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Researchers engineer new weapon to destroy antibiotic-resistant bacteria

Over the past few decades, many bacteria have become resistant to existing antibiotics, and few new drugs have emerged.

2 Nov 2016

Scientists discover novel therapeutic target and treatment strategy for acute myeloid leukemia

University of Hawai'i Cancer Center researchers discovered a novel therapeutic target and treatment strategy for acute myeloid leukemia, a cancer of the blood and bone marrow that normally requires prompt and aggressive treatment.

2 Nov 2016

TSRI researchers uncover mechanism behind T cell exhaustion

In a new study with broad implications for treating cancers and chronic viral infections, scientists at The Scripps Research Institute (TSRI) have uncovered a mechanism behind a phenomenon called “T cell exhaustion.”

2 Nov 2016

Using deep learning to update the drug discovery paradigm: an interview with Professor Jackie Hunter

With the current drug discovery paradigm, it takes up to 15 years to translate an idea, such as hypothesizing a certain protein is important in a disease and testing this with targeting the protein with a drug, all the way through to proof of concept...

2 Nov 2016

Fred Hutchinson opens first-of-its-kind clinic to provide new immunotherapies for cancer patients

Fred Hutchinson Cancer Research Center today announced the official opening of a first-of-its-kind clinic dedicated to providing innovative immunotherapies for cancer patients in clinical trials.

2 Nov 2016

New imaging compound could help identify signs of early-stage Alzheimer's disease

By the time unambiguous signs of memory loss and cognitive decline appear in people with Alzheimer's disease, their brains already are significantly damaged, dotted with clumps of a destructive protein known as amyloid beta.

2 Nov 2016

TSRI scientists develop useful technique to unmask new functional features of human proteins

Scientists at The Scripps Research Institute have developed a broadly useful method to unmask new functional features of human proteins.

1 Nov 2016

Scientists discover how MEK inhibitor boosts antitumor activity and slows cancer progression

Understanding the effects of certain targeted therapies on antitumor immunity is necessary to design combined interventions for more effective cancer treatment.

1 Nov 2016

Study unravels how tobacco causes increased inflammation

It's no secret that using tobacco is bad for you, but what has been a mystery until now is how tobacco causes increased inflammation throughout the body.

31 Oct 2016

New biologic medication shows promise in treating multi-drug resistant HIV patients

A new biologic medication - the first for HIV - is showing promise in treating patients with multidrug resistance, according to phase 3 research being presented at IDWeek 2016.

31 Oct 2016

Blocking critical molecule with therapeutic antibody could effectively reduce leukemia burden

Acute myeloid leukemia (AML) is an aggressive cancer known for drug resistance and relapse. In an effort to uncover new treatment strategies, researchers at University of California San Diego School of Medicine and Moores Cancer Center discovered that a cell surface molecule known as CD98 promotes AML.

27 Oct 2016

NIH researchers identify novel role for Hsp60 protein in tissue regeneration and wound healing

National Institutes of Health researchers have identified a novel role for a gene known as heat shock protein 60 (Hsp60), finding that it is critical in tissue regeneration and wound healing.

27 Oct 2016

Supercomputer simulations of p53 protein could boost future anti-cancer drug discovery

Even though it's almost impossible to see, computational biophysicist Rommie Amaro is using the Stampede supercomputer at the Texas Advanced Computing Center at The University of Texas at Austin to model the largest atomic level system of the tumor suppression protein p53 to date -- over 1.5 million atoms.

27 Oct 2016

Vanderbilt scientists develop new bioluminescent sensor that can light up brain cells in the dark

A new kind of bioluminescent sensor causes individual brain cells to imitate fireflies and glow in the dark.

27 Oct 2016

Molecular biologist explores simple, innovative methods of developing new antibiotics

Antibiotic-resistant bacteria are a major problem worldwide. Molecular biologist Changsheng Wu explored innovative methods of developing new antibiotics more simply and more easily. He also discovered a new type of antibiotic.

27 Oct 2016

Researchers receive grant to investigate how gut microbiome influences breast cancer

Researchers from the University of Illinois at Chicago and the University of Chicago have received a three-year, $900,000 Defense Department grant to investigate how the gut microbiome – the trillions of bacteria, viruses and other bugs that make our digestive systems their home – influences breast cancer.

26 Oct 2016

Kent State scientists receive new NIH grants for reproductive biology research

It could be argued that no science is more valuable to us than that which helps to ensure the survival of our species by solving the problems that challenge it.

25 Oct 2016

Researchers design small compounds with potential to correct mitochondrial dysfunction

Charcot-Marie-Tooth disease is an inherited disorder that leads to a gradual loss of motor neurons and, eventually, paralysis. The condition is caused by genetic mutations that disrupts cells' energy factories, called mitochondria.

25 Oct 2016

New approach could overcome large immunosuppressive tumors

Harnessing the body's own immune system to destroy tumors is a tantalizing prospect that has yet to realize its full potential. However, a new advance from MIT may bring this strategy, known as cancer immunotherapy, closer to becoming reality.

24 Oct 2016

International scientists create first 3D atomic-level image of human cannabinoid receptor 1

In a discovery that advances the understanding of how marijuana works in the human body, an international group of scientists, including those from the Florida campus of The Scripps Research Institute (TSRI), have for the first time created a three-dimensional atomic-level image of the molecular structure activated by tetrahydrocannabinol (THC), the active chemical in marijuana.

24 Oct 2016

Molecule News and Research

Researchers engineer new weapon to destroy antibiotic-resistant bacteria

Scientists discover novel therapeutic target and treatment strategy for acute myeloid leukemia

TSRI researchers uncover mechanism behind T cell exhaustion

Using deep learning to update the drug discovery paradigm: an interview with Professor Jackie Hunter

Fred Hutchinson opens first-of-its-kind clinic to provide new immunotherapies for cancer patients

New imaging compound could help identify signs of early-stage Alzheimer's disease

TSRI scientists develop useful technique to unmask new functional features of human proteins

Scientists discover how MEK inhibitor boosts antitumor activity and slows cancer progression

Study unravels how tobacco causes increased inflammation

New biologic medication shows promise in treating multi-drug resistant HIV patients

Blocking critical molecule with therapeutic antibody could effectively reduce leukemia burden

NIH researchers identify novel role for Hsp60 protein in tissue regeneration and wound healing

Supercomputer simulations of p53 protein could boost future anti-cancer drug discovery

Vanderbilt scientists develop new bioluminescent sensor that can light up brain cells in the dark

Molecular biologist explores simple, innovative methods of developing new antibiotics

Researchers receive grant to investigate how gut microbiome influences breast cancer

Kent State scientists receive new NIH grants for reproductive biology research

Researchers design small compounds with potential to correct mitochondrial dysfunction

New approach could overcome large immunosuppressive tumors

International scientists create first 3D atomic-level image of human cannabinoid receptor 1

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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