Genes News and Research

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Transient chromosomal errors can spur the formation of tumors, study finds

A Ludwig Cancer Research study has found that inducing random chromosome instability (CIN) events in mice for as little as one week is enough to trigger harmful chromosomal patterns in cells that spur the formation of tumors.

16 Jul 2021

Combination of investigational therapeutic and chemotherapy shows promise for AML treatment

The investigational therapeutic ficlatuzumab in combination with chemotherapy showed signs of clinical efficacy in patients with relapsed/refractory acute myeloid leukemia.

16 Jul 2021

Single-cell RNA sequencing reveals cells that could protect from fatal lung disease

Single-cell RNA sequencing has revealed a subset of cells that could provide protection from a rare, but severely debilitating and fatal, lung disease.

16 Jul 2021

Human waste contamination in urban surface waters is driving the spread of 'superbugs'

Contamination of urban lakes, rivers and surface water by human waste is creating pools of 'superbugs' in Low- and Middle-Income Countries (LMIC) - but improving access to clean water, sanitation and sewerage infrastructure could help to protect people's health, a new study reveals.

15 Jul 2021

COVID-19 researchers review 184 drug repurposing candidates

New research describes the use of integrative bioinformatics analyses of transcriptomic profiles for COVID-19 therapeutics.

15 Jul 2021

Researchers find a promising avenue for more effective treatment of antibiotic-resistant bacteria

A small regulatory RNA found in many problematic bacteria, including Escherichia coli, appears to be responsible for managing the response of these bacteria to environmental stresses.

15 Jul 2021

Research sheds light on a new mechanism for inhibitory synapse specificity in the cortex

Researchers at the Max Planck Florida Institute for Neuroscience have discovered that the cell adhesion protein IgSF11 determines the layer-specific synaptic connectivity of a distinct class of cortical interneurons.

15 Jul 2021

A small molecule inhibitor shows promise to reduce the growth of uveal melanoma

Uveal melanoma, or UM, is a rare and deadly cancer of the eye, and the mortality rate has remained unimproved for 40 years. Half of the melanomas spread to other organs of the body, causing death in less than a year, so new treatments to preserve vision and prevent death are an urgent need.

15 Jul 2021

Aggressive type of cancer provides clues to how metastases form

A very aggressive type of cancer has provided a team of researchers supported by the Swiss National Science Foundation with an answer to the question of which tumor cells are at risk of spreading.

14 Jul 2021

SARS-CoV-2 variants show distinct humoral response and transcriptional profiles in hamster model

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a novel, highly infectious respiratory virus, and the causative agent of coronavirus disease 2019 (COVID-19) pandemic. SARS-CoV-2, which first originated in Wuhan, in Hubei province of China, is a member of the Coronavirdae family and has a large, non-segmented RNA genome.

14 Jul 2021

Bacteroides-dominant gut microbiome linked with advanced cognition and language skills in infant boys

The University of Alberta-led research followed more than 400 infants from the CHILD Cohort Study (CHILD) at its Edmonton site. Boys with a gut bacterial composition that was high in the bacteria Bacteroidetes at one year of age were found to have more advanced cognition and language skills one year later. The finding was specific to male children.

13 Jul 2021

Neutralizing aptamers block SARS-CoV-2 infection in vitro

A new study describes the clinical utility of aptamers against SARS-CoV-2.

13 Jul 2021

Understanding the molecular mechanisms behind lung cancer relapse

When a doctor gives a patient antibiotics for a bacterial infection, they usually require them to finish the entire treatment, even when symptoms go away.

13 Jul 2021

Researchers discover new set of signals that control production of goblet cells in the lung

Proper lung function relies on the precise balance of specialized epithelial cells (cells that line the surfaces of the body) that coordinate functions to maintain homeostasis.

13 Jul 2021

New study focuses on personalized therapies for people with severe asthma

A new phase 2 clinical trial of multiple therapies for severe asthma is underway in Northeast Ohio, with a focus on personalized therapies based on genetics, family history, lifestyle and environmental factors.

13 Jul 2021

USF receives $69.9 Million NIH funding to continue study on type 1 diabetes

The National Institutes of Health has awarded the University of South Florida total expected funds of $69.9 million over the next four years to continue the follow-up of study participants in The Environmental Determinants of Diabetes in The Young (TEDDY) consortium.

13 Jul 2021

Hematopoietic stem cells take advantage of 'junk' RNA to replenish the blood system

Chemotherapy is widely used to treat cancer patients. During the treatment, chemotherapeutic agents affect various biochemical processes to kill or reduce the growth of cancer cells, which divide uncontrollably in patients.

12 Jul 2021

Researchers gain new insights into the pathology of Usher syndrome

Human Usher syndrome (USH) is the most common form of hereditary deaf-blindness. Sufferers can be deaf from birth, suffer from balance disorders, and eventually lose their eyesight as the disease progresses.

12 Jul 2021

Researchers discover new genetic driver of autism and other developmental disorders

A research group including Kobe University's Professor TAKUMI Toru (also a Senior Visiting Scientist at RIKEN Center for Biosystems Dynamics Research) and Assistant Professor TAMADA Kota, both of the Physiology Division in the Graduate School of Medicine, has revealed a causal gene (Necdin, NDN) in autism model mice that have the chromosomal abnormality called copy number variation.

9 Jul 2021

Malfunction in the cell’s powerhouse causes sporadic Parkinson disease

The major cause of Parkinson’s Disease is a dysregulation of immune genes central for fighting against viruses, a new study reveals.

9 Jul 2021

Genes News and Research

Transient chromosomal errors can spur the formation of tumors, study finds

Combination of investigational therapeutic and chemotherapy shows promise for AML treatment

Single-cell RNA sequencing reveals cells that could protect from fatal lung disease

Human waste contamination in urban surface waters is driving the spread of 'superbugs'

COVID-19 researchers review 184 drug repurposing candidates

Researchers find a promising avenue for more effective treatment of antibiotic-resistant bacteria

Research sheds light on a new mechanism for inhibitory synapse specificity in the cortex

A small molecule inhibitor shows promise to reduce the growth of uveal melanoma

Aggressive type of cancer provides clues to how metastases form

SARS-CoV-2 variants show distinct humoral response and transcriptional profiles in hamster model

Bacteroides-dominant gut microbiome linked with advanced cognition and language skills in infant boys

Neutralizing aptamers block SARS-CoV-2 infection in vitro

Understanding the molecular mechanisms behind lung cancer relapse

Researchers discover new set of signals that control production of goblet cells in the lung

New study focuses on personalized therapies for people with severe asthma

USF receives $69.9 Million NIH funding to continue study on type 1 diabetes

Hematopoietic stem cells take advantage of 'junk' RNA to replenish the blood system

Researchers gain new insights into the pathology of Usher syndrome

Researchers discover new genetic driver of autism and other developmental disorders

Malfunction in the cell’s powerhouse causes sporadic Parkinson disease

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