Bioinformatics News and Research

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Bioinformatics is the application of information techniques for the storage, retrieval, and analysis of large quantities of biological data.

AI system can help detect the degree and severity of heart transplant rejection

Heart transplantation can be a lifesaving operation for patients with end-stage heart failure. However, many patients experience organ transplant rejection, in which the immune system begins attacking the transplanted organ.

21 Mar 2022

Epigenetic changes could be a biomarker for early detection of type 1 diabetes

Children who develop type 1 diabetes show epigenetic changes in the cells of their immune system already before the antibodies of the disease are detected in their blood.

16 Mar 2022

Identification of linear B cell epitopes in the SARS-CoV-2 proteome that are conserved in humans coronaviruses

Researchers identified and validated multiple linear B-cell epitopes in the SARS-CoV-2 proteomes conserved in humans coronaviruses.

15 Mar 2022

Can wearables transform the future of healthcare?

In partnership with SLAS 2022, we spoke to Professor Michael Snyder about his latest research that investigates wearables and their future within healthcare.

From Society for Laboratory Automation and Screening (SLAS) 14 Mar 2022

Molecular signature of microorganisms in stool samples could predict pancreatic cancer risk

Pancreatic cancer is not one of the most frequently diagnosed cancers, but it is one of the most lethal due to its early local extension and metastatic behavior.

9 Mar 2022

Single protein elicits multilineage reprogramming of astrocytes in adult mouse brains

A single protein can reverse the developmental clock on adult brain cells called astrocytes, morphing them into stem-like cells that produce neurons and other cell types, UT Southwestern researchers report in a PNAS study.

9 Mar 2022

Scientists predict structure of SARS-CoV-2 frameshifting pseudoknot

Researchers recently unveiled the structure of programmed -1 ribosomal frameshifting pseudoknot of SARS-CoV-2.

8 Mar 2022

Study uncovers new clues about the cellular processes that can lead to androgen deficiency

A laboratory study at the Miller School of Medicine's Desai Sethi Urology Institute has uncovered new clues about the cellular processes that can lead to deficiencies of androgens (male hormones) such as testosterone.

4 Mar 2022

Study finds how genetic baggage can accumulate in the genomes of normal and mutant animals

You are probably familiar with the term that some people carry "a lot of extra baggage." Usually that term refers to that person's emotional history, but in genetics and our genomes, "extra baggage" can also describe the transposons lurking in our genomes, a historical record of our genomes surviving traumatic invasions during evolution.

4 Mar 2022

Biophysical fitness profile of SARS-CoV-2 Delta variant

In a recent study posted to the bioRxiv* preprint server, researchers investigated the biophysical fitness landscape of the receptor-binding domain (RBD) of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Delta variant.

1 Mar 2022

Scientists discover an innate form of immunological memory in the intestine

The innate immune system plays a crucial role in regulating host-microbe interactions, and especially in providing protection against pathogens that invade the mucosa.

28 Feb 2022

Study demonstrates that TMPRSS2, which is key to SARS-CoV-2 cell entry, is a tumor suppressor

The role played by the host enzyme TMPRSS2 in infection and cancer is the focus of a new study.

23 Feb 2022

Why is it Important to Democratize Proteomics Data?

In this interview, we speak to Steve Kosteski from IsoPlexis about the importance of single-cell proteomics within the life sciences sector.

From Society for Laboratory Automation and Screening (SLAS) 23 Feb 2022

Novel platform can become a potential approach for personalized cancer treatments

Killing cancer cells without affecting surrounding normal cells is the most desirable approach for targeted cancer therapy. However, it cannot be easily achieved due to the similarities in the properties between normal and cancer cells.

22 Feb 2022

Monitoring rise of SARS-CoV-2 variants in wastewater using genome sequencing

Researchers conduct genomic wastewater surveillance of SARS-CoV-2 following the emergence of the Alpha and Delta variants in the United Kingdom.

21 Feb 2022

SARS-CoV-2 Omicron variant prompts system sciences and precision medicine

In a new review study, researchers aimed to describe the emergence of the Omicron variant, its structure, its impact on health and health systems, and the challenges that can be expected due to this variant.

21 Feb 2022

Comparative transmission study of SARS-CoV-2 Omicron and Delta variant in England

Researchers performed an epidemiological cohort study to assess differences in transmission of the SARS-CoV-2 Omicron and Delta variants in England.

21 Feb 2022

Gradual decline in pathogenicity and enhanced cytokine induction in SARS-CoV-2 variants

A new study focuses on understanding the factors associated with the ability of the Omicron variant to infect a wide range of age groups.

20 Feb 2022

Research shows alterations in transfer RNAs at the epigenetic level in cancer

A recently published paper in the journal Molecular Cancer by the group of Dr. Manel Esteller, Director of the Josep Carreras Leukaemia Research Institute, ICREA Research Professor and Genetics Chairman at the University of Barcelona, shows that transfer RNAs for certain amino acids are altered at the epigenetic level in some types of cancer, expressing it in an exaggerated manner in some cases and being deficient in others.

17 Feb 2022

New open-source software tool could accelerate genetic discoveries

Commercially viable biofuel crops are vital to reducing greenhouse gas emissions, and a new tool developed by the Center for Advanced Bioenergy and Bioproducts Innovation should accelerate their development - as well as genetic editing advances overall.

17 Feb 2022

Bioinformatics News and Research

Further Reading

AI system can help detect the degree and severity of heart transplant rejection

Epigenetic changes could be a biomarker for early detection of type 1 diabetes

Identification of linear B cell epitopes in the SARS-CoV-2 proteome that are conserved in humans coronaviruses

Can wearables transform the future of healthcare?

Molecular signature of microorganisms in stool samples could predict pancreatic cancer risk

Single protein elicits multilineage reprogramming of astrocytes in adult mouse brains

Scientists predict structure of SARS-CoV-2 frameshifting pseudoknot

Study uncovers new clues about the cellular processes that can lead to androgen deficiency

Study finds how genetic baggage can accumulate in the genomes of normal and mutant animals

Biophysical fitness profile of SARS-CoV-2 Delta variant

Scientists discover an innate form of immunological memory in the intestine

Study demonstrates that TMPRSS2, which is key to SARS-CoV-2 cell entry, is a tumor suppressor

Why is it Important to Democratize Proteomics Data?

Novel platform can become a potential approach for personalized cancer treatments

Monitoring rise of SARS-CoV-2 variants in wastewater using genome sequencing

SARS-CoV-2 Omicron variant prompts system sciences and precision medicine

Comparative transmission study of SARS-CoV-2 Omicron and Delta variant in England

Gradual decline in pathogenicity and enhanced cytokine induction in SARS-CoV-2 variants

Research shows alterations in transfer RNAs at the epigenetic level in cancer

New open-source software tool could accelerate genetic discoveries

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