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Zika virus vaccine shows promise for treatment of fatal glioblastoma

An international team of researchers has successfully deployed a Zika virus vaccine to target and kill human glioblastoma brain cancer stem cells, which had been transplanted into mice.

18 Sep 2018

Researchers analyze how exposure to silver nanoparticles affects zebrafish

Silver nanoparticles are increasingly being used in consumer products, such as clothing and personal care products, in the medical and pharmaceutical industry, and in the food industry.

18 Sep 2018

Brigham Genomic Medicine program unravels 30 medical mysteries

A table in a recently published paper tells the story of 30 families who have, sometimes after years of searching, finally received an answer about the condition that has plagued one or more family members.

18 Sep 2018

Researchers use CRISPR to identify gene that helps cells resist flavivirus infection

UT Southwestern researchers today report the first use of CRISPR genome-wide screening to identify a gene that helps cells resist flavivirus infection. That nasty class of pathogens includes West Nile virus, dengue fever, Zika virus, and yellow fever.

18 Sep 2018

Machine learning program could distinguish between two lung cancer types

A new computer program can analyze images of patients' lung tumors, specify cancer types, and even identify altered genes driving abnormal cell growth, a new study shows.

17 Sep 2018

Twice-a-year MRI more effective than mammograms for women with genetic breast cancer risk

Getting magnetic resonance imaging scans twice a year instead of one annual mammogram is far more effective at detecting early breast cancers in young women with a high-risk genetic profile than mammograms alone, according to a research team based at the University of Chicago Medicine and the University of Washington, Seattle.

14 Sep 2018

UTA scientist to provide new insights on the role of 'jumping genes'

A biology researcher at The University of Texas at Arlington will be using the high-tech tools provided by the North Texas Genome Center to shed light on the role of 'jumping genes'.

14 Sep 2018

Discovery of key mechanism may lead to more functional skin grafts for burn victims

University of Colorado Boulder researchers have discovered a key mechanism by which skin begins to develop in embryos, shedding light on the genetic roots of birth defects like cleft palate and paving the way for development of more functional skin grafts for burn victims.

14 Sep 2018

Study provides complete picture of HPV virus-head and neck cancer connections

Human papillomavirus is widely known to cause nearly all cases of cervical cancer. However, you might not know that HPV also causes 70 percent of oropharyngeal cancer, a subset of head and neck cancers that affect the mouth, tongue, and tonsils.

12 Sep 2018

Highly personalized approach may help immune cells to eliminate melanoma

With new immunotherapy treatments for melanoma, recovery rates have risen dramatically, in some cases to around 50%.

12 Sep 2018

Study finds overlapping copy number variations in Japanese patients with autism and schizophrenia

Common genetic variants may underlie autism spectrum disorder and schizophrenia across human populations, according to a study appearing September 11th in the journal Cell Reports.

12 Sep 2018

New insight on mechanics of rotavirus could open up avenues for effective treatments

Researchers have provided new insight on the mechanics of a virus that causes severe diarrhea and sickness in young children, according to a report published in eLife.

12 Sep 2018

Penn receives NIH grant to create Center for Sub-Cellular Genomics

The five-year, $10.5 million grant from the NIH is the first CEGS awarded to Penn and funds the creation of the Center for Sub-Cellular Genomics.

12 Sep 2018

Microbe researcher Jessica Metcalf wins early-career award

The associate professor in the Department of Animal Sciences is fascinated by our relationship with the trillions of invisible, living organisms inhabiting our bodies, and most notably, our guts.

12 Sep 2018

New framework combines three existing methods to find cancer cell mutations

Cancer cells often have mutations in their DNA that can give scientists clues about how the cancer started or which treatment may be most effective. Finding these mutations can be difficult, but a new method may offer more complete, comprehensive results.

10 Sep 2018