Aging News and Research

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Insilico Medicine and TARA Biosystems collaborate to develop novel therapies for cardiac diseases

Insilico Medicine, an artificial intelligence company developing end-to-end drug discovery pipelines for age-related diseases and TARA Biosystems, Inc. a company offering "heart-on-a-chip" tissue models for drug discovery and risk assessment applications, announced today the launch of a collaboration to discover and develop novel therapies for cardiac disease and diseases associated with cardiac muscle aging.

8 Jan 2019

New findings from a safety and feasibility clinical trial on removal of senescent cells

Mayo Clinic researchers, along with collaborators from Wake Forest School of Medicine and the The University of Texas Health Sciences Center at San Antonio, have published findings from a safety and feasibility clinical trial on the removal of senescent cells from a small group of patients with pulmonary fibrosis

7 Jan 2019

Cellular protein signal can be manipulated to favor bone building

In experiments in rats and human cells, Johns Hopkins Medicine researchers say they have added to evidence that a cellular protein signal that drives both bone and fat formation in selected stem cells can be manipulated to favor bone building.

7 Jan 2019

Study confirms increased pneumonia risk with prescription opioids

A study led by researchers at Yale University has shown that taking prescribed opioids increases the risk of pneumonia, irrespective of HIV status.

7 Jan 2019

Researchers develop mouse model to study consequences of fungal infection in the brain

Fungal infections are emerging as a major medical challenge, and a team led by researchers at Baylor College of Medicine has developed a mouse model to study the short-term consequences of fungal infection in the brain.

4 Jan 2019

Tideswell-AGS-ADGAP ELIA program offers a new take on learning to lead for experts in geriatrics

Experts in geriatrics, the healthcare specialty dedicated to our needs as we age, are making more than a New Year's resolution to continue improving our care as we grow older.

4 Jan 2019

Mediterranean diet is the best diet there is

Diets come and go and have their time in the trending list. The U.S. News and World Report has however confirmed that the healthiest diet at present is the Mediterranean diet.

3 Jan 2019

New medications provide better treatment for alcohol use disorders, chronic pain, mood disorders

Helping people with addictions has become a research passion for Purdue University's Richard van Rijn, who is leading a team to make drug discoveries to support millions around the world dealing with alcohol use disorders, chronic pain and mood disorders.

3 Jan 2019

Senescent cells in the brain shown to cause obesity-related anxiety

Researchers have shown that obesity increases the level of semi-dormant senescent cells in the brain, which give rise to anxiety-like behaviors.

3 Jan 2019

Alzheimer’s Disease: Learning from the Past, Looking to the Future

An interview with Dr. Lloyd Tran, discussing the major barriers to Alzheimer’s research and development over the past 40 years.

From Alzheimer International Society 3 Jan 2019

Hyperactive immune system implicated in aging brain disorders

In a study of fruit flies, NIH scientists suggested that the body's immune system may play a critical role in the damage caused by aging brain disorders. The results are based on experiments in which the researchers altered the activity of Cdk5, a gene that preclinical studies have suggested is important for early brain development and may be involved in neurodegenerative diseases, such as ALS, Alzheimer's and Parkinson's disease.

2 Jan 2019

New research could help restore youthful characteristics

If only we could keep our bodies young, healthy and energetic, even as we attain the wisdom of our years. New research at the Weizmann Institute of Science suggests this dream could be at least partly obtainable in the future.

2 Jan 2019

Older adults care about strangers' welfare in financial decision-making, study finds

A recent study by researchers from the National University of Singapore found that when it comes to making financial decisions under risk, older adults will regard the financial outcomes of others' as their own and make choices that they would have selected for themselves.

30 Dec 2018

Insilico to present 'AI-powered end-to-end pipelines for drug discovery' at Longevity Therapeutics 2019

Insilico Medicine, a Rockville-based company developing the end-to-end drug discovery pipeline utilizing the next generation artificial intelligence, will present its latest results in modern and next-generation AI for Drug Discovery at The Longevity Therapeutics 2019 in San Francisco, 30 of January.

30 Dec 2018

Genetically diverse mouse models improves usability for precision medicine for Alzheimer's

Incorporating genetic diversity into a mouse model of Alzheimer's disease resulted in greater overlap with the genetic, molecular and clinical features of this pervasive human disease, according to a study funded by the National Institute on Aging, part of the National Institutes of Health.

28 Dec 2018

Study explains effects of aging on endothelial health and vascular regenerative capacity

The endothelium plays an important role in cardiovascular regulation, from blood flow to platelet aggregation, immune cell infiltration and demargination.

28 Dec 2018

Late-life mortality plateaus can result from diverse statistical errors

Human error, not human biology, largely accounts for the apparent decline of mortality among the very old, according to a new report publishing on December 20 in the open-access journal PLOS Biology by Saul Newman of Australia National University in Canberra.

27 Dec 2018

Study uncovers how skin ages, loses fat and immunity

Dermal fibroblasts are specialized cells deep in the skin that generate connective tissue and help the skin recover from injury. Some fibroblasts have the ability to convert into fat cells that reside under the dermis, giving the skin a plump, youthful look and producing a peptide that plays a critical role in fighting infections.

27 Dec 2018

Scientists suggest need for new approach to confront side effects of common anti-cancer therapy

Results of a new study by neuroscientists at the University of Massachusetts Amherst and the University of Toronto suggest that a new treatment approach is needed - and how this may be possible - to address adverse effects of aromatase inhibitors, drugs commonly prescribed to both men and women to prevent recurrence of estrogen-positive breast cancer.

27 Dec 2018

Neuronal cell death in Alzheimer's disease may actually not be a bad thing, shows study

For the first time, scientists at the Champalimaud Centre for the Unknown, in Lisbon, Portugal, have shown that neuronal cell death in Alzheimer's disease may actually not be a bad thing - on the contrary, it may be the result of a cell quality control mechanism trying to protect the brain from the accumulation of malfunctioning neurons.

27 Dec 2018

Aging News and Research

Insilico Medicine and TARA Biosystems collaborate to develop novel therapies for cardiac diseases

New findings from a safety and feasibility clinical trial on removal of senescent cells

Cellular protein signal can be manipulated to favor bone building

Study confirms increased pneumonia risk with prescription opioids

Researchers develop mouse model to study consequences of fungal infection in the brain

Tideswell-AGS-ADGAP ELIA program offers a new take on learning to lead for experts in geriatrics

Mediterranean diet is the best diet there is

New medications provide better treatment for alcohol use disorders, chronic pain, mood disorders

Senescent cells in the brain shown to cause obesity-related anxiety

Alzheimer’s Disease: Learning from the Past, Looking to the Future

Hyperactive immune system implicated in aging brain disorders

New research could help restore youthful characteristics

Older adults care about strangers' welfare in financial decision-making, study finds

Insilico to present 'AI-powered end-to-end pipelines for drug discovery' at Longevity Therapeutics 2019

Genetically diverse mouse models improves usability for precision medicine for Alzheimer's

Study explains effects of aging on endothelial health and vascular regenerative capacity

Late-life mortality plateaus can result from diverse statistical errors

Study uncovers how skin ages, loses fat and immunity

Scientists suggest need for new approach to confront side effects of common anti-cancer therapy

Neuronal cell death in Alzheimer's disease may actually not be a bad thing, shows study

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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