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AstraZeneca, Inserm to investigate new therapeutic approaches to type 2 diabetes, CKD

AstraZeneca today announced a three-year research collaboration with the French National Institute of Health and Medical Research (Inserm) to investigate new therapeutic approaches totype 2 diabetes and Chronic Kidney Disease.

18 Jun 2015

New article shows taxonomic classification of rare genetic bone disorders based on metabolic phenotypes

An International Osteoporosis Foundation Working Group on Skeletal Rare Diseases has published a new classification of rare genetic metabolic bone disorders (RGMBDs) according to their metabolic pathogenesis.

18 Jun 2015

Australian researchers discover gene involved in muscular dystrophy

Australian researchers have made a critical discovery about a gene involved in muscular dystrophy that could lead to future therapies for the currently untreatable disease.

18 Jun 2015

New tissue 'scaffold' technology could one day help produce large organs

Scientists have developed a new tissue 'scaffold' technology that could one day enable the engineering of large organs. Research led by the Universities of Bristol and Liverpool has shown that it is possible to combine cells with a special scaffold to produce living tissue in the laboratory. It is hoped this can then be implanted into patients as a way of replacing diseased parts of the body.

17 Jun 2015

Allergan agrees to acquire KYTHERA Biopharmaceuticals for $2.1 billion

Allergan plc, a leading global pharmaceutical company, and KYTHERA Biopharmaceuticals, Inc., a biopharmaceutical company focused on the discovery, development and commercialization of novel prescription products for the aesthetic medicine market, today announced that they have entered into a definitive agreement under which Allergan has agreed to acquire KYTHERA in a cash and equity transaction valued at $75 per KYTHERA share, or approximately $2.1 billion.

17 Jun 2015

Women with significant depressive symptoms have lower levels of klotho hormone

Women under chronic stress have significantly lower levels of klotho, a hormone that regulates aging and enhances cognition, researchers at UC San Francisco have found in a study comparing mothers of children on the autism spectrum to low-stress controls.

17 Jun 2015

CyMedica Orthopedics closes $11.5 million Series A financing

CyMedica Orthopedics, Inc. announced today that it has closed an extension to its Series A financing. The Series A financing was led by investors Research Corporation Technologies, Inc., a Tucson-based venture capital firm, and California Technology Ventures, LLC, a Pasadena-based venture capital fund. The financing also included participation from existing investor Aphelion Capital (Mill Valley, CA) and the founding group of investors.

16 Jun 2015

Taiho, Servier sign exclusive license agreement to develop and commercialize TAS-102 drug

Taiho Pharmaceutical Co., Ltd.(Japan) and Servier (France) announced on June 15 that they have entered into an exclusive license agreement on June 12, 2015 for the development and commercialization of TAS-102 (nonproprietary names: trifluridine and tipiracil hydrochloride) in Europe and other countries.

15 Jun 2015

People with rheumatoid arthritis less likely to benefit from hepatitis B vaccine

The results of a study presented today at the European League Against Rheumatism Annual Congress (EULAR 2015) Press Conference showed that people with rheumatoid arthritis (RA) are less likely to be protected by hepatitis B vaccination than the general population.

14 Jun 2015

Experimental drug improves failing heart's function

An experimental drug improves the ability of heart muscle cells damaged by heart failure to pump blood, according to the results of a study led by Icahn School of Medicine at Mount Sinai researchers and published online today in Nature Communications.

14 Jun 2015

New noninvasive brain stimulator may help tamp down Parkinson's symptoms at home

Parkinson's disease patients whose symptoms such as tremor, muscle stiffness and slowed movement make it tough to hold an eating utensil steady have few options for relief outside of a hospital or clinic. Medication can help, but over time it tends to become less effective.

12 Jun 2015

Isis Pharmaceuticals provides update on ISIS-SMN Rx Phase 2 clinical study in infants with Type I SMA

Isis Pharmaceuticals, Inc. today provided an update on its ongoing open-label Phase 2 clinical study of ISIS-SMN Rx in infants with Type I spinal muscular atrophy (SMA).

