Muscle News and Research

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Study demonstrates potential of FCPCs as new source for cartilage regeneration

The self-repair of injured cartilage is difficult for several reasons, foremost of which is the lack of blood supply to the tissue. Therapeutic efforts aimed at cartilage repair are often not optimal. Surgical repair techniques often lead to the formation of fibrocartilage, which is weaker and less durable. Although cell transplantation aimed at cartilage repair has been carried out using mesenchymal stem cells (MSCs), varying outcomes have resulted, despite the propensity of MSCs to proliferate and differentiate.

23 Sep 2015

UCSF researchers successfully separate human muscle stem cells

UC San Francisco researchers have successfully isolated human muscle stem cells and shown that the cells could robustly replicate and repair damaged muscles when grafted onto an injured site. The laboratory finding paves the way for potential treatments for patients with severe muscle injury, paralysis or genetic diseases such as muscular dystrophy.

23 Sep 2015

Endurance training affects how the brain and muscles communicate with each other

Using endurance training or strength and resistance training not only prepares an athlete for different types of sports, they can also change the way the brain and muscles communicate with each other.

21 Sep 2015

New study finds link between maternal protein deficiency during pregnancy and metabolic diseases in offspring

A new study has uncovered the genetic processes that link insufficient protein consumption during pregnancy with the development of muscle problems in mothers and their male offspring.

19 Sep 2015

CardioDx announces national agreement with Quest Diagnostics to expand access to Corus CAD blood test

CardioDx, Inc., a molecular diagnostics company specializing in cardiovascular genomics, today announced a national specimen-draw agreement with Quest Diagnostics DGX, +1.23% the world's leading provider of diagnostic information services, that will expand patient and clinician access to the Corus CAD lab-developed blood test for aiding the assessment of obstructive coronary artery disease (CAD).

From Quest Diagnostics 18 Sep 2015

Amgen, Xencor partner to develop and commercialize new therapeutics for cancer immunotherapy, inflammation

Amgen and Xencor, Inc. announced today that the two companies have entered into a research and license agreement to develop and commercialize novel therapeutics in the areas of cancer immunotherapy and inflammation.

16 Sep 2015

Florida Institute finalizes funding agreement with MYOLYN

The Florida Institute for the Commercialization of Public Research announced today that it has finalized a funding agreement with MYOLYN, a Gainesville-based company with technology licensed from the University of Florida.

15 Sep 2015

Researchers discover new gene that could be a potential therapeutic target for muscle wasting

It is estimated that half of all cancer patients suffer from a muscle wasting syndrome called cachexia. Cancer cachexia impairs quality of life and response to therapy, which increases morbidity and mortality of cancer patients. Currently, there is no approved treatment for muscle wasting but a new study from the Research Institute of the McGill University Health Centre and University of Alberta could be a game changer for patients, improving both quality of life and longevity.

15 Sep 2015

Fusion IONZ’s non-thermal far infrared technology successfully passes board certified clinical trial

Fusion IONZ has successfully commissioned and passed a three phase human clinical trial. This clinical trial was conducted by the Dr. Lisa Tully and the Energy Medicine Research Institute.

15 Sep 2015

Prolonged sitting time, reduced physical activity contribute to non-alcoholic fatty liver disease

Prolonged sitting time as well as reduced physical activity contribute to the prevalence of non-alcoholic fatty liver disease (NAFLD) in a study of middle-aged Koreans.

15 Sep 2015

New strategy improves bone repair by boosting survival rate of transplanted stem cells

Stem cell therapies are often limited by low survival of transplanted stem cells and the lack of precise control over their differentiation into the terminal cell types needed to repair or replace injured tissues. Now, a team led by Wyss Institute Core Faculty member David Mooney, Ph.D., has developed a new strategy - embedding stem cells into porous, transplantable hydrogels - that has experimentally improved bone repair by boosting the survival rate of transplanted stem cells and influencing their cell differentiation.

15 Sep 2015

Better treatment could be on the horizon for Myasthenia Gravis

Myasthenia Gravis (MG) is a debilitating and potentially deadly disease that can afflict anyone, characterized by severe muscle weakness, affecting control of facial expressions, arm and leg movements, chewing, swallowing, coughing and breathing. There is no cure, only treatment.

