Neurodegenerative Disease News and Research

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GUMC receives FDA clearance to begin clinical study of cancer drug in patients with Alzheimer's disease

Georgetown University Medical Center today announces the U.S. Food and Drug Administration has completed its review of an investigational new drug application (IND) for the use of nilotinib in a phase II clinical trial for patients with mild to moderate Alzheimer's disease.

30 Sep 2016

Research shows degenerative diseases affecting the retina may be treatable with gene therapy

Researchers have demonstrated the ability to deliver a fully functional copy of the CLN3 gene to stem cells of patients with juvenile NCL, an inherited neurodegenerative disease in which a mutation in the CLN3 gene causes early-onset severe central vision loss.

26 Sep 2016

Research re-opens door to possibility of stopping ongoing brain damage

A breakthrough in understanding how brain damage spreads - and how it could potentially be limited - has been made through a collaboration between neuroscientists and engineers at the Universities of Dundee and Strathclyde.

21 Sep 2016

MR Solutions receives order for cryogen-free 7T simultaneous PET-MR preclinical imaging system

MR Solutions has received an order for a high-powered 7T, cryogen-free, preclinical PET-MRI multi-modality imaging system from the newly formed pre-clinical imaging resource at the Zilkha Neurogenetic Institute (ZNI) at the Keck School of Medicine of the University of Southern California (USC).

21 Sep 2016

Researchers propose new way for early diagnosis of neurodegenerative diseases

A preclinical test that may open new perspectives in the diagnosis of neurological disorders. This is the result accomplished by a group of researchers from the Center of Complexity and Biosystems of the University of Milan, who just published their work on 'Physical Review Applied'.

21 Sep 2016

Memory loss symptoms not sufficient to diagnose other forms of Alzheimer's

Relying on clinical symptoms of memory loss to diagnose Alzheimer's disease may miss other forms of dementia caused by Alzheimer's that don't initially affect memory, reports a new Northwestern Medicine study.

13 Sep 2016

Scientists developing virtual reality-based early diagnosis system for neurodegenerative disorders

Scientists from Tomsk Polytechnic University and Siberian State Medical University are developing an early diagnosis system for neurodegenerative disorders.

2 Sep 2016

Multi-purpose protein may offer clues for successful treatment of Alzheimer's disease

The tidal wave approaches. In the coming decades, Alzheimer's disease is projected to exact a devastating economic and emotional toll on society, with patient numbers in the US alone expected to reach 13.5 million by mid-century at a projected cost of over a trillion dollars.

30 Aug 2016

Basic cell biology research into neurodegeneration may fuel understanding of neurodegenerative diseases

Clinical trials and translational medicine have certainly given people hope and rapid pathways to cures for some of mankind's most troublesome diseases, but now is not the time to overlook the power of basic research, says UC Santa Barbara neuroscientist Kenneth S. Kosik.

27 Aug 2016

Novel marine natural product appears to reduce pancreatic tumor size

Scientists at Florida Atlantic University's Harbor Branch Oceanographic Institute found that a deep-water marine sponge collected off of Fort Lauderdale's coast contains leiodermatolide, a natural product that has the ability to inhibit the growth of cancer cells as well as block cancer cells from dividing using extremely low concentrations of the compound.

18 Aug 2016

Inosine treatment can help restore motor control after cortical injury

Brain tissue can die as the result of stroke, traumatic brain injury, or neurodegenerative disease. When the affected area includes the motor cortex, impairment of the fine motor control of the hand can result.

3 Aug 2016

Large study of familial ALS finds new gene variant present in 3% of all patients with disease

Variations in a gene with multiple functions in neurons are present in approximately 3 percent of all cases of ALS in North American and European populations, both sporadic and familial, making it one of the most common genetic causes of the disease, according to a paper published in Nature Genetics.

26 Jul 2016

Promising new therapeutic target could lead to better prognosis of spinal muscular atrophy

According to studies, approximately one out of every 40 individuals in the United States is a carrier of the gene responsible for spinal muscular atrophy (SMA), a neurodegenerative disease that causes muscles to weaken over time.

25 Jul 2016

DPUK brings organisations together to tackle dementia across the UK

Dementia, is an overall term that describes a wide range of symptoms that includes memory loss and difficulties with thinking, is caused when the brain cells degenerate and die more quickly than they would as part of the normal ageing process.

21 Jul 2016

Researchers develop new screening system to measure protein aggregates

Researchers from the Massachusetts Institute of Technology and Boston University have developed a system capable of quickly screening millions of yeast cells to measure protein aggregates.

15 Jul 2016

VIB research reveals new insights into ALS

Research into amyotrophic lateral sclerosis (ALS) conducted by VIB-KU Leuven has led to interesting and unexpected conclusions.

14 Jul 2016

Scientists identify timing of major metabolic shift in developing neurons

Our brains can survive only for a few minutes without oxygen. Salk Institute researchers have now identified the timing of a dramatic metabolic shift in developing neurons, which makes them become dependent on oxygen as a source of energy.

13 Jul 2016

Neuroscientists identify two distinct populations of dopamine neurons involved in movement, reward

Two Northwestern University neuroscientists have identified the neurochemical signal likely missing in Parkinson's disease by being the first to discover two distinctly different kinds of neurons that deliver dopamine to an important brain region responsible for both movement and learning/reward behavior.

12 Jul 2016

TBI with LOC linked to late-life neurodegeneration but not Alzheimer's disease

Traumatic brain injury (TBI) with a loss of consciousness (LOC) may be associated with later development of Parkinson's disease but not Alzheimer's disease or incident dementia, according to a study conducted at the Icahn School of Medicine at Mount Sinai and the University of Washington School of Medicine.

11 Jul 2016

Study shows miR-19 helps new neurons in the adult brain stay on track

A small stretch of ribonucleic acid called microRNA could make the difference between a healthy adult brain and one that's prone to disorders including schizophrenia.

8 Jul 2016

Neurodegenerative Disease News and Research

GUMC receives FDA clearance to begin clinical study of cancer drug in patients with Alzheimer's disease

Research shows degenerative diseases affecting the retina may be treatable with gene therapy

Research re-opens door to possibility of stopping ongoing brain damage

MR Solutions receives order for cryogen-free 7T simultaneous PET-MR preclinical imaging system

Researchers propose new way for early diagnosis of neurodegenerative diseases

Memory loss symptoms not sufficient to diagnose other forms of Alzheimer's

Scientists developing virtual reality-based early diagnosis system for neurodegenerative disorders

Multi-purpose protein may offer clues for successful treatment of Alzheimer's disease

Basic cell biology research into neurodegeneration may fuel understanding of neurodegenerative diseases

Novel marine natural product appears to reduce pancreatic tumor size

Inosine treatment can help restore motor control after cortical injury

Large study of familial ALS finds new gene variant present in 3% of all patients with disease

Promising new therapeutic target could lead to better prognosis of spinal muscular atrophy

DPUK brings organisations together to tackle dementia across the UK

Researchers develop new screening system to measure protein aggregates

VIB research reveals new insights into ALS

Scientists identify timing of major metabolic shift in developing neurons

Neuroscientists identify two distinct populations of dopamine neurons involved in movement, reward

TBI with LOC linked to late-life neurodegeneration but not Alzheimer's disease

Study shows miR-19 helps new neurons in the adult brain stay on track

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