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New drug marks cancer cells for destruction by the immune system

Tumor cells are notoriously good at evading the human immune system; they put up physical walls, wear disguises and handcuff the immune system with molecular tricks.

13 Sep 2022

Treating the cerebrospinal fluid to protect the brain from chemotherapy's toxic effects

Up to three quarters of patients receiving cancer chemotherapy suffer from "chemo brain" - a long-term side effect that makes it harder to remember things, maintain attention, and learn new information. When it strikes children, whose brains are still developing, their schoolwork and self-esteem may suffer.

13 Sep 2022

AI system can quickly and automatically evaluate chest X-rays for TB

An artificial intelligence system detects tuberculosis (TB) in chest X-rays at a level comparable to radiologists, according to a study published in Radiology, a journal of the Radiological Society of North America.

13 Sep 2022

Study identifies mechanism behind 'cytokine storm' in COVID-19 patient lungs

A new study by HSS Research Institute scientists identifies a mechanism by which SARS-CoV-2 induces the inflammatory response in COVID-19 patient lungs, so-called "cytokine storm", that can lead to lasting tissue damage and poor patient outcomes.

13 Sep 2022

How effective is vitamin D supplementation in COVID-19?

The current paper addresses the considerable evidence now supporting the efficacy of vitamin D in COVID-19, as well as its safety.

13 Sep 2022

MSK researchers reveal a promising treatment option for bladder cancer patients

Researchers from Memorial Sloan Kettering Cancer Center (MSK) shared a promising treatment option for bladder cancer patients today at The European Society for Medical Oncology (ESMO) Congress 2022.

13 Sep 2022

New long-term opioid use associated with a heightened risk of death, study finds

New long term use of opioids to quell pain after lung cancer surgery is linked to a 40% heightened risk of death from any cause within the next 2 years, finds research published online in the journal Regional Anesthesia & Pain Medicine.

13 Sep 2022

Saline nasal irrigation after COVID-19 diagnosis reduces hospitalization

Starting twice daily flushing of the mucus-lined nasal cavity with a mild saline solution soon after testing positive for COVID-19 can significantly reduce hospitalization and death, investigators report.

13 Sep 2022

Antibiotics accelerate metastatic bone growth in mice with melanoma by depleting intestinal flora

The use of broad-spectrum antibiotics in mice with malignant melanoma, an aggressive form of skin cancer, accelerated their metastatic bone growth, likely because the drugs depleted the mice's intestinal flora and weakened their immune response, according to a new study by researchers at Emory University in Atlanta.

12 Sep 2022

Study identifies new therapeutic target against lung adenocarcinoma

The TIMP-1 protein levels in both tissues and blood have been repeatedly associated with a poor prognosis in lung cancers, but its role in this cancer process was, to date, unknown.

12 Sep 2022

COVID-19 drugs persist through wastewater treatment, may negatively affect aquatic organisms

Certain drugs used to treat COVID-19 patients - including remdesivir, dexamethasone and antibiotics for associated bacterial infections - persist through wastewater treatment and may occur in waterways at levels high enough to negatively affect aquatic organisms, according to a new study led by researchers at Penn State.

12 Sep 2022

Small molecule inhibitor found to be effective against SARS-CoV-2 variants

In a new study, researchers developed RK-33, a small molecule inhibitor of DDX3, and evaluated its efficacy against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants of concern (VOCs).

12 Sep 2022

‘An Arm and a Leg’: The new cap on Medicare drug costs

On a Sunday afternoon in August, health services researcher Stacie Dusetzina was sitting alone in her office at Vanderbilt University, watching C-SPAN and crying.

12 Sep 2022

While inflation takes a toll on seniors, billions of dollars in benefits go unused

Millions of older adults are having trouble making ends meet, especially during these inflationary times. Yet many don't realize help is available, and some notable programs that offer financial assistance are underused.

12 Sep 2022

Patients with high-risk melanoma benefit from immunotherapy prior to surgery

Patients with high-risk melanoma who received the immunotherapy drug pembrolizumab both before and after surgery to remove cancerous tissue had a significantly lower risk of their cancer recurring than similar patients who received the drug only after surgery.

12 Sep 2022

Study shortlists potential drug repurposing candidates to treat symptoms in ASD

Can you teach an old drug new tricks? Although drug treatments for the core symptoms of autism spectrum disorder (ASD) are not currently available, could an existing drug provide a new treatment, even if it previously had no association with ASD? This was the question asked by a new study in the journal Frontiers in Pharmacology. The researchers used a computer model that encompasses proteins involved in ASD and the way they interact.

12 Sep 2022

Tumor-infiltrating lymphocytes therapy treats cancers at a large scale

A novel treatment strategy with personalized cell therapy significantly improves progression-free survival compared to standard immunotherapy in patients with advanced melanoma, according to ground-breaking results reported at the ESMO Congress 2022 from the phase 3 M14TIL trial.

12 Sep 2022

ACTG announces the initiation of trial evaluating the safety and efficacy of monkeypox treatment

The AIDS Clinical Trials Group (ACTG), the largest global HIV research network, which expanded its focus to conduct research into COVID-19, today announced the initiation of STOMP (Study of Tecovirimat for Human Monkeypox Virus), or A5418, a phase 3, randomized, placebo-controlled, double-blind trial evaluating the safety and efficacy of tecovirimat for the treatment of human monkeypox.

9 Sep 2022

Novel antifungal medications urgently needed to control COVID-19-associated fungal infections

Every day we inhale thousands of potentially pathogenic fungal spores, but our immune system simply eliminates them.

9 Sep 2022

Weill Cornell Medicine receives $5 million NIH grant for next generation TB research

Weill Cornell Medicine has been awarded a five-year, $5 million grant from the National Institutes of Allergy and Infectious Diseases of the National Institutes of Health to establish a new multi-institutional center for tuberculosis (TB) research and training the next generation of TB investigators.

9 Sep 2022

Drugs News and Research

New drug marks cancer cells for destruction by the immune system

Treating the cerebrospinal fluid to protect the brain from chemotherapy's toxic effects

AI system can quickly and automatically evaluate chest X-rays for TB

Study identifies mechanism behind 'cytokine storm' in COVID-19 patient lungs

How effective is vitamin D supplementation in COVID-19?

MSK researchers reveal a promising treatment option for bladder cancer patients

New long-term opioid use associated with a heightened risk of death, study finds

Saline nasal irrigation after COVID-19 diagnosis reduces hospitalization

Antibiotics accelerate metastatic bone growth in mice with melanoma by depleting intestinal flora

Study identifies new therapeutic target against lung adenocarcinoma

COVID-19 drugs persist through wastewater treatment, may negatively affect aquatic organisms

Small molecule inhibitor found to be effective against SARS-CoV-2 variants

‘An Arm and a Leg’: The new cap on Medicare drug costs

While inflation takes a toll on seniors, billions of dollars in benefits go unused

Patients with high-risk melanoma benefit from immunotherapy prior to surgery

Study shortlists potential drug repurposing candidates to treat symptoms in ASD

Tumor-infiltrating lymphocytes therapy treats cancers at a large scale

ACTG announces the initiation of trial evaluating the safety and efficacy of monkeypox treatment

Novel antifungal medications urgently needed to control COVID-19-associated fungal infections

Weill Cornell Medicine receives $5 million NIH grant for next generation TB research

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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