14 Sep 2015

Researchers link molecular dots between periodontitis and heart disease

Periodontitis is a risk factor for heart disease. Now a team of researchers has shown that a periodontal pathogen causes changes in gene expression that boost inflammation and atherosclerosis in aortic smooth muscle cells. The research is published ahead of print in Infection and Immunity, a journal of the American Society for Microbiology.

14 Sep 2015

Innovative technologies offer hope to people living with chronic pain

More than 100 million people in this country have pain that won't go away. Many of these chronic pain sufferers fail to get relief from pills, shots and even surgery, while others temporarily trade the pain for side effects such as drowsiness or digestive problems.

11 Sep 2015

Older men can benefit from high-intensity training, not older women

The research team observed obese senior males and females 62 and older. The subjects were assigned a regimen of high-intensity exercise that occurred three times per week for six weeks.

11 Sep 2015

New research shows direct evidence of greater mitochondrial damage in Gulf War veterans

One in four Gulf War veterans suffers from Gulf War Illness (GWI). The condition is characterized by unexplainable chronic fatigue, muscle pain and cognitive dysfunction and may be associated with exposure to chemicals, many identified as genotoxins, during deployment.

11 Sep 2015

ACR releases two new publications to improve treatment of polymyalgia rheumatica, gout

The American College of Rheumatology (ACR) has released two new publications - recommendations aimed at improving the treatment of patients with polymyalgia rheumatica (PMR), and new classification criteria for gout.

10 Sep 2015

First patient dosed in long term-safety extension study of Resolaris for adult patients with FSHD

aTyr Pharma, Inc., a biotherapeutics company engaged in the discovery and development of Physiocrine-based therapeutics to address severe rare diseases, today announced that the first patient has been dosed in a newly initiated long term-safety extension study of Resolaris for adult patients with facioscapulohumeral muscular dystrophy (FSHD), a rare and severe genetic myopathy for which there are currently no approved treatments.

10 Sep 2015

Allergan settles patent litigation with Amneal related to NAMENDA XR extended release capsules

Allergan plc, today announced that its subsidiaries Forest Laboratories, LLC and Forest Laboratories Holdings, Ltd., along with Adamas Pharmaceuticals, Inc., have entered into a settlement agreement with Amneal Pharmaceuticals LLC and related companies and subsidiaries.

10 Sep 2015

Study shows external brain stimulation temporarily improves motor symptoms in Parkinson's patients

People with Parkinson's disease (PD) tend to slow down and decrease the intensity of their movements even though many retain the ability to move more quickly and forcefully.

10 Sep 2015

Muscle News and Research

Study demonstrates potential of FCPCs as new source for cartilage regeneration

UCSF researchers successfully separate human muscle stem cells

Endurance training affects how the brain and muscles communicate with each other

New study finds link between maternal protein deficiency during pregnancy and metabolic diseases in offspring

CardioDx announces national agreement with Quest Diagnostics to expand access to Corus CAD blood test

Amgen, Xencor partner to develop and commercialize new therapeutics for cancer immunotherapy, inflammation

Florida Institute finalizes funding agreement with MYOLYN

Researchers discover new gene that could be a potential therapeutic target for muscle wasting

Fusion IONZ’s non-thermal far infrared technology successfully passes board certified clinical trial

Prolonged sitting time, reduced physical activity contribute to non-alcoholic fatty liver disease

New strategy improves bone repair by boosting survival rate of transplanted stem cells

Better treatment could be on the horizon for Myasthenia Gravis

Researchers link molecular dots between periodontitis and heart disease

Innovative technologies offer hope to people living with chronic pain

Older men can benefit from high-intensity training, not older women

New research shows direct evidence of greater mitochondrial damage in Gulf War veterans

ACR releases two new publications to improve treatment of polymyalgia rheumatica, gout

First patient dosed in long term-safety extension study of Resolaris for adult patients with FSHD

Allergan settles patent litigation with Amneal related to NAMENDA XR extended release capsules

Study shows external brain stimulation temporarily improves motor symptoms in Parkinson's patients

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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