Inflammation News and Research

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Anti-inflammatory diets could help lower the risk of breast cancer

Women eating more foods that increase inflammation in the body have a 12% increase in their risk of breast cancer relative to women who did not.

4 Jun 2021

Novel insights can open doors to combating clotting-related problems in COVID-19

Researchers scour what is known to come up with a hypothesis of why blood clots can be a major problem in COVID-19

4 Jun 2021

New biomaterial for pancreatic islet transplants does not trigger the body's immune response

A multidisciplinary research team led by Jonathan Lakey, Ph.D., professor of surgery and biomedical engineering at the University of California, Irvine, has developed a biomaterial for pancreatic islet transplants that doesn't trigger the body's immune response.

4 Jun 2021

Mast cell activation may underlie inflammation in severe COVID-19

A new preprint research paper posted to the medRxiv* server points to mast cells as major culprits in the etiology of severe and critical COVID-19. This could suggest suitable therapeutic and preventive interventions to reduce the morbidity and mortality of this viral illness.

3 Jun 2021

Secondary infections amplify the brain's immune response and affect memory in Alzheimer's disease

New research into Alzheimer's disease (AD) suggests that secondary infections and new inflammatory events amplify the brain's immune response and affect memory in mice and in humans - even when these secondary events occur outside the brain.

3 Jun 2021

Lung protein hyperconcentration may be a key factor in predicting COPD risks

Airway mucus consists of various proteins such as long mucins MUC5AC and MUC5B, both of which contribute greatly to the proper gel-like consistency of this most essential bodily fluid.

3 Jun 2021

Could a green tea compound combat SARS-CoV-2?

Researchers recently published an article that reviewed the mechanisms by which EGCG could inhibit SARS-CoV-2 infection and the various syndromes caused by COVID-19.

3 Jun 2021

New therapeutic approach developed to treat psoriatic arthritis

An international team of researchers, led by UC Davis Health, has developed a new therapeutic approach to treating psoriatic arthritis, a chronic inflammatory disease affecting the joints.

3 Jun 2021

Antibody treatment reactivates the immune defense in patients with advanced-stage cancer

Researchers at the University of Turku, Finland, showed that the antibody treatment reactivates the immune defense in patients with advanced-stage cancer.

3 Jun 2021

Patients with obesity at greater risk of developing long-term complications of COVID-19

A Cleveland Clinic study shows that survivors of COVID-19 who have moderate or severe obesity may have a greater risk of experiencing long-term consequences of the disease, compared with patients who do not have obesity.

3 Jun 2021

Hydroxychloroquine + Azithromycin therapy at a higher dose improved survival by nearly 200% in ventilated COVID patients

However, a fascinating new study posted to the medRxiv* preprint server suggests that such disappointment may have been both premature and unwarranted, based on a re-analysis of over 250 patients on invasive mechanical ventilation (IMV) during the first two months of the pandemic.

2 Jun 2021

People taking anti-inflammatory drug mount a weaker immune response to COVID-19 vaccine

One-quarter of people who take the drug methotrexate for common immune system disorders -- from rheumatoid arthritis to multiple sclerosis -- mount a weaker immune response to a COVID-19 vaccine, a new study shows.

2 Jun 2021

Long COVID patients at higher risk of small airway disease

The preprint discussed herein describes the effects of SARS-CoV-2 on lung structure and function in patients with long COVID.

2 Jun 2021

New insight into how platelets help resolve bacterial lung inflammation

Treating patients with acute respiratory failure is a constant challenge in intensive care medicine. In most cases, the underlying cause is lung inflammation triggered by a bacterial infection or - more rarely, despite being frequently observed at present due to the corona pandemic - a viral infection.

2 Jun 2021

Could higher carnitine levels in the blood protect against severe COVID-19?

Researchers at the MRC Integrative Epidemiology Unit (IEU), Bristol Medical School, University of Bristol, Bristol, UK, found that carnitine and its derivative acetyl-carnitine provide a protective effect against severe COVID-19. Doubling of carnitine or acetyl-carnitine is tied to a 40-percent reduction risk of disease progression.

2 Jun 2021

Could semen quality indicate SARS-CoV-2 insult susceptibility in polluted areas?

In a recent review in Environmental Science and Pollution Research, Italian researchers focused on “the evidence that correlates the degree and type of pollution with the increased susceptibility of many countries to this pandemic and proposes human semen as an early marker of the environmental health and the general health of individuals.” Their observations are based on a robust body of experimental evidence.

2 Jun 2021

Positive COVID-19 screening test helps monitor respiration rate, blood-oxygen saturation at home

Two easily measurable signs of health - respiration rate and blood-oxygen saturation - are distinctly predictive of higher mortality among patients hospitalized with COVID-19, according to a study examining the cases of inpatients with COVID-19 at Rush University Medical Center and University of Washington Medicine hospitals.

2 Jun 2021

Mice study shows that Western diet can lead to NASH, liver fibrosis

Apart from lifestyle interventions, there are currently no approved treatments for NASH. A liver transplant is sometimes the only remedy.

2 Jun 2021

Researchers find natural metabolites help SARS-CoV-2 escape antibodies

An international team of scientists has identified a human molecule — biliverdin — as a potential severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) target. The binding of the heme metabolite to the N-terminal domain of SARS-CoV-2 is associated with the virus’s ability to dodge the immune system by suppressing antibody binding to the spike protein.

2 Jun 2021

Direct action of SARS-CoV-2 on organs may lead to exacerbated inflammatory response in pediatric patients

Besides common symptoms such as fever, cough and respiratory distress, some children have an atypical form of COVID-19 known as multisystem inflammatory syndrome in children (MIS-C), characterized by persistent fever and inflammation of several organs, such as the heart and intestines, as well as the lungs to a lesser extent.

1 Jun 2021

Inflammation News and Research

Anti-inflammatory diets could help lower the risk of breast cancer

Novel insights can open doors to combating clotting-related problems in COVID-19

New biomaterial for pancreatic islet transplants does not trigger the body's immune response

Mast cell activation may underlie inflammation in severe COVID-19

Secondary infections amplify the brain's immune response and affect memory in Alzheimer's disease

Lung protein hyperconcentration may be a key factor in predicting COPD risks

Could a green tea compound combat SARS-CoV-2?

New therapeutic approach developed to treat psoriatic arthritis

Antibody treatment reactivates the immune defense in patients with advanced-stage cancer

Patients with obesity at greater risk of developing long-term complications of COVID-19

Hydroxychloroquine + Azithromycin therapy at a higher dose improved survival by nearly 200% in ventilated COVID patients

People taking anti-inflammatory drug mount a weaker immune response to COVID-19 vaccine

Long COVID patients at higher risk of small airway disease

New insight into how platelets help resolve bacterial lung inflammation

Could higher carnitine levels in the blood protect against severe COVID-19?

Could semen quality indicate SARS-CoV-2 insult susceptibility in polluted areas?

Positive COVID-19 screening test helps monitor respiration rate, blood-oxygen saturation at home

Mice study shows that Western diet can lead to NASH, liver fibrosis

Researchers find natural metabolites help SARS-CoV-2 escape antibodies

Direct action of SARS-CoV-2 on organs may lead to exacerbated inflammatory response in pediatric patients

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Bringing real-time analytics to downstream bioprocess monitoring

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Evaluating new approaches for rare disease genomics

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