Nephropathy News and Research

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Nephropathy is a broad medical term used to denote disease or damage of the kidney, which can eventually result in kidney failure. The primary and most obvious functions of the kidney are to excrete any waste products and to regulate the water and acid-base balance of the body – therefore loss of kidney function is a potentially fatal condition.

Research findings provide insights into risks associated with isolated mild hyperglycemia

Despite having mild hyperglycemia for approximately 50 years, patients with a mutation in the gene encoding the enzyme glucokinase had a low prevalence of clinically significant vascular complications, findings that provide insights into the risks associated with isolated mild hyperglycemia, according to a study in the January 15 issue of JAMA.

15 Jan 2014

MRI method to map creatine in heart may help detect disorders earlier than traditional methods

A new MRI method to map creatine at higher resolutions in the heart may help clinicians and scientists find abnormalities and disorders earlier than traditional diagnostic methods, researchers at the Perelman School of Medicine at the University of Pennsylvania suggest in a new study published online today in Nature Medicine.

13 Jan 2014

Gastric bypass and cardiovascular disease risk: an interview with Dr. Brethauer, Cleveland Clinic

Gastric bypass surgery is a type of bariatric operation that results in weight loss and stimulates metabolic effects that treat diabetes and other cardiovascular risk factors such as diabetes, high cholesterol, and hypertension.

9 Jan 2014

OxThera announces initiation of Oxabact clinical study in Primary Hyperoxaluria

OxThera AB, a Stockholm-based privately-held biopharmaceutical company, today announced that it has initiated a clinical study in Primary Hyperoxaluria. This announcement bolsters the Company's position as a leader in developing therapies for hyperoxaluria, a debilitating condition that, if untreated, leads to kidney damage and end-stage renal disease.

8 Jan 2014

StemGenex offers stem cell treatment studies to patients diagnosed with diabetes, neurological diseases

According to The American Diabetes Association there are over 25 million people in the US living with diabetes. These patients are suffering from complications such as heart disease, stroke, high blood pressure, blindness, kidney disease, neuropathy and amputation.

8 Jan 2014

Shield Therapeutics reports positive top-line data from pivotal Phase 3 programme of ST10

Shield Therapeutics, an independent specialty pharmaceutical company focused on the development of mineral-derived hospital pharmaceuticals, today announces strongly positive top-line data from the pivotal Phase 3 programme of ST10 for the treatment of iron deficiency anaemia in inflammatory bowel disease.

7 Jan 2014

EMA accepts Otsuka's marketing authorisation application for tolvaptan for treatment of ADPKD

Otsuka Pharmaceutical Co., Ltd. announced today that the European Medicines Agency (EMA) has accepted the submission of a marketing authorisation application (MAA) for the potential approval of tolvaptan for the treatment of autosomal dominant polycystic kidney disease (ADPKD).

27 Dec 2013

Holiday reads: Squabbling families, the psychology of Santa, holiday stress and chocolate chip cookies

[T]his time of year the Internet is ripe with lists on how to avoid or mitigate family conflicts. At big gatherings, familiarity may not always breed contempt, but it sure can breed festering emotional wounds. Leonard Felder, a Los Angeles psychologist, has found that about three-quarters of us have at least one family member who annoys us. But why is it that the same minor jabs and annoying tics that are harmless coming from friends prompt epic screaming matches when uttered by relatives? ... Here are four theories as to why our families drive us nuts, and it would be nice of you to pay attention for once in your life (Olga Khazan, 12/23).

24 Dec 2013

Paired exchange and incompatible kidney transplant program launched by UAB

Ann Marie Reynolds, a 32-year-old who has been in and out of hospitals fighting chronic kidney disease since she was a teenager, had a less than 1 percent chance of receiving a kidney without the University of Alabama at Birmingham's groundbreaking organ donation system that helped her and two other hard-to-match patients get kidneys in a three-way, incompatible kidney exchange earlier this year.

24 Dec 2013

Most frequent reasons for readmission often related to patients' underlying chronic medical conditions

Researchers cite identification and monitoring of known underlying chronic medical conditions as opportunities to reduce readmission rates and improve patient safety.

24 Dec 2013

ANP reports positive interim results from ATL1103 Phase II clinical trial for acromegaly

Antisense Therapeutics Limited is pleased to advise that positive results have been achieved from the interim analysis of a subset of available data from its Phase II clinical trial of ATL1103 in patients with the growth disorder, acromegaly.

23 Dec 2013

Baxter’s VIVIA hemodialysis system receives CE marking in Europe

Baxter International Inc. today announced completion of CE marking in Europe for the VIVIA hemodialysis system, designed to deliver more frequent, extended duration, short daily or nocturnal home HD therapy, known as High Dose HD therapy.

