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ChromDesign project trains budding scientists in 3D architecture of genome

How does the three-dimensional architecture of our genes affect the differentiation of cells and development of diseases? This is the question behind the European Innovation Training Network "ChromDesign- Chromatin and Design".

8 Nov 2018

Monash researchers provide insight into intricate peptide changes affecting immune system

Human leukocyte antigen molecules are a group of proteins that help the immune system identify foreign invaders such as viruses and bacteria and which impact a wide variety of clinical outcomes including infection and cancer.

8 Nov 2018

Researchers develop solution to ensure long-term safe storage of sensitive health data

Researchers from the Collaborative Research Center CROSSING at Technische Universität Darmstadt (Germany) have developed a solution that will ensure decades of safe storage for sensitive health data in a joint project with Japanese and Canadian partners.

8 Nov 2018

Precision medicine: Statistical methods play key role in predicting efficacy of new drugs

The aim of "precision medicine" is to devise individualized treatment strategies and therapies. Statistical methods play an important role in predicting the efficacy of drugs from clinical study data, based on patient characteristics.

8 Nov 2018

One type of Chlamydia protein manipulates human cells in two different ways

When Chlamydia trachomatis, the bacterium that causes one of the most common sexually transmitted infections worldwide, infects a human cell, it hijacks parts of the host to build protective layers around itself.

8 Nov 2018

Mutant p53 protein 'tackles' DNA guardian to drive tumor development

Melbourne scientists have discovered how tumor development is driven by mutations in the most important gene in preventing cancer, p53.

7 Nov 2018

Tracking down microRNA candidates linked to disease

What started as Ninad Oak's side project turned out into something much larger, his doctorate thesis. "The project started as my qualifying exam that I proposed at the end of my first year of graduate school," said Oak, a graduate student in molecular and human genetics in Dr. Sharon E. Plon's lab. "This was an off topic qualifying exam at the time, meaning the lab had not worked on this topic before."

7 Nov 2018

Scientists make strides in developing liquid biopsies for detecting brain tumor DNA

Scientists are making strides in developing liquid biopsies for brain tumors by detecting tumor DNA in the fluid from around the brain and spine.

7 Nov 2018

Scientists discover new details about UHRF1 protein

Epigenetic changes often play an important role in cancer, because they cause the genetic material to be read incorrectly at certain locations. Genes that are especially critical are those that control the growth and death of cells.

7 Nov 2018

Genetics can be used to predict schizophrenic patient's response to antipsychotic drugs

Genetics can be used to predict a patient's response to antipsychotic drug treatment for schizophrenia, according to a recent study by investigators at The Feinstein Institute for Medical Research. The findings were published online today in the American Journal of Psychiatry.

5 Nov 2018

New research explains how large virus shells are formed

A virus, the simplest physical object in biology, consists of a protein shell called the capsid, which protects its nucleic acid genome -- RNA or DNA. The capsid can be cylindrical or conical in shape, but more commonly it assumes an icosahedral structure, like a soccer ball.

5 Nov 2018

Genetic factors linked to obesity may lower metabolic risk

Experts believe that where on the body people store surplus fat, whether round their middle or round the liver, may be genetically determined.

2 Nov 2018

Illumina signs agreement to acquire Pacific Biosciences

Illumina, Inc. and Pacific Biosciences today announced they have signed an agreement for Illumina to acquire Pacific Biosciences at a price of $8.00 per Pacific Biosciences share in an all-cash transaction.

2 Nov 2018

Zinc can protect against oxidative stress when taken along with coffee, tea, and chocolate

Ageing and a low life expectancy are caused, at least partly, by oxidative stress. A team of researchers led by Prof. Dr. Ivana Ivanovi-Burmazovi from the Chair of Bioinorganic Chemistry at Friedrich-Alexander-Universität Erlangen-Nürnberg (FAU), together with researchers from the USA, have discovered that zinc can activate an organic molecule, helping to protect against oxidative stress.

2 Nov 2018

UCLA researchers investigate how a protein factor contributes to cancer cell migration

UCLA researchers have discovered a new protein factor that contributes to a fibroblast cell's ability to migrate to a wound and participate in its healing process. The study's results could help scientists prevent cancer cells from using the same mechanisms to move throughout the body and spread.

1 Nov 2018

Scientists decode the longest ever continuous DNA sequence

Scientists have decoded the longest continuous DNA sequence to date, measuring around 10,000 times longer than normal sequencing reads.

1 Nov 2018

Observing functional changes of cells in blood vessels may help detect early signs of atherosclerosis

A study in mice has shown that it may be possible to detect the early signs of atherosclerosis, which leads to blocked arteries, by looking at how cells in our blood vessels change their function.

1 Nov 2018

Presence of rare mutations indicates increased risk from interval breast cancers

While the presence of common breast cancer mutations was indicative of increased breast cancer risk, the presence of certain rare mutations was indicative of increased risk from interval breast cancers and death.

1 Nov 2018

Repair defect in neurons hints at possible therapy for preventing ALS

Houston Methodist researchers have discovered a repair defect in nerve cells that send messages to the brain, opening the door to a possible therapy for preventing or slowing down ALS.

1 Nov 2018

UC Scientist receives NIH grant for developing new malaria therapeutic strategies

A scientist at the University of California, Riverside, who researches the malaria-causing parasite, Plasmodium falciparum, is the principal investigator, or PI, on two grants from the National Institutes of Health, or NIH, totaling nearly $6.6 million. Funding from each grant is for five years.

1 Nov 2018

Genome News and Research

ChromDesign project trains budding scientists in 3D architecture of genome

Monash researchers provide insight into intricate peptide changes affecting immune system

Researchers develop solution to ensure long-term safe storage of sensitive health data

Precision medicine: Statistical methods play key role in predicting efficacy of new drugs

One type of Chlamydia protein manipulates human cells in two different ways

Mutant p53 protein 'tackles' DNA guardian to drive tumor development

Tracking down microRNA candidates linked to disease

Scientists make strides in developing liquid biopsies for detecting brain tumor DNA

Scientists discover new details about UHRF1 protein

Genetics can be used to predict schizophrenic patient's response to antipsychotic drugs

New research explains how large virus shells are formed

Genetic factors linked to obesity may lower metabolic risk

Illumina signs agreement to acquire Pacific Biosciences

Zinc can protect against oxidative stress when taken along with coffee, tea, and chocolate

UCLA researchers investigate how a protein factor contributes to cancer cell migration

Scientists decode the longest ever continuous DNA sequence

Observing functional changes of cells in blood vessels may help detect early signs of atherosclerosis

Presence of rare mutations indicates increased risk from interval breast cancers

Repair defect in neurons hints at possible therapy for preventing ALS

UC Scientist receives NIH grant for developing new malaria therapeutic strategies

Genetics & Genomics - Second Edition eBook

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