Infectious Diseases News and Research

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Researchers reveal how C. difficile wreaks havoc on guts, causes life-threatening diseases

In a new paper in the journal Infection and Immunity, the researchers lay out for the first time exactly how C. difficile wreaks havoc on the guts of animals in a short time, and causes severe diarrhea and life-threatening disease in humans.

19 Feb 2015

HIV Prevention Trials Network launches two phase 2 studies to evaluate new HIV drugs

The HIV Prevention Trials Network has launched two new phase 2 studies, HPTN 076 and HPTN 077, which are designed to evaluate new drugs to protect people from getting infected with HIV.

19 Feb 2015

Natalizumab drug helps scientists confirm how 'viral reservoirs' form in HIV patients

A drug used to treat patients with Crohn's disease and multiple sclerosis has helped scientists confirm how "viral reservoirs" form in patients living with HIV and also proven effective in animal trials at blocking the pathways to those reservoirs in the brain and gut, a team of researchers reported recently in the journal PLOS Pathogens.

19 Feb 2015

New NIH grant to support development of rapid method for diagnosing mucormycosis

Speed is essential in treating deadly mucormycosis fungal infections, but a quick diagnosis is difficult because no routine blood test exists.

19 Feb 2015

NIH-sponsored clinical trials examine safety, acceptability of HIV antiretroviral medicines

Two new clinical trials are examining the safety and acceptability of antiretroviral medicines administered via injection as a means of protecting against HIV infection. The studies are being funded by the National Institute of Allergy and Infectious Diseases, part of the National Institutes of Health, and conducted by the NIAID-funded HIV Prevention Trials Network (HPTN).

19 Feb 2015

NIAID expands Tuberculosis Research Units program to drive innovation in TB research

The National Institute of Allergy and Infectious Diseases, part of the National Institutes of Health, is expanding its Tuberculosis Research Units program in an effort to drive innovation in tuberculosis (TB) research. NIAID is awarding up to $15.2 million in fiscal year 2015 and as much as $105.3 million over seven years to fund four institutions that will act as a collaborative TBRU network.

19 Feb 2015

Weill Cornell receives NIH grant to study TB-causing bacteria

In an effort to stop tuberculosis (TB) from becoming progressively less treatable worldwide, the National Institutes of Health has awarded Weill Cornell Medical College more than $6.2 million in first-year funding to support a research collaboration among six institutions in close alliance with voluntary pharmaceutical partners.

19 Feb 2015

New molecule shows promise in controlling HIV without using daily antiretroviral drugs

Scientists have created a new molecule that shows promise for controlling HIV without daily antiretroviral drugs. The molecule foils a wider range of HIV strains in the laboratory than any known broadly neutralizing HIV antibody and is more powerful than some of the most potent of these antibodies.

19 Feb 2015

New clinical trial launched in South Africa to study investigational HIV vaccine regimen

A clinical trial called HVTN 100 has been launched in South Africa to study an investigational HIV vaccine regimen for safety and the immune responses it generates in study participants. This experimental vaccine regimen is based on the one tested in the U.S. Military HIV Research Program-led RV144 clinical trial in Thailand--the first study to demonstrate that a vaccine can protect people from HIV infection.

19 Feb 2015

New facts provide baseline for future studies of epigenome's role in human development, diseases

While genomics is the study of all of the genes in a cell or organism, epigenomics is the study of all the genomic add-ons and changes that influence gene expression but aren't encoded in the DNA sequence. A variety of new epigenomic information is now available in a collection of studies published Feb. 19 in Nature by the National Institutes of Health Roadmap Epigenomics Program.

19 Feb 2015

UCSD researchers make new attempt to develop malaria vaccine candidate

Researchers at University of California, San Diego School of Medicine used algae as a mini-factory to produce a malaria parasite protein. The algae-produced protein, paired with an immune-boosting cocktail suitable for use in humans, generated antibodies in mice that nearly eliminated mosquito infection by the malaria parasite.