From Baxter International Inc. 20 Dec 2013

New guideline to help doctors treat patients with hypertension

A new guideline developed by evidence gathered from randomized clinical trials for the management of high blood pressure contains nine recommendations and a treatment algorithm to help doctors treat patients with hypertension.

19 Dec 2013

ASH and ISH release guidelines for diagnosis and treatment of hypertension

High blood pressure affects approximately one in three adults in the Americas, Europe, some Asian countries and Australia, and one billion people worldwide.

18 Dec 2013

UCLA researchers find no evidence of association between iron levels and atherosclerosis risk

A UCLA research team has found no evidence of an association between iron levels in the body and the risk of atherosclerosis, the hardening and narrowing of the arteries that leads to cardiovascular disease, the No. 1 killer in the U.S.

18 Dec 2013

ASH, ISH create new guidelines for diagnosis and treatment of hypertension

High blood pressure affects approximately one in three adults in the Americas, Europe, some Asian countries and Australia, and one billion people worldwide. Because of this epidemic, The American Society of Hypertension, Inc. and the International Society of Hypertension are pleased to announce the creation of first-of-their-kind guidelines for the diagnosis and treatment of Hypertension: "Clinical Practice Guidelines for the Management of Hypertension in the Community."

17 Dec 2013

FDA accepts Shield Therapeutics' IND application to begin ST10 Phase 3 pivotal study for IDA treatment

Shield Therapeutics, an independent specialty pharmaceutical company focused on the development of mineral-derived hospital pharmaceuticals, today announces that the US Food and Drug Administration has accepted its Investigational New Drug application to initiate a Phase 3 pivotal study of ST10, its novel oral iron-replacement therapy, for the treatment of iron deficiency anaemia in pre-dialysis patients with chronic kidney disease. The Company plans to initiate the Phase 3 study in the US in H1 2014 and positive data would be the cornerstone of a subsequent NDA submission.

16 Dec 2013

IOF Young Investigator Awards presented to five researchers at 4th Asia-Pacific Osteoporosis Meeting

Today, the International Osteoporosis Foundation recognized the outstanding work of five young researchers from China, Chinese Taipei, Hong Kong, Malaysia and Pakistan.

16 Dec 2013

New UCSF-led study links obesity to development of chronic kidney disease

A new UCSF-led study of nearly 3,000 individuals links obesity to the development of kidney disease. The work also shows that, when properly measured, declines in kidney function are detectable long before the emergence of other obesity-related diseases such as diabetes and high blood pressure.

14 Dec 2013

Exercise may slow kidney function decline in kidney disease patients

Increased physical activity may slow kidney function decline in patients with kidney disease, according to a study appearing in an upcoming issue of the Journal of the American Society of Nephrology. The findings suggest that exercise could have a powerful effect on maintaining patients' health.

13 Dec 2013

Nephropathy News and Research

Further Reading

Research findings provide insights into risks associated with isolated mild hyperglycemia

MRI method to map creatine in heart may help detect disorders earlier than traditional methods

Gastric bypass and cardiovascular disease risk: an interview with Dr. Brethauer, Cleveland Clinic

OxThera announces initiation of Oxabact clinical study in Primary Hyperoxaluria

StemGenex offers stem cell treatment studies to patients diagnosed with diabetes, neurological diseases

Shield Therapeutics reports positive top-line data from pivotal Phase 3 programme of ST10

EMA accepts Otsuka's marketing authorisation application for tolvaptan for treatment of ADPKD

Holiday reads: Squabbling families, the psychology of Santa, holiday stress and chocolate chip cookies

Paired exchange and incompatible kidney transplant program launched by UAB

Most frequent reasons for readmission often related to patients' underlying chronic medical conditions

ANP reports positive interim results from ATL1103 Phase II clinical trial for acromegaly

Baxter’s VIVIA hemodialysis system receives CE marking in Europe

New guideline to help doctors treat patients with hypertension

ASH and ISH release guidelines for diagnosis and treatment of hypertension

UCLA researchers find no evidence of association between iron levels and atherosclerosis risk

ASH, ISH create new guidelines for diagnosis and treatment of hypertension

FDA accepts Shield Therapeutics' IND application to begin ST10 Phase 3 pivotal study for IDA treatment

IOF Young Investigator Awards presented to five researchers at 4th Asia-Pacific Osteoporosis Meeting

New UCSF-led study links obesity to development of chronic kidney disease

Exercise may slow kidney function decline in kidney disease patients

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

The impact of vibration on microscopy

How Omics Technologies Are Transforming Biological Research and Drug Discovery

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