Genes News and Research

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Scientists identify many new gene variants that increase risk for depression

In the largest genetic analysis of depression to date, Veterans Affairs researchers identified many new gene variants that increase the risk for depression. The groundbreaking study helps researchers better understand the biological basis of depression and could lead to better drug treatments.

28 May 2021

UC Riverside expert receives NIH grant to pursue research on moderate concussive brain injury

Viji Santhakumar, an associate professor of molecular, cell and systems biology at the University of California, Riverside, has received funding from the National Institute of Neurological Disaster and Stroke of the National Institutes of Health to further pursue research on moderate concussive brain injury, which results from car accidents or sports-related concussions.

28 May 2021

Researchers map malaria parasites in unprecedented cellular detail

Researchers have mapped in fine detail the genetic changes malaria parasites go through as they prepare to infect people.

28 May 2021

New microbial genes responsible for bile acid conversion is a major step forward for gut health

As the owner of a human body, you're carrying trillions of microbes with you everywhere you go. These microscopic organisms aren't just hitching a ride; many of them perform essential chemical reactions that regulate everything from our digestion to our immune system to our moods.

27 May 2021

Researchers use genomic sequencing technique to detect presence of various microbes

About 12,000 bacteria and viruses collected in a sampling from public transit systems and hospitals around the world from 2015 to 2017 had never before been identified, according to a study by the International MetaSUB Consortium, a global effort at tracking microbes that is led by Weill Cornell Medicine investigators.

27 May 2021

New porous biomaterial could help in bone repair

Scientists at Nanyang Technological University, Singapore (NTU Singapore) have developed a new biomaterial made entirely from discarded bullfrog skin and fish scales that could help in bone repair.

27 May 2021

Scientists develop new resources to combat cancer, advance cutting-edge genomics research

University of Virginia School of Medicine scientists have developed important new resources that will aid the battle against cancer and advance cutting-edge genomics research.

27 May 2021

Newly identified genetic variants play a role in bipolar disorder

Researchers from the Danish psychiatry research-project iPSYCH have contributed to identify 33 new genetic variants which, as it turns out, play a role in bipolar disorder.

26 May 2021

Researchers to conduct Phase 1 gene therapy trial to treat Alzheimer's disease

The National Institute on Aging (NIA), part of the National Institutes of Health, has awarded a $5 million grant to researchers at University of California San Diego School of Medicine to conduct a first-in-human Phase 1 clinical trial of a gene therapy for treating Alzheimer's disease (AD) or Mild Cognitive Impairment (MCI), a condition that often precedes full-blown dementia.

26 May 2021

Men with low testosterone levels are more susceptible to severe COVID-19

Throughout the pandemic, doctors have seen evidence that men with COVID-19 fare worse, on average, than women with the infection.

25 May 2021

Study reveals how harmless skin microbes become deadly pathogens

The bacterium Staphylococcus epidermidisis primarily a harmless microbe found on the skin and in the noses of humans.

25 May 2021

Repurposed gout medication (probenecid) shows potent inhibition of SARS-CoV-2 replication

New research by a team of scientists in the USA describes the potential utility of a drug called probenecid, commonly used to treat gout, to treat this devastating viral illness caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) – the causative virus of COVID-19.

25 May 2021

Why COVID-19 patients have more pathogenic bacteria in their noses

Researchers compared the nasal microbiome of coronavirus disease 2019 (COVID-19) patients, healthy individuals, and healthcare workers. These studies indicated an increase in the pathogen Pseudomonas aeruginosa present in the nasal microbiome of COVID-19 patients, which may be responsible for other secondary infections.

24 May 2021

Shared genetic architecture between COVID-19 severity and other health conditions

Researchers in the United States have identified a shared genetic architecture between coronavirus disease 2019 (COVID-19) severity and other health conditions.

24 May 2021

The potential therapeutic value of CDK6 inhibitors in critical COVID-19

While drug repurposing has been explored in the context of the current coronavirus disease 2019 (COVID-19) pandemic, the success of this strategy has been limited so far. A new study, released as a preprint on the medRxiv* server, describes a new method of identifying a promising hit among drugs already in use.

24 May 2021

New immunotherapy shows promising results in subgroup of people with type 1 diabetes

A clinical study led by Linköping University and financed by pharmaceuticals company Diamyd Medical has investigated whether immunotherapy against type 1 diabetes can preserve the body's own production of insulin.

24 May 2021

Researchers are developing first prognostic, therapeutic epigenetic biomarker for pancreatic cancer patients

By 2030, pancreatic ductal adenocarcinoma (PDAC), the most lethal form of pancreatic cancer, is projected to become the second leading cause of cancer-related deaths in the United States.

24 May 2021

Genetically engineered intestinal organoids reveal potential treatment targets against SARS-CoV-2

Using CRISPR/Cas9 and human intestinal organoids to study genes implicated in the biology of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), researchers from the Netherlands identified a specific serine protease (TMPRSS2) as an attractive pan-coronavirus therapeutic target. Their exciting findings are available in a study currently available on the bioRxiv* preprint server.

24 May 2021

STING agonist diABZI shows promise against SARS-CoV-2 variants

COVID-19 vaccines are the most effective way to prevent severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. For people who are already infected, new research suggests the small molecule stimulator of interferon genes (STING) agonist-1, diABZI, may be effective in controlling SARS-CoV-2 infection — including those caused by variants.

23 May 2021

University of Freiburg professor honored for groundbreaking results on the brain’s immune system

The blood-brain barrier is an impenetrable barrier between the circulating blood and the brain established before birth that prevents immune cells from entering the brain from the body's immune system. Thus, the brain has its own immune system with a key actor called microglia.

21 May 2021

Genes News and Research

Scientists identify many new gene variants that increase risk for depression

UC Riverside expert receives NIH grant to pursue research on moderate concussive brain injury

Researchers map malaria parasites in unprecedented cellular detail

New microbial genes responsible for bile acid conversion is a major step forward for gut health

Researchers use genomic sequencing technique to detect presence of various microbes

New porous biomaterial could help in bone repair

Scientists develop new resources to combat cancer, advance cutting-edge genomics research

Newly identified genetic variants play a role in bipolar disorder

Researchers to conduct Phase 1 gene therapy trial to treat Alzheimer's disease

Men with low testosterone levels are more susceptible to severe COVID-19

Study reveals how harmless skin microbes become deadly pathogens

Repurposed gout medication (probenecid) shows potent inhibition of SARS-CoV-2 replication

Why COVID-19 patients have more pathogenic bacteria in their noses

Shared genetic architecture between COVID-19 severity and other health conditions

The potential therapeutic value of CDK6 inhibitors in critical COVID-19

New immunotherapy shows promising results in subgroup of people with type 1 diabetes

Researchers are developing first prognostic, therapeutic epigenetic biomarker for pancreatic cancer patients

Genetically engineered intestinal organoids reveal potential treatment targets against SARS-CoV-2

STING agonist diABZI shows promise against SARS-CoV-2 variants

University of Freiburg professor honored for groundbreaking results on the brain’s immune system

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