19 Feb 2015

TB Alliance announces initiation of first human trial of new TB drug candidate

TB Alliance has announced the start of the first human trial of a new tuberculosis (TB) drug candidate, designated TBA-354. It is the first new TB drug candidate to begin a Phase 1 clinical trial since 2009.

19 Feb 2015

NICE measures for resisting microbial drug resistance

NICE has published draft guidelines to ensure that antibiotics continue to be effective in treating infections and are not rendered useless through the development of antimicrobial resistance.

18 Feb 2015

SLU researchers halt fatty liver disease in animal model

Doctors believe that up to 30 percent of the U.S. population may have fat accumulation in the liver, known as non-alcoholic fatty liver disease (NAFLD), that can lead to a range of damaging health consequences.

18 Feb 2015

Training modules for emergency department staff to treat infectious disease patients available on CDC's website

Four Web-based training modules developed by Johns Hopkins Medicine for emergency department personnel who treat patients with infectious diseases are now available on the Centers for Disease Control and Prevention website.

18 Feb 2015

POCARED Diagnostics announces closure of another $15M in funding

POCARED Diagnostics Ltd. is an Israeli-based Diagnostics and Pre-analytical technology manufacturer with offices in the United States announced they have closed another $15 Million in funding.

17 Feb 2015

Report: Proposed SDGs may not achieve policy objectives without clearer, more measurable targets

The proposed UN Sustainable Development Goals (SDGs) - a universal set of goals to guide international development to 2030 - will struggle to achieve their stated policy objectives without clearer, more measurable targets, according to a new report released today by the International Council for Science and the International Social Science Council.

16 Feb 2015

Climate change causes emergence of more infectious diseases

The appearance of infectious diseases in new places and new hosts, such as West Nile virus and Ebola, is a predictable result of climate change, says a noted zoologist affiliated with the Harold W. Manter Laboratory of Parasitology at the University of Nebraska-Lincoln.

16 Feb 2015

Experience with Ebola outbreak highlights local responses to global health threats

Experience with the Ebola outbreak highlights local health departments' essential role in responding to global health threats posed by infectious diseases, according to a special article in the March/April issue of the Journal of Public Health Management and Practice.

16 Feb 2015

Increasing opioid doses to manage chronic pain may intensify depression

Patients who increased doses of opioid medicines to manage chronic pain were more likely to experience an increase in depression, according to Saint Louis University findings in Pain.

16 Feb 2015

Infectious Diseases News and Research

Researchers reveal how C. difficile wreaks havoc on guts, causes life-threatening diseases

HIV Prevention Trials Network launches two phase 2 studies to evaluate new HIV drugs

Natalizumab drug helps scientists confirm how 'viral reservoirs' form in HIV patients

New NIH grant to support development of rapid method for diagnosing mucormycosis

NIH-sponsored clinical trials examine safety, acceptability of HIV antiretroviral medicines

NIAID expands Tuberculosis Research Units program to drive innovation in TB research

Weill Cornell receives NIH grant to study TB-causing bacteria

New molecule shows promise in controlling HIV without using daily antiretroviral drugs

New clinical trial launched in South Africa to study investigational HIV vaccine regimen

New facts provide baseline for future studies of epigenome's role in human development, diseases

UCSD researchers make new attempt to develop malaria vaccine candidate

TB Alliance announces initiation of first human trial of new TB drug candidate

NICE measures for resisting microbial drug resistance

SLU researchers halt fatty liver disease in animal model

Training modules for emergency department staff to treat infectious disease patients available on CDC's website

POCARED Diagnostics announces closure of another $15M in funding

Report: Proposed SDGs may not achieve policy objectives without clearer, more measurable targets

Climate change causes emergence of more infectious diseases

Experience with Ebola outbreak highlights local responses to global health threats

Increasing opioid doses to manage chronic pain may intensify depression

NGS for Infectious Disease Surveillance eBook

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

Advancing Intracellular Delivery with LumiPore®

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