Genetic News and Research

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Hypertensive disorders of pregnancy associated with future cardiovascular risk

The current study, published in JAMA Network Open Cardiology, used Mendelian randomization (MR) to conduct a genome-wide association study (GWAS) on the relationship between these diseases to the risk of multiple CVD in the future.

21 Feb 2023

Skin medication shows promise in treating alcohol use disorder

Researchers from Oregon Health & Science University and institutions across the country have identified a pill used to treat a common skin disease as an "incredibly promising" treatment for alcohol use disorder.

21 Feb 2023

Mapping specialized receptors on mosquito nerve cells reveals why the insects are more attracted to some humans

In a bid to understand why mosquitoes may be more attracted to one human than another, Johns Hopkins Medicine researchers say they have mapped specialized receptors on the insects' nerve cells that are able to fine-tune their ability to detect particularly "welcoming" odors in human skin.

21 Feb 2023

Two new zebrafish models for studying the most common cause of Leigh syndrome developed

Researchers from Children's Hospital of Philadelphia (CHOP) developed two new zebrafish models for studying a specific genetic form of mitochondrial disease that represents the most common cause of Leigh syndrome.

21 Feb 2023

Study reports that depleting gut bacteria in mice with genetic risk for AD reduces neuropathology in a sex-dependent manner

Researchers highlight recent research investigating whether gut microbiota regulates tau pathology and tau-mediated neurodegeneration in an ApoE isoform–dependent manner.

21 Feb 2023

Oxford-Harrington Rare Disease Centre hosts virtual event in honor of the upcoming Rare Disease Day

The Oxford-Harrington Rare Disease Centre, a partnership of the University of Oxford and Harrington Discovery Institute at University Hospitals, is hosting a virtual event on Monday, Feb. 27, 2023, in honor of the upcoming Rare Disease Day, which is celebrated across the globe on February 28 every year.

21 Feb 2023

Researchers report the circulation of a novel MERS-like coronavirus in Malayan pangolins

Researchers reported the circulation of a novel MERS-like coronavirus among Malayan pangolins, Manis javanica HKU4-associated CoV (MjHKU4r-CoV).

21 Feb 2023

Researchers provide a framework for unifying and categorizing neurodegenerative diseases based on eight hallmarks

Researchers presented eight hallmarks of neurodegenerative diseases (NDDs), their in vivo biomarkers, and interactions to help categorize NDDs and specify patients within a specific NDD.

21 Feb 2023

Simple blood tests for telomeric protein could provide a valuable screen for certain cancers

Once thought incapable of encoding proteins due to their simple monotonous repetitions of DNA, tiny telomeres at the tips of our chromosomes seem to hold a potent biological function that's potentially relevant to our understanding of cancer and aging.

21 Feb 2023

HKU research advances understanding of the fundamental biological processes of gene regulation

A research team from the University of Hong Kong led by Professor Xiang David Li from the Department of Chemistry in collaboration with Dr Yuanliang Zhai from the HKU School of Biological Sciences and Dr Jason Wing Hon Wong and Dr Xiucong Bao from the HKU School of Biomedical Sciences recently made a key breakthrough in understanding how genetic information encoded in our DNA is 'read' and why errors in 'reading' such information can often lead to developmental defects or cancers.

20 Feb 2023

Structure of DREADD designer receptor could pave the way for creating next generation tools

In order to more fully understand how diseases arise in the brain, scientists must unravel the intricate way neurons relay messages (either chemical or electrical) along a complex web of nerve cells.

20 Feb 2023

Research reveals regional differences in the spread of Japan's two main ancestral groups

Regional differences in the spread of Japan's two main ancestral groups have been revealed, thanks to new research at the University of Tokyo.

20 Feb 2023

395 genes found to be differently expressed in people with type 2 diabetes

Researchers have identified 395 genes that are differently expressed in people with type 2 diabetes. One of the genes proved to be very strongly associated with impaired insulin secretion.

20 Feb 2023

In-depth assessment of muscle biopsies in patients with long COVID

Researchers analyzed skeletal muscle biopsies of patients with persistent fatigue and malaise post-exertion to determine the underlying mechanisms of long COVID.

20 Feb 2023

Genome editing prevents hypertrophic cardiomyopathy in mice

In a recent study published in the journal PLoS Digital Health, researchers pursued one-time cures for hypertrophic cardiomyopathy (HCM). They used a previously constructed murine model of HCM, designated as R403Q-129SvEv, to evaluate two different genetic therapies, as follows:

19 Feb 2023

Genetic News and Research

Hypertensive disorders of pregnancy associated with future cardiovascular risk

Skin medication shows promise in treating alcohol use disorder

Mapping specialized receptors on mosquito nerve cells reveals why the insects are more attracted to some humans

Two new zebrafish models for studying the most common cause of Leigh syndrome developed

Study reports that depleting gut bacteria in mice with genetic risk for AD reduces neuropathology in a sex-dependent manner

Oxford-Harrington Rare Disease Centre hosts virtual event in honor of the upcoming Rare Disease Day

Researchers report the circulation of a novel MERS-like coronavirus in Malayan pangolins

Researchers provide a framework for unifying and categorizing neurodegenerative diseases based on eight hallmarks

Simple blood tests for telomeric protein could provide a valuable screen for certain cancers

HKU research advances understanding of the fundamental biological processes of gene regulation

Structure of DREADD designer receptor could pave the way for creating next generation tools

Research reveals regional differences in the spread of Japan's two main ancestral groups

395 genes found to be differently expressed in people with type 2 diabetes

In-depth assessment of muscle biopsies in patients with long COVID

Genome editing prevents hypertrophic cardiomyopathy in mice

Mirror neurons for fighting found in mouse hypothalamus

Pluripotent stem cells can be a limitless source of transplantable HSPCs

Toxic protein may be the cause of muscular dystrophy and arhinia

Study reveals new clues to the underlying cause of FXS symptoms

Researchers use the drug fasudil to reverse two key symptoms of schizophrenia

Event guide: 2nd World RNA-Based Therapeutics & Vaccines Summit Korea eBook

Lab Matters host Harriet Gould on building a more connected lab community

The Critical Role of Sample Storage in Drug Discovery and Development

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

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