Infectious Diseases News and Research

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Janssen granted Priority Review from FDA for YONDELIS (trabectedin) NDA to treat STS patients

Janssen Research & Development, LLC announced today that the U.S. Food and Drug Administration has granted Priority Review for the New Drug Application (NDA) for YONDELIS (trabectedin) to treat patients with advanced soft tissue sarcoma (STS), including liposarcoma and leiomyosarcoma subtypes, who have received prior chemotherapy including an anthracycline.

3 Feb 2015

Large clinical trial to assess safety, efficacy of two experimental Ebola vaccines opens in Liberia

A large clinical trial to assess the safety and efficacy of two experimental vaccines to prevent Ebola virus infection is now open to volunteers in Liberia. The trial is being led by a recently formed Liberia-U.S. clinical research partnership and is sponsored by the National Institute of Allergy and Infectious Diseases, part of the National Institutes of Health.

3 Feb 2015

ABIVAX doses first HIV positive patient in ABX464 Phase IIa clinical trial

ABIVAX, a leading clinical stage biotech company developing and commercialising anti-viral compounds and human vaccines, today announced that enrolment has been initiated and the first HIV positive patient dosed in a Phase IIa clinical trial of ABX464.

2 Feb 2015

Scientists identify how 'mini-brain' in spinal cord helps keep our body balanced

Walking across an icy parking lot in winter--and remaining upright--takes intense concentration. But a new discovery suggests that much of the balancing act that our bodies perform when faced with such a task happens unconsciously, thanks to a cluster of neurons in our spinal cord that function as a "mini-brain" to integrate sensory information and make the necessary adjustments to our muscles so that we don't slip and fall.

2 Feb 2015

Study: About one-third of teens, young adults face social barriers to diabetes management

Managing type 1 diabetes is a never-ending task that requires multiple blood glucose tests, carbohydrate calculations and insulin injections or infusions. This constant effort to control the disease is daunting at any age - and it's especially challenging for teens and young adults.

2 Feb 2015

Drug-resistant HIV viruses can spread rapidly, shows study

Drug-resistant HIV viruses can spread rapidly. This is the conclusion of a study conducted as part of the SWISS HIV Cohort Study, which is supported by the SNSF. Only the continuous introduction of new drugs can stop the virus from getting the upper hand.

2 Feb 2015

Immunization can prevent measles

The recent measles outbreak linked to Disney amusement parks in southern California should not be a concern for anyone who has had measles in the past or who has received two doses of the measles vaccine.

2 Feb 2015

VG Life Sciences issues patent relating to treatment of IBD through CLIP-inducing agent

VG Life Sciences, (VGLS), a biotechnology company developing therapies for autoimmune and infectious diseases, today announced the U.S. Patent and Trademark Office (USPTO) has issued U.S. Patent No. 8906846, covering a method of treating inflammatory bowel disease (IBD) through the administration of a CLIP-inducing agent.

31 Jan 2015

Rare respiratory virus could be linked to severe neurological illness in children

A cluster of children from Colorado in the USA have been treated for muscle weakness or paralysis that may be connected to a nationwide outbreak of a usually rare respiratory virus called enterovirus D68 (EV-D68), one of more than 100 non-polio enteroviruses.

31 Jan 2015

Researchers identify molecular pathways that could lead to new therapeutic targets for cerebral malaria

A drug already approved for treating other diseases may be useful as a treatment for cerebral malaria, according to researchers at Harvard T. H. Chan School of Public Health. They discovered a novel link between food intake during the early stages of infection and the outcome of the disease, identifying two molecular pathways that could serve as new targets for treatment.

30 Jan 2015

Synthetic compound shows antibiotic action against MRSA

Microbiologists and chemists at the University of South Florida have developed and patented a synthetic compound that has shown antibiotic action against methicillin resistant Staphylococcus aureus, also known as MRSA, which can cause many serious infections and deaths.

30 Jan 2015

UAB doctor says measles can be halted with safe, effective measles vaccine

An ongoing, multistate measles outbreak linked to a California amusement park has already caused 68 confirmed cases between Jan. 1 and 23, according to the Centers for Disease Control and Prevention.

