Clinical Trial News and Research

RSS

Research examines link between lower-fat diet and breast cancer overall survival

Women diagnosed with breast cancer during the Women's Health Initiative Dietary Modification trial who were following a lower-fat diet had increased breast cancer overall survival, although the increase was likely partly due to better survival from several causes of death.

24 May 2018

International researchers succeed in stopping growth of mesothelioma in model animals

An international team led by researchers from the Technion-Israel Institute of Technology and NYU Langone Health have succeeded in stopping the growth of mesothelioma in model animals by inhibiting the heparanase enzyme.

24 May 2018

Antioxidant-enriched multivitamin may decrease respiratory illnesses in CF patients, finds study

Researchers at Children's Hospital Colorado and the University of Colorado School of Medicine have found that taking a specially formulated antioxidant-enriched multivitamin may decrease respiratory illnesses in people with cystic fibrosis.

24 May 2018

NIH commences first-in-human trial evaluating experimental treatment for Ebola

A first-in-human trial evaluating an experimental treatment for Ebola virus disease has begun at the National Institutes of Health (NIH) Clinical Center in Bethesda, Maryland.

24 May 2018

Study finds no link between surveillance intensity and detection of recurrence or survival in CRC patients

A national retrospective study led by researchers at The University of Texas MD Anderson Cancer Center found no association between intensity of post-treatment surveillance and detection of recurrence or overall survival in patients with stage I, II or III colorectal cancer.

23 May 2018

Investigational technology could increase donor organ supply for lung transplants

As many as 80 percent of lungs from organ donors are not used, either because they are not in good enough condition to transplant, or there are doubts about their quality and there is no way to verify their condition.

23 May 2018

PanOptica doses first patient in Phase 1/2 dose-ranging clinical trial of PAN-90806

PanOptica, Inc., a private biopharmaceutical company focused on developing innovative ophthalmology therapies, today announced that the Company has dosed the first patient in a Phase 1/2 dose-ranging clinical trial of PAN-90806, a once-daily topical eye drop formulation of a small-molecule anti-vascular endothelial growth factor (anti-VEGF) for the treatment of neovascular eye diseases.

22 May 2018

Researchers to test two-pronged approach in humans to treat advanced colorectal cancer

For the first time in humans, researchers will test a two-pronged approach to treat advanced stage colorectal cancer, potentially increasing life expectancy.

22 May 2018

Pfizer starts Phase 1/2 study of RSV vaccine candidate in healthy adult volunteers

Pfizer Inc. today announced that it has started a Phase 1/2 trial of its respiratory syncytial virus (RSV) vaccine candidate in healthy adult volunteers. RSV is a common respiratory virus that affects the lungs and airways, with significant impact on young children and older adults.

22 May 2018

Study: Medical centers more willing to perform lung transplants for severe alcoholic hepatitis patients

Increasingly, liver transplant centers are changing a long-standing practice of delaying potentially life-saving liver transplantation for patients with severe alcoholic hepatitis until after they stopped drinking alcohol for six months, according to a new study scheduled for presentation at Digestive Disease Week® (DDW) 2018.

22 May 2018

PCI along with prescribed drugs better than medication alone for treating for people with heart disease

A non-surgical procedure, called percutaneous coronary intervention, along with prescribed medication, is better than medication alone as initial treatment for people who have the most common form of heart disease, suggests an analysis of an international clinical trial co-led by St. Michael's Hospital.

22 May 2018

Eczema drug alleviates asthma symptoms and improves lung function

Two new studies of patients with difficult-to-control asthma show that the eczema drug dupilumab alleviates asthma symptoms and improves patients' ability to breathe better than standard therapies.

22 May 2018

FDA approves new drug to treat thrombocytopenia in adults with chronic liver disease

The U.S. Food and Drug Administration today approved Doptelet (avatrombopag) tablets to treat low blood platelet count (thrombocytopenia) in adults with chronic liver disease who are scheduled to undergo a medical or dental procedure. This is the first drug approved by the FDA for this use.

