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DNA of uncultured organisms sequenced using novel single cell genome sequencing approach

Scientists from the U.S. Department of Energy (DOE) Joint Genome Institute (JGI) and the Bigelow Laboratory for Ocean Sciences have assembled high quality, contamination-free draft genomes of uncultured biodegrading microorganisms using a novel single cell genome sequencing approach.

22 Apr 2009

Study finds link between a mother's height and the health of her children

Researchers at the Harvard School of Public Health (HSPH) have found a link between a mother's height and the health of her children in a study using national data from India.

22 Apr 2009

Peregrine's PS-targeting antibodies highlighted in AACR Annual Meeting studies

Peregrine Pharmaceuticals, Inc. has reported that two preclinical studies presented during the AACR 100th Annual Meeting 2009 provided further confirmation of the immunomodulatory mechanisms contributing to the anti-tumor activity of its phosphatidylserine (PS) targeting antibodies.

22 Apr 2009

The DNA proteome

The human genome complete sequencing project in 2003 revealed the enormous instruction manual necessary to define a human being.

22 Apr 2009

Potential genetic cause of congenital defect colonic atresia

In a finding that helps resolve a long-standing question in developmental biology, Klaus H. Kaestner, PhD, Professor of Genetics, and colleagues report in the journal Developmental Cell this week about how the mammalian gut forms. Mice were genetically engineered to lack the protein Cdx2 in the cells that normally go on to form the stomach and intestine.

22 Apr 2009

New clues to how stem cells form

An Emory University study shows some of the first direct evidence of a process required for epigenetic reprogramming between generations – a finding that could shed more light on the mechanisms of fertilization, stem-cell formation and cloning.

16 Apr 2009

Next generation ultra-thin materials only one molecule thick

With the human genome in hand, biochemists have cataloged the 3-D structures of thousands of proteins isolated from living cells.

14 Apr 2009

Safety of Bitter orange herbal weight loss product questioned

The Australian Therapeutic Goods Administration (TGA) is reportedly examining whether there are any risks associated with an over-the-counter (OTC) herbal weight loss programme sold in Australia.

13 Apr 2009

microRNAs manipulate cells to one day create safe embryonic-like stem cells

A team of UCSF researchers has for the first time used tiny molecules called microRNAs to help turn adult mouse cells back to their embryonic state.

12 Apr 2009

Funding boost for Bristol research on titanium bone implants

Dr Jason Mansell, Lecturer in Bone Biology, has been awarded £57,000 from the International Team for Implantology (Switzerland) for work on titanium bone implants.

12 Apr 2009

Kidney reconstruction performed though single incision hidden in the navel

With a single incision hidden in the navel, surgeons at the University of California, San Diego Medical Center have successfully removed a cancerous kidney tumor while saving the patient's kidney.

9 Apr 2009

Does exercise help prevent breast cancer?

A new federally funded University of Pennsylvania School of Medicine study aims to learn whether women at high risk of breast cancer can use exercise to meaningfully reduce their risk of getting the disease.

6 Apr 2009

Monoclonal antibody cancer therapy

The strategy of using monoclonal antibodies for cancer treatment was first described in the late 1970s with the promise that they could be developed into therapies that were highly specific to cancer cells, killing them with few or no side effects.

6 Apr 2009

New 90-second radiotherapy therapy called RapidArc

The University of Alabama at Birmingham (UAB) this month became the first U.S. medical center to offer a speedier cancer radiation therapy.

5 Apr 2009

Eli Lilly announces inconclusive study results for mGlu2/3 in acute schizophrenia

Eli Lilly and Company has announced inconclusive Phase II clinical trial results from Study HBBI investigating LY2140023 monohydrate, also known as mGlu2/3, for the treatment of patients suffering from acute schizophrenia.

29 Mar 2009

Positive phase 3 uveitis trial results for voclosporin

Isotechnika Inc. has announced that their partner, Lux Biosciences, Inc., reported the results from the three Phase 3 LUMINATE trials investigating voclosporin oral capsule (LUVENIQ or LX211) for the treatment of uveitis.

29 Mar 2009

Radius starts Ppase 2a trial of RAD1901 in menopausal hot flashes

Radius Health ("Radius") announced today that the first patient has been dosed in the company's proof-of-concept Phase 2a study of RAD1901, an investigational selective estrogen receptor modulator (SERM) undergoing clinical evaluation for treatment of vasomotor symptoms (menopausal hot flashes).

24 Mar 2009

Scientists make a new protein from scratch

No doubt proteins are complex. Most are "large" and full of interdependent branches, pockets and bends in their final folded structure.

23 Mar 2009

Heart bypass surgery better than angioplasty for certain patients

After three years working with investigators from 10 different clinical trials around the world from Brazil to London to Pittsburgh, Stanford University School of Medicine researchers have pooled enough individual patient data to compare the effectiveness of coronary artery bypass surgery with the less-invasive angioplasty procedure on specific groups of patients for the first time.

20 Mar 2009

Obama advisers suggest President might not oppose taxing some employer-sponsored health benefits

The Obama administration is "signaling to Congress" that President Obama "could support taxing some employee health benefits" to help offset the cost of health care reform, a move supported by "several influential lawmakers and many economists" but "opposed by union leaders and some businesses," the New York Times reports (Calmes/Pear, New York Times, 3/15).

16 Mar 2009