaware to create and manage a consortium that will improve the quality of life for warfighters who suffer significant limb injuries in combat.

20 Oct 2011

Tenofovir gel shows promise against HSV infection

HIV infection is commonly associated with other sexual infections, such as herpes simplex virus (HSV). Infection with HSV facilitates the risk of HIV infection and negatively impacts the clinical course of HIV disease. Therefore, it would be highly beneficial to identify multi-faceted microbicide compounds that are efficient against HIV-1 and other sexually transmitted infections.

20 Oct 2011

Viewpoints: CLASS decision ends fear of government bailout; the strengths and failings of U.S. health care

The problem, as numerous experts warned at the time, was whether the program could be run, as the law required, in a way that made it financially solvent for at least 75 years. The difficulty with the CLASS Act was ensuring that premiums could be set low enough to attract widespread participation but high enough to pay tbenefits. The risk was that the program would attract the sickest participants, who thought they might need its protections, and thereby drive premium prices ever higher in a spiral of dysfunctionhe promised.

19 Oct 2011

With clock ticking, super committee weighs suggestions, battles doubts

Last week the deficit-reduction panel received a slew of recommendations from across Capitol Hill on how to tame the nation's deficit problems. The input evidenced partisan differences and intra-party fissures. All the while, questions persist about the committee's ability to actually reach a deal.

18 Oct 2011

Commercialization strategies for next-generation medicines

The Center for Biotechnology at Stony Brook University, in collaboration with Demy-Colton Life Science Advisors, and key opinion leaders from the biotech and biopharmaceutical industries, academia, medical research foundations, and investment community, has organized a two-day event to forge partnerships to accelerate the development of new treatments for some of the world's most devastating diseases affecting millions.

18 Oct 2011

Stochastic frontier estimation can identify problem of bias in self-reporting

Most people are rather vague when reporting on food and drink consumption, smoking and exercise habits. General practitioners, however, are skilled at interpreting phrases such as "I only have a few drinks rarely...each week" and "I get to the gym regularly" and can estimate based on symptoms and a person's physical appearance just how precise those claims are. However, it is crucial for healthcare research and epidemiology that relies on patient self-reporting that we find a more objective, rather than intuitive, way to identify bias in self-reporting.

18 Oct 2011

New treatment approach for septic Listeria infection

Research underway at the Trudeau Institute could lead to new treatments for people sickened by Listeria and other sepsis-causing bacteria. Dr. Stephen Smiley's laboratory has published a study in the scientific journal Infection and Immunity that supports a new approach to treating these infections.

18 Oct 2011

Omega-3 in fish oil could reduce signs and symptoms of osteoarthritis

New research has shown for the first time that omega-3 in fish oil could "substantially and significantly" reduce the signs and symptoms of osteoarthritis.

18 Oct 2011