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Penn Medicine scientists identify stem-like 'progenitor' cell that produces heart muscle cells

Future therapies for failing hearts are likely to include stem-like cells and associated growth factors that regenerate heart muscle. Scientists from the Perelman School of Medicine at the University of Pennsylvania have just taken an important step towards that future by identifying a stem-like "progenitor" cell that produces only heart muscle cells.

26 Jun 2015

E2F4 biomarker can help predict prognosis and response to BCG therapy in bladder cancer

Investigators from Dartmouth's Norris Cotton Cancer Center harnessed genomic data to discover that the previously identified E2F4 signature in breast cancer can be utilized to predict prognosis and response to therapy in bladder cancer.

25 Jun 2015

Cognitive behavioural therapy can change brain function of people with Tourette syndrome

In addition to its effect on chronic tics, cognitive behavioural therapy (CBT) can change the brain function of people with Tourette syndrome.

25 Jun 2015

Cell transplantation researchers successfully treat laboratory rats modeled with severe burns

Cell transplantation researchers have successfully used bone marrow-derived mesenchymal stromal cells (MSCs) to treat a variety of diseases and conditions. Now, using injections of MSCs, a research team in Brazil has successfully treated laboratory rats modeled with severe burns.

25 Jun 2015

Sugar-gobbling enzyme helps restore normal function in heart muscles of diabetic rats

Working with heart muscle cells from diabetic rats, scientists at Johns Hopkins have located what they say is the epicenter of mischief wreaked by too much blood sugar and used a sugar-gobbling enzyme to restore normal function in the glucose-damaged cells of animal heart muscles.

25 Jun 2015

Novogen’s chemotherapy drug Anisina proves as effective anti-cancer agent in animals

US-Australian drug discovery company, Novogen Limited announced today that its candidate cytotoxic chemotherapy drug, Anisina, has proved an effective anti-cancer agent in animals, the result of which it now has been fast-tracked by the Company to come into the clinic.

24 Jun 2015

Johns Hopkins scientists use experimental therapy to reverse progression of atherosclerosis in rodents

In what may be a major leap forward in the quest for new treatments of the most common form of cardiovascular disease, scientists at Johns Hopkins report they have found a way to halt and reverse the progression of atherosclerosis in rodents by loading microscopic nanoparticles with a chemical that restores the animals’ ability to properly handle cholesterol.

24 Jun 2015

Stanford researchers find how neurons work together to control movement in people with paralysis

Stanford University researchers studying how the brain controls movement in people with paralysis, related to their diagnosis of Lou Gehrig's disease, have found that groups of neurons work together, firing in complex rhythms to signal muscles about when and where to move.

24 Jun 2015

Israeli researchers establish novel optogenetic method for cardiac pacing and resynchronization

Israeli researchers have successfully established a new approach for pacing the heart and synchronizing its mechanical activity without the use of a conventional electrical pacemaker. This novel biologic strategy employs light-sensitive genes that can be injected into the heart and then activated by flashes of blue light.

23 Jun 2015

Study: High-normal BP in young adults spells heart failure risk in later life

Mild elevations in blood pressure considered to be in the upper range of normal during young adulthood can lead to subclinical heart damage by middle age -- a condition that sets the stage for full-blown heart failure, according to findings of a federally funded study led by scientists at Johns Hopkins.

23 Jun 2015

Ontario announces $25 million investment to support new treatments for people with chronic diseases

Ontario is investing $25 million over five years to support new treatments and therapies for people living with chronic diseases, such as cancer, multiple sclerosis and diabetes.

23 Jun 2015

UT Southwestern scientists devise new technique to identify cell that replenishes adult heart muscle

Regenerative medicine researchers at UT Southwestern Medical Center have identified a cell that replenishes adult heart muscle by using a new cell lineage-tracing technique they devised.

23 Jun 2015

New research could help reverse side effects of acetaminophen overdose

New research could help reverse deadly side effects caused by excessive doses of the drug acetaminophen, the major ingredient in Tylenol and many other over-the-counter and prescription medicines.

