immunity News and Research

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New antibody discovery reveals powerful immune defense against tuberculosis

Researchers at the Ragon Institute have made a significant discovery about how antibodies can directly enhance the body's ability to fight Mycobacterium tuberculosis (Mtb), the bacteria responsible for tuberculosis (TB).

30 May 2025

Next-generation hydrogel supports regeneration of salivary gland-like tissue

Salivary glands play an essential role in protecting oral health by secreting saliva to aid in digestion, speech, and immunity.

30 May 2025

New insights into decades-old bladder cancer treatment offers clues for immunotherapy

More than three decades ago, the U.S. Food and Drug Administration (FDA) approved Bacillus Calmette-Guérin (BCG) as the first immunotherapy against cancer. And it is still used today to treat early-stage bladder cancer.

29 May 2025

New four drug combination sets new standard in myeloma care

A new four-drug combination is highly effective and safe in patients with newly diagnosed multiple myeloma, according to data presented at the annual meeting of the American Society of Clinical Oncology, held May 30 through June 3 in Chicago.

29 May 2025

BCG immunotherapy reprograms bone marrow to boost cancer defense

29 May 2025

Early measles vaccination gains urgency amid global outbreak

The global measles outbreak must trigger an urgent debate into whether a vaccine should be recommended earlier to better protect against the highly contagious disease during infancy, a new review states.

29 May 2025

Breakthrough study finds genes behind calcium pyrophosphate deposition disease

In a first-of-its-kind genome-wide association study (GWAS) researchers have discovered two genes, RNF144B and ENPP1, that cause calcium pyrophosphate deposition (CPPD) disease in Americans of European and African descent.

28 May 2025

Immune microRNAs drive new frontiers in cardiovascular disease research

Cardiovascular diseases (CVDs) continue to dominate global mortality statistics, with immune dysregulation emerging as a central feature in their pathogenesis.

28 May 2025

Single measles strain triggers outbreak in Milan despite high vaccination rates

A unique measles B3 lineage drove a sustained local outbreak in Milan and surrounding areas in early 2025, marking a shift from previous D8 importations. This primarily affected unvaccinated adults, raising alarms about potential endemic measles resurgence in northern Italy despite high overall vaccination coverage.

27 May 2025

Prior COVID-19 vaccination provides strong protection against emerging variants

Prior COVID-19 vaccination did not stop the immune system from mounting a protective response to the Delta and Omicron strains, though new mutation-specific antibody production dipped slightly, according to a study led by researchers at the University of Arizona Health Sciences and published in Nature Immunology.

27 May 2025

Scientists make major progress toward an effective HIV vaccine

In the long battle to create an effective HIV vaccine, scientists have made a major leap forward. A new study shows that a series of vaccines can coax the immune system to produce powerful antibodies capable of blocking a wide range of HIV strains-including those that are typically the hardest to stop.

27 May 2025

Mental health among U.S. mothers declines sharply between 2016 and 2023

A new study published in JAMA Internal Medicine reveals a concerning decline in self-reported mental health among mothers in the United States between 2016 and 2023.

27 May 2025

Targeting astrocytes could boost immunotherapy effectiveness in glioblastoma

Our study investigated the role of astrocytes, an abundant cell type in the brain, in regulating an immune response against glioblastoma (GBM)-a highly aggressive brain cancer.

23 May 2025

Study shows how daylight can boost the immune system's ability to fight infections

A breakthrough study, led by scientists at Waipapa Taumata Rau, University of Auckland, has uncovered how daylight can boost the immune system's ability to fight infections.

23 May 2025

SwRI designs bed netting systems for mosquito-based malaria control

Southwest Research Institute tapped into its drug formulation and manufacturing expertise to fabricate two bed netting prototypes targeting malaria-causing blood parasites.

21 May 2025

JAX study sheds light on infection vulnerability in patients with rare mitochondrial diseases

Patients with rare mitochondrial diseases already face a host of serious health issues, from muscle weakness to neurological problems and heart conditions.

21 May 2025

Higher maternal selenium linked to lower streptococcal infection risk in children

Higher maternal selenium levels during pregnancy were associated with a lower risk of streptococcal infections in children, suggesting a potential protective effect.

19 May 2025

What makes H5N1 a pandemic risk and how can we stop it?

A new PEARLS article in PLoS Pathogens reviews the rapid evolution and pandemic potential of emerging influenza A viruses, with a focus on H5N1. It highlights scientific advances and future strategies to outpace the virus, from next-generation vaccines to AI-driven antiviral discovery.

19 May 2025

Newly discovered Cat1 protein halts viral infections by depleting cellular fuel

Every living creature on Earth needs to protect itself from things that would do it harm. Bacteria are no different. And despite their relative simplicity, they deploy remarkably savvy defensive strategies against viral invaders.

18 May 2025

Rethinking the public health workforce for a changing world

As the U.S. continues to face complex public health challenges, a new paper published by a researcher at Columbia University Mailman School of Public Health calls for a redefinition of the public health workforce-one that goes beyond traditional boundaries and acknowledges the growing number of professionals outside government agencies who contribute to public health.

15 May 2025