22 May 2018

Ethics of conducting clinical research during public health emergencies

Following the 2014-2015 Ebola outbreak in West Africa, the U.S. National Academy of Sciences, Engineering and Medicine established a committee to assess the clinical trials conducted in Guinea, Sierra Leone and Liberia.

22 May 2018

Biomarker blood test does not appear to curb antibiotic overuse, shows new study

Overall antibiotic use was not curbed by giving physicians the results of biomarker tests in patients with suspected lower respiratory tract infections, according to findings from the Procalcitonin Antibiotic Consensus Trial.

21 May 2018

CT scan still effective to determine thrombectomy treatment in stroke, study shows

A study led by a neurologist from McGovern Medical School at The University of Texas Health Science Center at Houston showed that a computed tomography could be sufficient for determining thrombectomy treatment in stroke.

21 May 2018

Researchers use MR spectroscopy to investigate mechanisms behind targeted treatment for gliomas

Using a novel imaging method, a Massachusetts General Hospital research team is investigating the mechanisms behind a potential targeted treatment for a subtype of the deadly brains tumors called gliomas.

21 May 2018

ABPI expert urges to find new 'blockbuster treatments' for brain tumors

Nearly 11,500 people are diagnosed with a brain tumor every year in the UK with fewer than 15% surviving beyond 10 years. This week’s announcement from the from the Department of Health and Social Care – following the death of Dame Tessa Jowell - that they would be doubling investment for brain cancer research to £40 million is a welcome commitment to helping achieve a goal our industry shares: finding innovative new treatments and cures for these diseases.

21 May 2018

Clinical study supports usual medical care plus chiropractic care for low back pain

U.S military personnel with low back pain who received usual medical care plus chiropractic care reported moderate improvement in their pain intensity and disability compared with patients who received usual medical care alone.

18 May 2018

Clinical trial begins enrollment to test safety of experimental MERS treatments

Enrollment has begun in an early-stage clinical trial testing the safety of two human monoclonal antibodies (mAbs) designed to treat people infected with Middle East respiratory syndrome coronavirus (MERS-CoV).

18 May 2018

Clinical Trial News and Research

Research examines link between lower-fat diet and breast cancer overall survival

International researchers succeed in stopping growth of mesothelioma in model animals

Antioxidant-enriched multivitamin may decrease respiratory illnesses in CF patients, finds study

NIH commences first-in-human trial evaluating experimental treatment for Ebola

Study finds no link between surveillance intensity and detection of recurrence or survival in CRC patients

Investigational technology could increase donor organ supply for lung transplants

PanOptica doses first patient in Phase 1/2 dose-ranging clinical trial of PAN-90806

Researchers to test two-pronged approach in humans to treat advanced colorectal cancer

Pfizer starts Phase 1/2 study of RSV vaccine candidate in healthy adult volunteers

Study: Medical centers more willing to perform lung transplants for severe alcoholic hepatitis patients

PCI along with prescribed drugs better than medication alone for treating for people with heart disease

Eczema drug alleviates asthma symptoms and improves lung function

FDA approves new drug to treat thrombocytopenia in adults with chronic liver disease

Ethics of conducting clinical research during public health emergencies

Biomarker blood test does not appear to curb antibiotic overuse, shows new study

CT scan still effective to determine thrombectomy treatment in stroke, study shows

Researchers use MR spectroscopy to investigate mechanisms behind targeted treatment for gliomas

ABPI expert urges to find new 'blockbuster treatments' for brain tumors

Clinical study supports usual medical care plus chiropractic care for low back pain

Clinical trial begins enrollment to test safety of experimental MERS treatments

eBook: Using iPSCs models for human disease research and drug discovery eBook

Latest eBooks

Industry Focus eBook - Microbiome (1st edition)

Industry Focus eBook - Cell biology (5th edition)

Advancing degrader and proximity-based drug development

Driving innovation in Korean drug development

How ELRIG Is Helping Mid-Career Scientists Navigate Leadership, Career Change and Redundancy

The role of UV-Vis in biopharma QC

Applications Engineer