23 Jun 2015

Isis Pharmaceuticals provides update on ISIS-SMN Rx Phase 2 study in children with SMA

Isis Pharmaceuticals, Inc. today provided an update on children with spinal muscular atrophy (SMA) who have completed the open-label, Phase 2 multiple-dose study of ISIS-SMN Rx and are continuing to receive treatment in an open-label extension (OLE) study.

22 Jun 2015

Small intestine causes chronic inflammation in obese patients

Obesity is caused by numerous and complex factors, some of which are as yet unsuspected. Scientists from the CNRS, INSERM, UPMC and Université Paris Descartes, working with research clinicians from Paris Public Hospitals (AP-HP) have now shown that severe obesity is accompanied by inflammation of the small intestine and enhanced immune response in that region.

22 Jun 2015

New Christian Doppler Laboratory for Clinical Molecular MR Imaging opens at MedUni Vienna

Today the new Christian Doppler Laboratory for Clinical Molecular MR Imaging (MOLIMA) was opened at the University Clinic of Radiology and Nuclear Medicine at MedUni Vienna. Its aim is to bring about a significant improvement in the prognosis or course of a disease. The research institute, which is funded by the Federal Ministry of Science, Research and Economy, develops high-resolution, quantitative imaging techniques to allow disease to be identified at an even earlier stage.

19 Jun 2015

Cosmetic surgery could improve lives of people with facial paralysis

A cosmetic surgery that uses injections of hyaluronic acid to make lips appear fuller could also improve the lives of people with facial paralysis, according to results of a small study by researchers at Johns Hopkins and Stanford universities.

19 Jun 2015

Researchers explore the science of exosomes in heart repair

A little more than a decade ago, researchers discovered that all cells secrete tiny communications modules jammed with an entire work crew of messages for other cells. Today, a team of researchers, led by stem cell researcher Raj Kishore, PhD, Director of the Stem Cell Therapy Program at the Center for Translational Medicine at Temple University School of Medicine, is harnessing the communications vesicles excreted by stem cells and using them to induce the damaged heart to repair itself.

19 Jun 2015

Vinculin protein levels increase with age to alter shape, performance of cardiac muscle cells

The human heart makes precious few new cells but manages to generate billions of life-sustaining beats as it grows old.

18 Jun 2015

High fructose consumption can lead to uncontrolled growth of cardiomyocytes, heart attack

'Walk through any supermarket and take a look at the labels on food products, and you'll see that many of them contain fructose, often in the form of sucrose (table sugar)' -- that's how Wilhelm Krek, professor for cell biology at ETH Zurich's Institute for Molecular Health Sciences, summarises the problem with today's nutrition.

18 Jun 2015

Muscle News and Research

Penn Medicine scientists identify stem-like 'progenitor' cell that produces heart muscle cells

E2F4 biomarker can help predict prognosis and response to BCG therapy in bladder cancer

Cognitive behavioural therapy can change brain function of people with Tourette syndrome

Cell transplantation researchers successfully treat laboratory rats modeled with severe burns

Sugar-gobbling enzyme helps restore normal function in heart muscles of diabetic rats

Novogen’s chemotherapy drug Anisina proves as effective anti-cancer agent in animals

Johns Hopkins scientists use experimental therapy to reverse progression of atherosclerosis in rodents

Stanford researchers find how neurons work together to control movement in people with paralysis

Israeli researchers establish novel optogenetic method for cardiac pacing and resynchronization

Study: High-normal BP in young adults spells heart failure risk in later life

Ontario announces $25 million investment to support new treatments for people with chronic diseases

UT Southwestern scientists devise new technique to identify cell that replenishes adult heart muscle

New research could help reverse side effects of acetaminophen overdose

Isis Pharmaceuticals provides update on ISIS-SMN Rx Phase 2 study in children with SMA

Small intestine causes chronic inflammation in obese patients

New Christian Doppler Laboratory for Clinical Molecular MR Imaging opens at MedUni Vienna

Cosmetic surgery could improve lives of people with facial paralysis

Researchers explore the science of exosomes in heart repair

Vinculin protein levels increase with age to alter shape, performance of cardiac muscle cells

High fructose consumption can lead to uncontrolled growth of cardiomyocytes, heart attack

Industry Focus eBook - Forensics & toxicology (2nd edition) eBook

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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