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Scientists identify a distinct role of retinoic acid during immune response of the gut

A team of scientists from the Renaissance School of Medicine at Stony Brook University have identified a distinct role of retinoic acid, a metabolite of vitamin A, during the immune response of the gut.

28 Mar 2023

Notorious oncogene plays a direct role in disguising growing cancers from the immune system

Cancer-associated genes called oncogenes are well known to stimulate cell growth and division — causing tumors to balloon and spread.

28 Mar 2023

Truly random drug testing: ADHD patients face uneven urine screens and, sometimes, stigma

Some adults who take prescription medication for attention-deficit/hyperactivity disorder are required to have their urine tested for drugs several times a year. Others never are tested.

28 Mar 2023

Study details bacterial agents in 418 ticks extracted from humans in France

In a recent study published in the journal Emerging Infectious Diseases, researchers analyzed ticks that bit humans between January 2014 and March 2021 in France for the presence of bacterial pathogens.

27 Mar 2023

Case report on Nocardia pseudobrasiliensis and SARS-CoV-2 concomitant infection

In a recent case report published in the U.S. Centers for Disease Control and Prevention’s (CDC) journal Emerging Infectious Diseases, researchers reported a case of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and Nocardia pseudobrasiliensis concomitant infection.

27 Mar 2023

Pneumolysin toxin holds promise for developing therapies against Streptococcus pneumoniae

In a recent study published in the journal PLoS ONE, researchers in Spain performed a systematic review of pneumolysin (PLY) toxin as a molecular target to develop novel therapeutics against Streptococcus pneumoniae.

27 Mar 2023

Compassion could reduce self-criticism, body shaming and depression in obese people

University of Queensland researchers have found compassion could reduce self-criticism, body shaming and depression in overweight or obese adults.

27 Mar 2023

Researchers receive NCI grant to advance new treatment approach for pancreatic cancer

Cosimo Commisso, Ph.D., and Susanne Heynen-Genel, Ph.D., have received a grant from the National Cancer Institute to advance a new treatment approach for pancreatic cancer.

27 Mar 2023

Developers of gene therapies can utilize FDA guidance to prepare ODD or RPDD applications

Providing an overview of the submissions process and examples of U.S. Food and Drug Administration (FDA) applications for Orphan Drug Designation (ODD) and Rare Pediatric Disease Designation (RPDD), a new article can help developers of gene therapies for rare genetic diseases.

27 Mar 2023

Myeloid cells can harbor HIV in people taking antiretroviral therapy

A subset of white blood cells, known as myeloid cells, can harbor HIV in people who have been virally suppressed for years on antiretroviral therapy, according to findings from a small study supported by the National Institutes of Health.

27 Mar 2023

Targeting the STING pathway with a combination strategy promotes antitumor activity

Immunotherapies have greatly improved the outcomes of many patients with melanoma. But there is still a need for new approaches for the subset of patients who do not respond well to this type of therapy.

27 Mar 2023

Updated expert consensus statement on transcatheter left atrial appendage closure released

Today, the Society for Cardiovascular Angiography & Interventions and the Heart Rhythm Society released an updated expert consensus statement on transcatheter left atrial appendage closure (LAAC).

27 Mar 2023

Light therapy may benefit heart health and longevity

Light therapy has demonstrated its usefulness in treating a variety of diseases. But can it delay the occurrence of age-related disease?

27 Mar 2023

Shin splints impact more muscles than previously thought, study finds

Unfortunately, most runners will experience shin splints at some point, and though questions remain about what causes this lower leg pain and how to fix it, one thing’s clear: At their worst, shin splints can be debilitating and excruciating.

27 Mar 2023

Study adds valuable new information on the treatment of COVID-19

Although steroid treatment for COVID-19 is reportedly beneficial in some cases, details—such as the upper dosing limits and safety of this method—have not yet been clarified.

27 Mar 2023

Monocytes may be a stable reservoir of HIV in patients taking antiretroviral therapy

To develop treatments that may one day entirely rid the body of HIV infection, scientists have long sought to identify all of the places that the virus can hide its genetic code.

27 Mar 2023

Is nirmatrelvir treatment of SARS-CoV-2 associated with a lower risk of post–COVID-19 condition?

Researchers performed an observational cohort study using the US Department of Veterans Affairs healthcare databases.

27 Mar 2023

Metformin may reduce the risk of osteoarthritis

In a recent study published in JAMA Network Open, researchers in the United States (US) determined the risk of osteoarthritis (OA) and joint replacement among adults with type 2 diabetes (T2D) following metformin or sulfonylurea treatment.

27 Mar 2023

A randomized trial of a blood thinner after severe COVID-19 to prevent clotting events

In a recent prospective study published in the Annals of Internal Medicine Journal, researchers in the United States (US) and Spain performed a randomized controlled trial (RCT) across 127 US hospitals between 2021 and 2022.

27 Mar 2023

Intermittent fasting shows potential benefits for obesity treatment and brain-gut-microbiome health

A recent Nutrients journal study by researchers at the David Geffen School of Medicine at the University of California, Los Angeles, has discussed the effects of time-restricted eating on BGM and reviewed its promising effects in obesity treatment.

26 Mar 2023

Therapy News and Research

Scientists identify a distinct role of retinoic acid during immune response of the gut

Notorious oncogene plays a direct role in disguising growing cancers from the immune system

Truly random drug testing: ADHD patients face uneven urine screens and, sometimes, stigma

Study details bacterial agents in 418 ticks extracted from humans in France

Case report on Nocardia pseudobrasiliensis and SARS-CoV-2 concomitant infection

Pneumolysin toxin holds promise for developing therapies against Streptococcus pneumoniae

Compassion could reduce self-criticism, body shaming and depression in obese people

Researchers receive NCI grant to advance new treatment approach for pancreatic cancer

Developers of gene therapies can utilize FDA guidance to prepare ODD or RPDD applications

Myeloid cells can harbor HIV in people taking antiretroviral therapy

Targeting the STING pathway with a combination strategy promotes antitumor activity

Updated expert consensus statement on transcatheter left atrial appendage closure released

Light therapy may benefit heart health and longevity

Shin splints impact more muscles than previously thought, study finds

Study adds valuable new information on the treatment of COVID-19

Monocytes may be a stable reservoir of HIV in patients taking antiretroviral therapy

Is nirmatrelvir treatment of SARS-CoV-2 associated with a lower risk of post–COVID-19 condition?

Metformin may reduce the risk of osteoarthritis

A randomized trial of a blood thinner after severe COVID-19 to prevent clotting events

Intermittent fasting shows potential benefits for obesity treatment and brain-gut-microbiome health

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