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Cannabis legalization likely to reduce conventional pharmaceutical sales by billions of dollars

Researchers from California Polytechnic State University and The University of New Mexico find that stock market investors predict cannabis legalization will reduce conventional pharmaceutical sales by billions of dollars.

2 Sep 2022

Depletion of reactive astrocytes regresses glioblastoma

A groundbreaking study at Tel Aviv University effectively eradicated glioblastoma, a highly lethal type of brain cancer. The researchers achieved the outcome using a method they developed based on their discovery of two critical mechanisms in the brain that support tumor growth and survival: one protects cancer cells from the immune system, while the other supplies the energy required for rapid tumor growth. The work found that both mechanisms are controlled by brain cells called astrocytes, and in their absence, the tumor cells die and are eliminated.

2 Sep 2022

Globalization and cessation of smallpox vaccination are influencing monkeypox spread

A recent review by Barbara S. Schnierle of the Paul-Ehrlich-Institut, Germany, and published in the journal Viruses summarized the existing knowledge about MPXV, the disease it causes, and the strategies to curb its spread.

1 Sep 2022

Study opens a window of opportunity to design RAF1 degraders against lung adenocarcinomas

One of the main challenges in oncology is the development of drugs against KRAS oncogenes. These oncogenes -genes that cause cancer when mutated - are responsible for a quarter of all human cancers, including the three tumor types with the highest mortality rates: lung adenocarcinoma, colorectal carcinoma and pancreatic ductal adenocarcinoma.

1 Sep 2022

Dolutegravir-based regimen more effective for treating pregnant people with HIV-1

Dolutegravir-based antiretroviral therapies (ART) for HIV-1 are more effective for pregnant people than some other ART regimens commonly used in the U.S. and Europe, according to a study led by Harvard T.H. Chan School of Public Health researchers.

1 Sep 2022

Researchers identify how some cancer cells cheat treatment-induced cell death

Scientists at St. Jude Children's Research Hospital have identified how some cancer cells cheat treatment-induced cell death.

1 Sep 2022

New kind of synapse discovered in neurons’ tiny hairs

Scientists at HHMI's Janelia Research Campus have discovered a new kind of synapse in the tiny hairs on the surface of neurons.

1 Sep 2022

Study suggests strategies to bolster the administration of clot-busting drugs

Venous thromboembolism (VTE) is a potentially deadly condition in which a blood clot (known as a deep vein thrombosis [DVT]) forms in the deep veins of the leg, groin or arm and may dislodge.

1 Sep 2022

Inhibiting a key metabolic enzyme selectively kills melanoma cells and stops tumor growth

Researchers at Sanford Burnham Prebys, led by Ze'ev Ronai, Ph.D., have shown for the first time that inhibiting a key metabolic enzyme selectively kills melanoma cells and stops tumor growth.

1 Sep 2022

New study suggests metformin is associated with less severe COVID-19 across prediabetic individuals

In a new study, researchers illustrated that metformin was associated with decreased coronavirus disease 2019 (COVID-19) severity among prediabetic patients.

1 Sep 2022

Intranasally delivered neutralizing antibody protects against SARS-CoV-2 Omicron and Delta variants

The current study focused on the ability of this nmAb to neutralize Delta, Omicron, and other VOCs, as well as its efficacy when given by the intranasal route in an animal model.

1 Sep 2022

The war in Ukraine and resulting massive population displacement has enhanced epidemic typhus risk

The ongoing war in Ukraine has caused massive destruction in the region, enhancing the risk of epidemic typhus.

31 Aug 2022

The most recent evidence about phylogenesis, pathogenesis, prevention, and treatment for monkeypox

A new review sheds light on the origins of this virus and recently acquired knowledge about its disease mechanism and the preventive and therapeutic measures appropriate in this situation.

31 Aug 2022

Research provides a major step forward to growing human kidney in a dish

Kidney disease affects one in nine adults globally and the incidence of kidney failure is steadily rising around the world.

30 Aug 2022

Research shows how sensor-based health monitoring could help tackle age-related health problems

Specific changes in our movement patterns can be indicators of several health problems: For instance, decrease in strength often correlates with risk of falls, mild cognitive impairment, depression, sleep problems, respiratory problems, cardiac arrhythmias and increasing myocardial weakness or worsening of a COVID-19 infection.

30 Aug 2022

Drugs News and Research

Cannabis legalization likely to reduce conventional pharmaceutical sales by billions of dollars

Depletion of reactive astrocytes regresses glioblastoma

Globalization and cessation of smallpox vaccination are influencing monkeypox spread

Study opens a window of opportunity to design RAF1 degraders against lung adenocarcinomas

Dolutegravir-based regimen more effective for treating pregnant people with HIV-1

Researchers identify how some cancer cells cheat treatment-induced cell death

New kind of synapse discovered in neurons’ tiny hairs

Study suggests strategies to bolster the administration of clot-busting drugs

Inhibiting a key metabolic enzyme selectively kills melanoma cells and stops tumor growth

New study suggests metformin is associated with less severe COVID-19 across prediabetic individuals

Intranasally delivered neutralizing antibody protects against SARS-CoV-2 Omicron and Delta variants

The war in Ukraine and resulting massive population displacement has enhanced epidemic typhus risk

The most recent evidence about phylogenesis, pathogenesis, prevention, and treatment for monkeypox

Research provides a major step forward to growing human kidney in a dish

Research shows how sensor-based health monitoring could help tackle age-related health problems

Naturally occurring compound possesses antibacterial activity against several microorganisms

Using human tissue models to improve treatment and diagnosis of heart attacks

EEG tests reveal fentanyl's effects on the brain

Using deep learning to guide the selection of chemotherapy after surgery for colorectal cancer patients

Gothenburg scientists discover possible new cancer treatment target

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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