11 Jun 2015

Study reveals surgical consequences of severe obesity

Research from the University of Alberta's Faculty of Medicine & Dentistry is revealing the heavy surgical consequences of severe obesity.

11 Jun 2015

INS announces winners of inaugural best abstract competition at 12th World Congress

The International Neuromodulation Society (INS) announced winners today of its inaugural best abstract competition at the 12th World Congress in Montreal.

10 Jun 2015

Rapid cooling procedures prior to catheterization reduce extent of myocardial infarction

After an acute myocardial infarction, patients treated with rapid lowering of body temperature by combined cold saline infusion and endovascular cooling had less heart muscle damage and reduced incidence of heart failure. Therapeutic hypothermia was especially protective against heart muscle damage in patients with a large area of myocardium at risk according to an analysis of two clinical trials published in Therapeutic Hypothermia and Temperature Management, a peer-reviewed journal from Mary Ann Liebert, Inc., publishers.

10 Jun 2015

Children undergoing deep brain stimulation for generalized dystonia experience better outcomes

Children and adolescents who received deep brain stimulation for generalized dystonia maintained significant symptom relief for up to eight years, according to a study presented today at the 12th World Congress of the International Neuromodulation Society.

10 Jun 2015

New microfluidic chip could save millions of euros in drug development costs

Scientists in an EU-supported project have developed a microfluidic chip that simultaneously analyses the reactions of several human organ tissues when they come into contact with candidates for new drugs.

10 Jun 2015

Star-shaped brain cells control cerebral blood flow and blood pressure

A star-shaped brain cell called an astrocyte appears to help keep blood pressure and blood flow inside the brain on a healthy, even keel, scientists report.

10 Jun 2015

Control systems have potential to improve function of powered leg prostheses

A control system that incorporated electrical signals generated during muscle contractions and gait information resulted in improved real-time control of a powered prosthetic leg for different modes of walking (such as on level ground or descending stairs), according to a study in the June 9 issue of JAMA, a theme issue on the Americans with Disabilities Act.

10 Jun 2015

Stem cell transplant restores sensory functions in injured spinal cord

New research from Uppsala University shows promising progress in the use of stem cells for treatment of spinal cord injury. The results, which are published in the scientific journal Scientific Reports, show that human stem cells that are transplanted to the injured spinal cord contribute to restoration of some sensory functions.

10 Jun 2015

Muscle News and Research

AstraZeneca, Inserm to investigate new therapeutic approaches to type 2 diabetes, CKD

New article shows taxonomic classification of rare genetic bone disorders based on metabolic phenotypes

Australian researchers discover gene involved in muscular dystrophy

New tissue 'scaffold' technology could one day help produce large organs

Allergan agrees to acquire KYTHERA Biopharmaceuticals for $2.1 billion

Women with significant depressive symptoms have lower levels of klotho hormone

CyMedica Orthopedics closes $11.5 million Series A financing

Taiho, Servier sign exclusive license agreement to develop and commercialize TAS-102 drug

People with rheumatoid arthritis less likely to benefit from hepatitis B vaccine

Experimental drug improves failing heart's function

New noninvasive brain stimulator may help tamp down Parkinson's symptoms at home

Isis Pharmaceuticals provides update on ISIS-SMN Rx Phase 2 clinical study in infants with Type I SMA

Study reveals surgical consequences of severe obesity

INS announces winners of inaugural best abstract competition at 12th World Congress

Rapid cooling procedures prior to catheterization reduce extent of myocardial infarction

Children undergoing deep brain stimulation for generalized dystonia experience better outcomes

New microfluidic chip could save millions of euros in drug development costs

Star-shaped brain cells control cerebral blood flow and blood pressure

Control systems have potential to improve function of powered leg prostheses

Stem cell transplant restores sensory functions in injured spinal cord

Industry Focus eBook - Forensics & toxicology (2nd edition) eBook

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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