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New research explains how large virus shells are formed

A virus, the simplest physical object in biology, consists of a protein shell called the capsid, which protects its nucleic acid genome -- RNA or DNA. The capsid can be cylindrical or conical in shape, but more commonly it assumes an icosahedral structure, like a soccer ball.

5 Nov 2018

Genetic factors linked to obesity may lower metabolic risk

Experts believe that where on the body people store surplus fat, whether round their middle or round the liver, may be genetically determined.

2 Nov 2018

Illumina signs agreement to acquire Pacific Biosciences

Illumina, Inc. and Pacific Biosciences today announced they have signed an agreement for Illumina to acquire Pacific Biosciences at a price of $8.00 per Pacific Biosciences share in an all-cash transaction.

2 Nov 2018

Zinc can protect against oxidative stress when taken along with coffee, tea, and chocolate

Ageing and a low life expectancy are caused, at least partly, by oxidative stress. A team of researchers led by Prof. Dr. Ivana Ivanovi-Burmazovi from the Chair of Bioinorganic Chemistry at Friedrich-Alexander-Universität Erlangen-Nürnberg (FAU), together with researchers from the USA, have discovered that zinc can activate an organic molecule, helping to protect against oxidative stress.

2 Nov 2018

UCLA researchers investigate how a protein factor contributes to cancer cell migration

UCLA researchers have discovered a new protein factor that contributes to a fibroblast cell's ability to migrate to a wound and participate in its healing process. The study's results could help scientists prevent cancer cells from using the same mechanisms to move throughout the body and spread.

1 Nov 2018

Scientists decode the longest ever continuous DNA sequence

Scientists have decoded the longest continuous DNA sequence to date, measuring around 10,000 times longer than normal sequencing reads.

1 Nov 2018

Observing functional changes of cells in blood vessels may help detect early signs of atherosclerosis

A study in mice has shown that it may be possible to detect the early signs of atherosclerosis, which leads to blocked arteries, by looking at how cells in our blood vessels change their function.

1 Nov 2018

Presence of rare mutations indicates increased risk from interval breast cancers

While the presence of common breast cancer mutations was indicative of increased breast cancer risk, the presence of certain rare mutations was indicative of increased risk from interval breast cancers and death.

1 Nov 2018

Repair defect in neurons hints at possible therapy for preventing ALS

Houston Methodist researchers have discovered a repair defect in nerve cells that send messages to the brain, opening the door to a possible therapy for preventing or slowing down ALS.

1 Nov 2018

UC Scientist receives NIH grant for developing new malaria therapeutic strategies

A scientist at the University of California, Riverside, who researches the malaria-causing parasite, Plasmodium falciparum, is the principal investigator, or PI, on two grants from the National Institutes of Health, or NIH, totaling nearly $6.6 million. Funding from each grant is for five years.

1 Nov 2018

UA scientists aim to identify drug targets for rare pediatric cancer

Rhabdomyosarcoma is a rare cancer of the skeletal muscle that primarily affects pediatric patients. After diagnosis, about 3 out of 4 patients are cured with standard treatment. Survival rates drop to 17 percent if the disease comes back (recurs) and to 30 percent if it spreads (metastasizes).

1 Nov 2018

FDA permits marketing of 23andme Personal Genome Service Pharmacogenetic Reports test

Today, the U.S. Food and Drug Administration permitted marketing, with special controls, of the 23andme Personal Genome Service Pharmacogenetic Reports test as a direct-to-consumer test for providing information about genetic variants that may be associated with a patient's ability to metabolize some medications to help inform discussions with a health care provider.

1 Nov 2018

Genetic testing and breakthrough therapies may transform diagnosis, care of neuromuscular disease

A new report funded by the Muscular Dystrophy Association and released by the IQVIA Institute for Human Data Science indicates that genetic testing and breakthrough therapies will transform the diagnosis and care of neuromuscular disease within the next decade.

31 Oct 2018

CRISPR genome editing has foreseeable implications for plastic and reconstructive surgery

The CRISPR genome editing technique promises to be a "transformative leap" in genetic engineering and therapy, affecting almost every area of medicine.

31 Oct 2018

Growth of genomic databases hinders efforts to identify bacteria

There are many ways to slice and dice genomic data to identify a species of bacteria, or at least find its close relatives. But fast techniques to sequence genomes have flooded the public databases and in a biased fashion, containing lots of genomic data about some species and not enough about others, according to a Rice University computer scientist.

31 Oct 2018

Genome News and Research

New research explains how large virus shells are formed

Genetic factors linked to obesity may lower metabolic risk

Illumina signs agreement to acquire Pacific Biosciences

Zinc can protect against oxidative stress when taken along with coffee, tea, and chocolate

UCLA researchers investigate how a protein factor contributes to cancer cell migration

Scientists decode the longest ever continuous DNA sequence

Observing functional changes of cells in blood vessels may help detect early signs of atherosclerosis

Presence of rare mutations indicates increased risk from interval breast cancers

Repair defect in neurons hints at possible therapy for preventing ALS

UC Scientist receives NIH grant for developing new malaria therapeutic strategies

UA scientists aim to identify drug targets for rare pediatric cancer

FDA permits marketing of 23andme Personal Genome Service Pharmacogenetic Reports test

Genetic testing and breakthrough therapies may transform diagnosis, care of neuromuscular disease

CRISPR genome editing has foreseeable implications for plastic and reconstructive surgery

Growth of genomic databases hinders efforts to identify bacteria

Top researchers call for unified standards in 3D genome and epigenetic data

Using genome editing to prevent sudden cardiac death

Individual cells within the same heart cope differently with high blood pressure, study shows

Monkeys infected with Zika virus points to a sylvatic transmission cycle

NEC and Transgene sign MOU for strategic collaboration aimed at treating solid cancers

The art of CRISPR: The power and promise of gene editing eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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