30 Jan 2015

Immunomic Therapeutics, Astellas Pharma sign license deal to develop LAMP-vax DNA vaccines

Immunomic Therapeutics, Inc. ("Immunomic Therapeutics"), a company developing next-generation vaccines based on the LAMP-vax platform, and Astellas Pharma Inc. ("Astellas") today announced they have entered into an exclusive license agreement for Japan to develop and commercialize JRC2-LAMP-vax, Immunomic Therapeutics' vaccine designed to treat allergies induced by Japanese red cedar pollen.

30 Jan 2015

Adropin hormone offers a promising treatment option for type 2 diabetes

In a study published in Molecular Metabolism, a SLU researcher has found that adropin, a hormone that regulates whether the body burns fat or sugar during feeding and fasting cycles, can improve insulin action in obese, diabetic mice, suggesting that it may work as a therapy for type 2 diabetes.

30 Jan 2015

Researchers receive $2.2M grant to study links between depression and cardiovascular disease in HIV patients

Jesse Stewart, Ph.D., associate professor of psychology in the School of Science at Indiana University-Purdue University Indianapolis, and two colleagues have received a $2.2 million National Institutes of Health grant to investigate the links between depression, depression treatment and cardiovascular disease in adults with HIV.

29 Jan 2015

Quest Diagnostics, CDC partner to identify trends in diagnosis and treatment for viral hepatitis

Quest Diagnostics, the world’s leading provider of diagnostic information services, today announced that it will collaborate with the Centers for Disease Control and Prevention to identify trends in screening, diagnosis and treatment for four strains of viral hepatitis in the United States, based on insights revealed by analysis of Quest’s national testing database.

From Quest Diagnostics 29 Jan 2015

Quest Diagnostics, CDC collaborate to reduce deaths from hepatitis

Quest Diagnostics, the world's leading provider of diagnostic information services, today announced that it will collaborate with the Centers for Disease Control and Prevention to identify trends in screening, diagnosis and treatment for four strains of viral hepatitis in the United States, based on insights revealed by analysis of Quest's national testing database.

From Quest Diagnostics 28 Jan 2015

TGH develops unique new method to help high-risk patients receive a lung transplant

A unique new method to treat a specific group of patients who are at greater risk of rejecting a donor lung, allowing them to live longer after transplant without rejection, has been developed by the Toronto Lung Transplant Program at Toronto General Hospital, University Health Network.

28 Jan 2015

Pollinator decline could increase risk of malnutrition, disease

A new study shows that more than half the people in some developing countries could become newly at risk for malnutrition if crop-pollinating animals -- like bees -- continue to decline.

28 Jan 2015

Antibiotic use by travellers may promote spread of drug-resistant 'super-bacteria'

Treating travellers' diarrhoea with antibiotics can promote the spread of drug-resistant "super-bacteria".

28 Jan 2015

Infectious Diseases News and Research

Janssen granted Priority Review from FDA for YONDELIS (trabectedin) NDA to treat STS patients

Large clinical trial to assess safety, efficacy of two experimental Ebola vaccines opens in Liberia

ABIVAX doses first HIV positive patient in ABX464 Phase IIa clinical trial

Scientists identify how 'mini-brain' in spinal cord helps keep our body balanced

Study: About one-third of teens, young adults face social barriers to diabetes management

Drug-resistant HIV viruses can spread rapidly, shows study

Immunization can prevent measles

VG Life Sciences issues patent relating to treatment of IBD through CLIP-inducing agent

Rare respiratory virus could be linked to severe neurological illness in children

Researchers identify molecular pathways that could lead to new therapeutic targets for cerebral malaria

Synthetic compound shows antibiotic action against MRSA

UAB doctor says measles can be halted with safe, effective measles vaccine

Immunomic Therapeutics, Astellas Pharma sign license deal to develop LAMP-vax DNA vaccines

Adropin hormone offers a promising treatment option for type 2 diabetes

Researchers receive $2.2M grant to study links between depression and cardiovascular disease in HIV patients

Quest Diagnostics, CDC partner to identify trends in diagnosis and treatment for viral hepatitis

Quest Diagnostics, CDC collaborate to reduce deaths from hepatitis

TGH develops unique new method to help high-risk patients receive a lung transplant

Pollinator decline could increase risk of malnutrition, disease

Antibiotic use by travellers may promote spread of drug-resistant 'super-bacteria'

NGS for Infectious Disease Surveillance eBook

Evaluating new approaches for rare disease genomics

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Advancing Intracellular Delivery with LumiPore®

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