Biomarker News and Research

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A biomarker is a biological molecule found in blood, other body fluids, or tissues that is a sign of a normal or abnormal process, or of a condition or disease. A biomarker may be used to see how well the body responds to a treatment for a disease or condition. Also called molecular marker and signature molecule.

Living in disadvantaged neighborhoods linked to Alzheimer’s biomarkers

People living in more disadvantaged neighborhoods may be more likely to have biomarkers for inflammation and Alzheimer's disease, according to a study published June 25, 2025, in Neurology, the medical journal of the American Academy of Neurology.

26 Jun 2025

Gut microbe emerges as a promising tool in the fight against COVID-19

Researchers found that Akkermansia muciniphila boosts lung-specific antiviral immunity against SARS-CoV-2 in mice by modulating the gut–lung axis. This commensal gut bacterium shows promise as a potential biomarker and biotherapeutic candidate for COVID-19 and other respiratory infections.

25 Jun 2025

IL-6 and CRP offer limited boost for predicting infections after lung cancer surgery

Early postoperative levels of IL-6 and CRP are independently associated with infection risk after pulmonary cancer surgery. However, adding these biomarkers to standard clinical predictors provides only limited improvement in infection prediction.

25 Jun 2025

Newborns and Alzheimer's patients have elevated blood levels of phosphorylated tau

Newborn babies and patients with Alzheimer's disease share an unexpected biological trait: elevated levels of a well-known biomarker for Alzheimer's.

24 Jun 2025

CIK treatment enhances survival in early and advanced colorectal cancer

Colorectal cancer (CRC) is the second most common cause of death from cancer in the United States (US) and the most prevalent malignant tumor worldwide.

24 Jun 2025

Simpler virus testing approach could reduce unnecessary PCR tests in high-risk settings

The COVID-19 pandemic yielded important advances in testing for respiratory viruses, but it also exposed important unmet needs in screening to prevent the spread of infections in high-risk settings.

24 Jun 2025

Excess trace metal levels may trigger gestational diabetes

Excess micronutrients in early pregnancy may raise gestational diabetes risks. Study links essential metal levels to GDM onset, urging a rethink on supplements.

24 Jun 2025

New genomic test predicts chemotherapy resistance in cancer patients

Chemotherapy seeks to destroy tumor cells and has been a standard treatment for cancer for decades.

24 Jun 2025

Capsule sponge test offers less invasive option for monitoring Barrett's esophagus

Endoscopies could be replaced by far less invasive capsule sponge tests for half of all patients with Barrett's esophagus, a known precursor to esophageal cancer, according to a new study from researchers at the University of Cambridge, Addenbrooke's Hospital and Queen Mary University of London.

23 Jun 2025

Inflammation drives early prostate cancer through cellular reprogramming

Prostate cancer is one of the most common cancers and the second leading cause of cancer-related death in men worldwide. However, the mechanisms controlling the early stages of prostate cancer formation are poorly understood.

23 Jun 2025

Melanoma’s excessive mitochondrial dependence becomes a therapeutic vulnerability

Researchers have discovered that the most aggressive melanomas, the deadliest form of skin cancer, overactivate two key processes in mitochondria, the components of cells that provide energy.

23 Jun 2025

Cord blood proteins help detect early sepsis in preterm infants

Scientists from Stanley Manne Children's Research Institute at Ann & Robert H. Lurie Children's Hospital of Chicago and colleagues identified several proteins from the umbilical cord blood of preterm newborns that signal acute systemic inflammation as an immune response to infection, providing objective and noninvasive means to diagnose early onset sepsis.

20 Jun 2025

Immune changes predict heart risks in cancer patients on checkpoint inhibitors

New research has uncovered immune changes in cancer patients that could help identify which patients are most at risk of dangerous heart complications from cancer drugs, known as immune checkpoint inhibitors.

20 Jun 2025

Targeting IGF2BP1 offers a new approach to cancer therapy

The RNA-binding protein IGF2BP1 has emerged as a key regulator of cancer hallmarks, influencing tumor proliferation, metastasis, immune evasion, and resistance to cell death.

20 Jun 2025

Why Alzheimer’s DNA tests don’t treat all populations equally

A major global study tested whether European-derived polygenic risk scores (PGS) for Alzheimer’s disease can predict risk across diverse populations. While PGS performed well in many groups, it was less accurate in individuals of sub-Saharan African and Indian ancestry, highlighting the urgent need for more inclusive genetic data.

19 Jun 2025

Brain age gap may influence the relationship between cognitive impairment risk factors

The difference between the brain's predicted age and actual chronological age, called a brain age gap, may influence the relationship between cognitive impairment risk factors, like high blood pressure and diabetes, and a person's cognitive performance, also known as thinking and memory skills, according to a study published June 18, 2025, in Neurology, the medical journal of the American Academy of Neurology.

19 Jun 2025

New molecular atlas offers unprecedented insight into human kidney function

The kidney, a critical organ for waste filtration and fluid regulation, is the subject of a groundbreaking molecular mapping project that could reshape our understanding of renal health.

18 Jun 2025

Heart disease markers may predict future cancer risk

Cancer and heart disease, two leading causes of death worldwide, may be more connected than we previously thought, according to a new UCLA Health study revealing that certain cardiac blood markers can strongly predict future cancer risk-even in people with no history or symptoms of heart disease.

18 Jun 2025

Mursla Bio introduces AI Precision Medicine Platform built on organ-specific EV isolation from blood

Mursla Bio, a leader in Extracellular Vesicle (EV) science on a mission to advance precision diagnostics and significantly improve cancer outcomes for at-risk patients, today announced the commercial launch of its AI Precision Medicine Platform, alongside a pre-print reporting the first validated method for isolating hepatocyte EVs from plasma for organ-specific proteomic and miRNA profiling. Mursla Bio is engaging with potential partners to apply its Platform to additional disease areas, biomarker discovery and IV

17 Jun 2025

Machine learning boosts accuracy of point-of-care disease detection

What if people could detect cancer and other diseases with the same speed and ease of a pregnancy test or blood glucose meter? Researchers at the Carl R. Woese Institute for Genomic Biology are a step closer to realizing this goal by integrating machine learning-based analysis into point-of-care biosensing technologies.

17 Jun 2025