immunity News and Research

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Intratumoral vaccination prolongs survival in mouse model of early stage resected pancreatic cancer

Building on their previous research focusing on vaccination within a tumor (intratumoral) for the most common form of pancreatic cancer, investigators from Rutgers Cancer Institute of New Jersey and Rutgers Robert Wood Johnson Medical School have shown that in a mouse model of early stage resected pancreatic cancer, intratumoral vaccination induces an anti-tumor response that results in a significant improvement in overall survival.

23 Mar 2017

Penn researcher receives $16.3 million NIAID grant to develop long-sought-after HIV vaccine

Building on earlier work in designing chimeric human-simian immunodeficiency viruses (SHIVs) that serve as a model of HIV infection of humans, George M. Shaw, MD, PhD, a professor of Hematology/Oncology and Microbiology in the Perelman School of Medicine at the University of Pennsylvania, has received $16.3 million over five years from the National Institute of Allergy and Infectious Diseases to develop a long-sought-after HIV vaccine.

22 Mar 2017

Review of research on wild primates underscores importance of super-spreaders in disease transmission

An extensive review of research on wild primate social networks and parasites underscores the importance of super-spreaders, or central individuals that play an outsized role in transmission of a pathogen.

21 Mar 2017

Immune cells could be new target to treat type 2 diabetes, hypertension in overweight people

Immune cells which are reduced in number by obesity could be a new target to treat diseases such as type 2 diabetes and hypertension that affect overweight people, according to a collaborative study between The University of Manchester, Lund University and the University of Salford.

From The University of Manchester 17 Mar 2017

Canadian scientists join international battle against Zika virus

The spread of the Zika virus, which can cause devastating birth defects, has become a pressing public health issue in many countries. To this day, there is no vaccine to prevent and no medicine to treat Zika virus infections.

16 Mar 2017

Study: Investigational Ebola vaccine regimen induced immune response that persisted for one year

A two-vaccine regimen intended to protect against Ebola virus disease induced an immune response that persisted for approximately one year in healthy adult volunteers, according to results from a Phase 1 clinical trial published in the March 14th issue of the Journal of the American Medical Association.

15 Mar 2017

New study examines immune responses to Ebola vaccines at one year after immunization

Immune responses to Ebola vaccines at one year after vaccination are examined in a new study appearing in the March 14 issue of JAMA.

14 Mar 2017

Pre-existing immunity to dengue virus modulates T cell response to Zika infection

Although Zika and dengue are considered different virus "species," they are so closely related that the immune system treats Zika just like another version of dengue, report researchers at La Jolla Institute for Allergy and Immunology.

13 Mar 2017

UCL scientists develop way to use MRI scans for identifying HIV in the brain

Scientists at UCL have developed a way to use MRI scans to help identify when HIV is persisting in the brain despite effective drug treatment.

13 Mar 2017

New study shows how activation of innate immunity promotes tissue regeneration

Houston Methodist researchers have identified an immune pathway that promotes the formation of a cell that can develop into new tissues and organs.

9 Mar 2017

Drug could activate innate anti-tumor immunity to eradicate aggressive prostate cancer in mice

Cabozantinib, a drug already used to treat patients with certain types of thyroid or kidney cancer, was able to eradicate invasive prostate cancers in mice by causing tumor cells to secrete factors that entice neutrophils - the first-responders of the immune system - to infiltrate the tumor, where they triggered an immune response that led to tumor clearance.

9 Mar 2017

Research findings show effective way to harness anti-tumor potential of macrophages in cancer therapy

For all the success of a new generation of immunotherapies for cancer, they often leave an entire branch of the immune system's disease-fighting forces untapped.

9 Mar 2017

UCLA researchers find ways to soften or stiffen up T cells for controlling immune response

T cells, the managers of our immune systems, spend their days shaking hands with another type of cell that presents small pieces of protein from pathogens or cancerous cells to the T cell.

8 Mar 2017

Study unravels protective mechanism that allows fruit flies to lay fewer eggs during bacterial infection

A protective mechanism that allows fruit flies to lay fewer eggs in response to bacterial infection is explained in a study published in the journal eLife.

7 Mar 2017

Study: More than ten million lives saved by discovery of cell strain in 1962

Nearly 200 million cases of polio, measles, mumps, rubella, varicella, adenovirus, rabies and hepatitis A -- and approximately 450,000 deaths from these diseases -- were prevented in the U.S. alone between 1963 and 2015 by vaccination, researchers estimate.

3 Mar 2017

Researchers develop smart genetic reference library for locating disease-causing mutations

Researchers at Hiroshima University have developed a smart genetic reference library for locating and weeding out disease-causing mutations in populations.

3 Mar 2017

Scientists propose rejuvenating bone marrow stem cell niche to boost immunity, fend off cancers

As people get older so do the hematopoietic stem cells (HSCs) that form their blood, creating an increased risk for compromised immunity and certain blood cancers. Now researchers are reporting in the scientific journal that the bone marrow niche where HSC's form also ages, contributing to the problem.

3 Mar 2017

Scientists track 'guardian immune cells' to uncover mechanics underlying inflammation and obesity

Scientists have uncovered the physiological mechanics underlying inflammation and obesity by tracking the actions of 'guardian immune cells' in response to changes in diet.

2 Mar 2017

Study increases understanding of how air pollution affects human health

Researchers from the University of Leicester have for the first time discovered that bacteria that cause respiratory infections are directly affected by air pollution - increasing the potential for infection and changing the effectiveness of antibiotic treatment.

2 Mar 2017

Immune system defect makes Addison’s patients prone to respiratory infections

Research led by University of Birmingham scientists has found that people suffering from the adrenal disorder known as Addison's disease suffer from an immune system defect which makes them prone to potentially deadly respiratory infections.

1 Mar 2017

immunity News and Research

Intratumoral vaccination prolongs survival in mouse model of early stage resected pancreatic cancer

Penn researcher receives $16.3 million NIAID grant to develop long-sought-after HIV vaccine

Review of research on wild primates underscores importance of super-spreaders in disease transmission

Immune cells could be new target to treat type 2 diabetes, hypertension in overweight people

Canadian scientists join international battle against Zika virus

Study: Investigational Ebola vaccine regimen induced immune response that persisted for one year

New study examines immune responses to Ebola vaccines at one year after immunization

Pre-existing immunity to dengue virus modulates T cell response to Zika infection

UCL scientists develop way to use MRI scans for identifying HIV in the brain

New study shows how activation of innate immunity promotes tissue regeneration

Drug could activate innate anti-tumor immunity to eradicate aggressive prostate cancer in mice

Research findings show effective way to harness anti-tumor potential of macrophages in cancer therapy

UCLA researchers find ways to soften or stiffen up T cells for controlling immune response

Study unravels protective mechanism that allows fruit flies to lay fewer eggs during bacterial infection

Study: More than ten million lives saved by discovery of cell strain in 1962

Researchers develop smart genetic reference library for locating disease-causing mutations

Scientists propose rejuvenating bone marrow stem cell niche to boost immunity, fend off cancers

Scientists track 'guardian immune cells' to uncover mechanics underlying inflammation and obesity

Study increases understanding of how air pollution affects human health

Immune system defect makes Addison’s patients prone to respiratory infections

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