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Phytoene increases lifespan, reduces oxidative stress and amyloid toxicity

Research indicates phytoene from microalgae protects against oxidative stress and beta-amyloid toxicity, suggesting its potential in promoting healthy aging.

30 Sep 2024

Owlstone Medical launches Breath Biopsy VOC Atlas® to unlock disease biomarkers in human breath

The Breath Biopsy VOC Atlas offers a comprehensive catalog of volatile organic compounds, enhancing understanding of breath biomarkers in health and disease.

From Owlstone Medical Ltd 30 Sep 2024

Glutathione found to significantly reduce acetaldehyde levels and help relieve hangovers

Study demonstrates that glutathione (GSH) significantly reduces acetaldehyde levels, a key factor in hangovers, though subjective symptoms showed little difference between groups. Pharmacokinetic data indicate that GSH accelerates acetaldehyde clearance, providing potential relief from hangover symptoms.

29 Sep 2024

12-week coffee compound study shows promising results for weight and fat reduction in at-risk individuals

Cafestol may aid in reducing body weight and visceral fat, but its impact on insulin sensitivity and glucose tolerance remains limited, according to the study.

27 Sep 2024

New drug MED6-189 shows promise against drug-resistant malaria

In 2022, nearly 619,000 global deaths due to malaria were caused by Plasmodium falciparum, the most virulent, prevalent, and deadly human malaria parasite.

26 Sep 2024

Purine metabolism disruptions highlighted as crucial in Parkinson’s disease development

Parkinson's disease (PD), the second most common neurodegenerative disorder globally, has long baffled scientists with its progressive nature and debilitating effects on motor function.

26 Sep 2024

Carotenoid phytoene shows potential in slowing Alzheimer’s plaque formation and increasing lifespan

Researchers from the Colour and Food Quality group at the Faculty of Pharmacy (University of Seville), in collaboration with Dr. Marina Ezcurra's group at the University of Kent (UK), have shown that the carotenoid phytoene increases the lifespan of the nematode Caenorhabditis elegans and can slow the onset of paralysis associated with the formation of amyloid plaques in a model of Alzheimer's disease.

26 Sep 2024

Researchers identify drug with anti-aging effects

Aging is an inevitable phenomenon and is accompanied by several comorbidities. To this end, research into the effects of aging has become paramount, and scientists are looking for ways to slow down aging and its detrimental impact on the human body.

25 Sep 2024

Chemical genetics uncovers promising anti-COVID compounds

This new article publication from Acta Pharmaceutica Sinica B, discusses the identification of novel small-molecule inhibitors of SARS-CoV-2 by chemical genetics.

25 Sep 2024

Optimized nanoadjuvants enhance in situ tumor vaccine for ovarian cancer

This new article publication from Acta Pharmaceutica Sinica B, discusses how molecular glue triggers degradation of PHGDH by enhancing the interaction between DDB1 and PHGDH.

25 Sep 2024

Combining treatments to boost tumor response in lung cancer

Researchers at the Francis Crick Institute, in collaboration with Revolution Medicines, have tested a combination of treatments in mice with lung cancer and shown that these allow immunotherapies to target non-responsive tumors.

25 Sep 2024

Study uncovers decision-making impairments linked to Parkinson's drug

Parkinson's disease (PD), also known simply as Parkinson's, is a disorder of the nervous system that affects millions of people worldwide.

24 Sep 2024

ACBI3 molecule offers new hope for targeting KRAS mutations in cancer

KRAS is the most mutated gene in cancer with mutations occurring in 17%–25% of all cancers, affecting millions of patients worldwide.

23 Sep 2024

Novel drug molecule offers hope for early Parkinson's disease treatment

A novel drug molecule could potentially lead to new treatments to prevent Parkinson's disease in younger patients, according to new research.

20 Sep 2024

Scientists investigate the rise in early-onset cancers and propose new strategies to combat growing epidemic

Researchers explore the global rise in early-onset cancers, linking environmental exposures and lifestyle changes to the surge, and advocate for tailored prevention and treatment strategies.

18 Sep 2024

Activation of PPARβ/δ-AMPK pathway shown to slow liver fibrosis development

A study led by Manuel Vázquez Carrera, group leader at the Diabetes and Associated Metabolic Diseases Networking Biomedical Research Centre (CIBERDEM) at the University of Barcelona, reveals advances in the understanding and treatment of liver fibrosis, a serious complication in the context of metabolic fatty liver disease, also known as MASLD (metabolic dysfunction-associated steatotic liver disease).

17 Sep 2024

Ohio State's novel DHODH inhibitor enters first human trials

A new therapeutic agent discovered and developed at The Ohio State University will soon be used for cancer treatment at the patient's bedside as part of a clinical trial.

17 Sep 2024

Newcells Biotech launches high-content and high-throughput imaging suite to advance pre-clinical drug development programmes

Newcells Biotech (“Newcells”), a leading drug discovery partner specialising in the development of in vitro models and bespoke assay services to improve the prediction of in vivo human outcomes, today announced the launch of its imaging suite and advanced lung Fibroblast-to-Myofibroblast Transition (FMT) assay.

From Newcells Biotech 17 Sep 2024

New research highlights role of dietary antioxidants in reducing erectile dysfunction risk

Researchers assess the association between erectile dysfunction and the Compound Dietary Antioxidant Index.

16 Sep 2024

Breakthrough in understanding formaldehyde toxicity during development and aging

AMeD syndrome is a severe genetic condition found in children that present with accelerated aging, global developmental delay and bone marrow failure, among others, progressing to Myelodysplastic Syndrome and Acute Myeloid Leukaemia.

13 Sep 2024

Compound News and Research

Phytoene increases lifespan, reduces oxidative stress and amyloid toxicity

Owlstone Medical launches Breath Biopsy VOC Atlas® to unlock disease biomarkers in human breath

Glutathione found to significantly reduce acetaldehyde levels and help relieve hangovers

12-week coffee compound study shows promising results for weight and fat reduction in at-risk individuals

New drug MED6-189 shows promise against drug-resistant malaria

Purine metabolism disruptions highlighted as crucial in Parkinson’s disease development

Carotenoid phytoene shows potential in slowing Alzheimer’s plaque formation and increasing lifespan

Researchers identify drug with anti-aging effects

Chemical genetics uncovers promising anti-COVID compounds

Optimized nanoadjuvants enhance in situ tumor vaccine for ovarian cancer

Combining treatments to boost tumor response in lung cancer

Study uncovers decision-making impairments linked to Parkinson's drug

ACBI3 molecule offers new hope for targeting KRAS mutations in cancer

Novel drug molecule offers hope for early Parkinson's disease treatment

Scientists investigate the rise in early-onset cancers and propose new strategies to combat growing epidemic

Activation of PPARβ/δ-AMPK pathway shown to slow liver fibrosis development

Ohio State's novel DHODH inhibitor enters first human trials

Newcells Biotech launches high-content and high-throughput imaging suite to advance pre-clinical drug development programmes

New research highlights role of dietary antioxidants in reducing erectile dysfunction risk

Breakthrough in understanding formaldehyde toxicity during development and aging

Enhancing confidence in chemical ionization spectrometry data eBook

Improving healthcare sustainability through carbon data

A New Approach to Preventing Bladder Cancer Recurrence

Bringing real-time analytics to downstream bioprocess monitoring

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