Apoptosis News and Research

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Apoptosis is programmed cell death, the body's normal method of disposing of damaged, unwanted, or unneeded cells.

Researchers investigate how messenger substances signal inflammation during damaged cell removal

A research team from Cologne and Osnabrück has investigated in detail how messenger substances signal inflammation during the removal of damaged cells in the body.

4 Feb 2022

Researchers identify a cellular pathway that causes pancreatic beta cells to die in type 1 diabetes

A central feature of type 1 diabetes is loss of the pancreatic beta cells that make insulin. Researchers led by Paolo Fiorina, MD, PhD, of Boston Children's Hospital and Francesca D'Addio, MD, of the University of Milan now identify a harmful cellular pathway that causes these cells to die.

3 Feb 2022

Relationship between SARS-CoV-2 neurotropism and Alzheimer's disease

In a new study, researchers evaluated the neurotropism of SARS-CoV-2 and its impact on COVID-19 patients with and without neurological disorders like Alzheimer's disease.

3 Feb 2022

Representative structures of SARS-CoV-2 and development of therapeutic agents for targeting these proteins

Researchers from China summarized the representative structures of SARS-CoV-2 proteins and discussed the development of novel therapeutic agents for targeting these proteins to treat and prevent COVID-19.

2 Feb 2022

MCL1 regulates neuronal autophagy, cell survival in Alzheimer's disease

Announcing a new review article publication for Acta Materia Medica journal. In this review article, the authors discuss the emerging neuroprotective function of MCL1 and how dysregulation of MCL1 signaling is involved in the pathogenesis of AD.

31 Jan 2022

Imaging microscopy shows killer T-cells targeting SARS-CoV-2 spike protein

Researchers demonstrate how cytotoxic T-lymphocytes (CTLs) with specificity for SARS-CoV-2 eliminate multiple infected targets.

30 Jan 2022

Research opens up new avenues for cancer treatment

Researchers at Koç University discovered why a promising class of cancer treatments fail, and their findings point to how such treatments might be made to work.

28 Jan 2022

Studying the effect of COVID-19 mRNA vaccine on human lung carcinoma epithelial cells using Raman spectroscopy and imaging

Researchers from the Lodz University of Technology have been investigating the effects of the mRNA COVID-19 vaccines on human lung carcinoma cells.

28 Jan 2022

T-cell apoptosis linked to poor prognosis among COVID-19 patients

Researchers assess the probability of T-cell apoptosis in patients with severe COVID-19 who were admitted to the hospital.

26 Jan 2022

Study finds overexpression of 3 SARS-CoV-2 genes could globally compromise transcriptome of human pluripotent stem cell-derived cardiomyocytes

In a recent study, whole mRNA-seq was used to investigate the global effects of SARS-CoV-2 viral genes Nsp6, Nsp8, and M on the transcriptome of hPSC-CMs.

26 Jan 2022

Nutritional components hold promise for improving the health and well-being of adults

Emerging research indicates that nutritional components that target specific mechanisms associated with age-associated cellular decline (AACD) hold promise for improving the health and well-being of adults.

25 Jan 2022

Broccoli compound triggers controlled cell death and recycling of cellular components in fission yeast

Broccoli may contain advantages beyond nutrition. A molecule found in broccoli, cabbage and more digests down into DIM, a compound with brighter benefits than the name implies, such as inducing cell death in breast, prostate and colon cancer.

24 Jan 2022

An algorithm to predict host cleavage targets of SARS-CoV-2 3CLPro

In a recent study posted to the bioRxiv* preprint server, researchers developed a novel bioinformatic algorithm to predict host cleavage targets of the SARS-CoV-2 3C-like protease (3CLPro).

23 Jan 2022

Study uncovers clue to why pigs don't get sick when exposed to COVID-19

Iowa State University scientists may have uncovered an important clue that sheds light on why pigs don't get sick when exposed to the coronavirus

20 Jan 2022

Chinese scientists reveal key role of lysosome cell death regulator in lung tumor survival

Chinese scientists recently reported the key role of histone acetylation-regulated long noncoding RNA termed as lysosome cell death regulator (LCDR) in tumor survival, providing a potential diagnostic and therapeutic target for lung cancer.

18 Jan 2022

Discovery opens up the possibility of pursuing new therapies for FOP

Fibrodysplasia ossificans progressiva (FOP) is a rare disease characterized by extensive bone growth outside of the normal skeleton that pre-empts the body's normal responses to even minor injuries. It results in what some term a "second skeleton," which locks up joint movement and could make it hard to breathe.

16 Jan 2022

Cannabidiol may improve innate immune response against SARS-CoV-2

A recent study shows evidence that cannabidiol, an important active ingredient in the Cannabis sativa plant, can augment the antiviral innate immune response and prophylactically prime the innate antiviral response of cells – enabling in turn improved response against viruses such as the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).

16 Jan 2022

Study shows that key parts of human immunity are shared in bacteria

The human immune system, that marvel of complexity, subtlety, and sophistication, includes a billion-year-old family of proteins used by bacteria to defend themselves against viruses, scientists at Dana-Farber Cancer Institute and in Israel have discovered.

13 Jan 2022

Study finds SARS-CoV-2 infection caused significant changes in the levels of stress associated small RNAs

In this study, researchers described the effect of significant changes of small RNAs in the post-transcriptional regulatory network.

13 Jan 2022

Using lab-grown stomachs to shed light on the symptoms of COVID-19

Could lab-grown 'mini-stomachs' be used to look at COVID-19 symptoms in children? In this interview, we speak to Paolo De Coppi to find out more.

13 Jan 2022

Apoptosis News and Research

Researchers investigate how messenger substances signal inflammation during damaged cell removal

Researchers identify a cellular pathway that causes pancreatic beta cells to die in type 1 diabetes

Relationship between SARS-CoV-2 neurotropism and Alzheimer's disease

Representative structures of SARS-CoV-2 and development of therapeutic agents for targeting these proteins

MCL1 regulates neuronal autophagy, cell survival in Alzheimer's disease

Imaging microscopy shows killer T-cells targeting SARS-CoV-2 spike protein

Research opens up new avenues for cancer treatment

Studying the effect of COVID-19 mRNA vaccine on human lung carcinoma epithelial cells using Raman spectroscopy and imaging

T-cell apoptosis linked to poor prognosis among COVID-19 patients

Study finds overexpression of 3 SARS-CoV-2 genes could globally compromise transcriptome of human pluripotent stem cell-derived cardiomyocytes

Nutritional components hold promise for improving the health and well-being of adults

Broccoli compound triggers controlled cell death and recycling of cellular components in fission yeast

An algorithm to predict host cleavage targets of SARS-CoV-2 3CLPro

Study uncovers clue to why pigs don't get sick when exposed to COVID-19

Chinese scientists reveal key role of lysosome cell death regulator in lung tumor survival

Discovery opens up the possibility of pursuing new therapies for FOP

Cannabidiol may improve innate immune response against SARS-CoV-2

Study shows that key parts of human immunity are shared in bacteria

Study finds SARS-CoV-2 infection caused significant changes in the levels of stress associated small RNAs

Using lab-grown stomachs to shed light on the symptoms of COVID-19

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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