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New study identifies inherited genetic variants that raise risk of clonal hematopoiesis

A new study led by researchers at Harvard Medical School and the Harvard T.H. Chan School of Public Health has identified some of the first known inherited genetic variants that significantly raise a person's likelihood of developing clonal hematopoiesis, an age-related white blood cell condition linked with higher risk of certain blood cancers and cardiovascular disease.

12 Jul 2018

Fighting cancer with engineered cancer cells

Researchers at Brigham and Women's Hospital have engineered cancer cells that track and kill cancer cells. The modified cancer cells have demonstrated anti-cancer efficacy in preclinical studies, destroying both primary and metastatic tumours.

12 Jul 2018

Attempts to reunite separated families should not misuse medical tests, says ACP

In a new policy issued today, the American College of Physicians (ACP) stated that immigrant families who have been separated at the border should be reunited as expeditiously as possible.

12 Jul 2018

New findings refine link between clonal hematopoiesis and blood cancer risk

It's a common occurrence in elderly people: Blood cells carrying mutated DNA explosively increase in number, resulting in genetic "mosaicism": the presence of a population of cells that carries an altered genome.

12 Jul 2018

Novel informatics tool helps predict genomic features associated with specific drug responses

The rise of genomics, the shift from considering genes singly to collectively, is adding a new dimension to medical care; biomedical researchers hope to use the information contained in human genomes to make better predictions about individual health, including responses to therapeutic drugs.

12 Jul 2018

Researchers discover why CRISPR gene editing sometimes fails

A study has explained for the first time why the CRISPR gene editing tool fails to work in 15% cases, and has suggested methods to prevent this.

11 Jul 2018

Researchers reveal why CRISPR gene editing sometimes fails to work

Researchers from the University of Illinois at Chicago are the first to describe why CRISPR gene editing sometimes fails to work, and how the process can be made to be much more efficient.

11 Jul 2018

Researchers find ATM protein that can trigger production of antioxidants

One reason we're supposed to eat a variety of colorful fruits and vegetables is because they contain nutritious compounds called antioxidants.

11 Jul 2018

Researchers develop 3D map of gene interactions that play key role in heart disease

Researchers have developed a 3D map of the gene interactions that play a key role in cardiovascular disease, a study in eLife reports.

11 Jul 2018

Researchers develop new method to identify genes contributing to heritable cancer risk

Researchers at the Centre for Genomic Regulation in Barcelona developed a new method to systematically identify genes contributing to heritable cancer risk.

10 Jul 2018

Researchers use genome editing to reduce cholesterol levels in animal model

Using genome editing to inactivate a protein called PCSK9 effectively reduces cholesterol levels in rhesus macaques, a species of monkey, according to researchers from the Perelman School of Medicine at the University of Pennsylvania.

10 Jul 2018

Scientists sequence and analyze genomes of Candida albicans

Candida albicans is one of the most formidable fungal species, causing infection in humans. Investigating the structure and reproduction methods of pathogenic populations can help us to understand how they emerge and spread.

10 Jul 2018

New study reveals transmission of NDM-bacteria between dogs and humans

In 2015, a New Delhi -metallo-beta-lactamase Escherichia coli bacteria was discovered in two Finnish dogs.An article recently published in the journal Eurosurveillance reveals that the dogs' owner did also carry the bacterium.

9 Jul 2018

Researchers unmask functioning of protein involved in DNA repair during spermatogenesis

Researchers from the Department of Cell Biology, Physiology and Immunology and the Institute for Biotechnology and Biomedicine of the Universitat Autònoma de Barcelona have unmasked the functioning of a protein involved in DNA repair, ATR, in the meiotic recombination process which takes place during the development of spermatocytes - sperm precursor cells- and how inhibiting this protein causes anomalies which block spermatogenesis.

9 Jul 2018

Study finds key evidence about genetic make-up of heart condition linked to sudden arrhythmic death

A new study published in Circulation, a peer-reviewed journal of the American Heart Association and led by a cardiologist at the Peter Munk Cardiac Centre at Toronto General Hospital has found evidence that only one of the 21 genes normally associated with Brugada Syndrome, a serious genetic heart condition associated with the risk of sudden arrhythmic death, is a definitive cause of the condition.

9 Jul 2018

Widespread transfer of genes between species appears to be key driver of evolution

Far from just being the product of our parents, University of Adelaide scientists have shown that widespread transfer of genes between species has radically changed the genomes of today's mammals, and been an important driver of evolution.

9 Jul 2018

Researchers discover critical link in mapping recurrent mutations of melanoma

A critical link in mapping recurrent mutations of melanoma -- the most serious form of skin cancer in humans -- has been discovered by researchers at Washington State University School of Molecular Biosciences, in collaboration with researchers at Georgia State University.

6 Jul 2018

Researchers find new way to convert skin cells into pluripotent stem cells

Our bodies consist of many different kinds of cells, each with their own role. The Japanese scientist Shinya Yamanaka had made earlier the discovery, earning the Nobel Prize in 2012, that cells from adult skin can be converted to cells typical of early embryos, so-called induced pluripotent stem cells.

6 Jul 2018

The Bioethics of AI in the Healthcare Industry

With the advent of artificial intelligence, it is imperative that we examine the ethics of machine learning and data collection. Hugh Whittall, Director of the Nuffield Council on Bioethics, explains what AI is, how it is transforming the healthcare industry and the ethical concerns of the Council.

6 Jul 2018

Researchers develop switch that can control genome editing

Researchers have developed a biological switch that reliably triggers protein expression and enables the control of genome editing tools.

3 Jul 2018

Genome News and Research

New study identifies inherited genetic variants that raise risk of clonal hematopoiesis

Fighting cancer with engineered cancer cells

Attempts to reunite separated families should not misuse medical tests, says ACP

New findings refine link between clonal hematopoiesis and blood cancer risk

Novel informatics tool helps predict genomic features associated with specific drug responses

Researchers discover why CRISPR gene editing sometimes fails

Researchers reveal why CRISPR gene editing sometimes fails to work

Researchers find ATM protein that can trigger production of antioxidants

Researchers develop 3D map of gene interactions that play key role in heart disease

Researchers develop new method to identify genes contributing to heritable cancer risk

Researchers use genome editing to reduce cholesterol levels in animal model

Scientists sequence and analyze genomes of Candida albicans

New study reveals transmission of NDM-bacteria between dogs and humans

Researchers unmask functioning of protein involved in DNA repair during spermatogenesis

Study finds key evidence about genetic make-up of heart condition linked to sudden arrhythmic death

Widespread transfer of genes between species appears to be key driver of evolution

Researchers discover critical link in mapping recurrent mutations of melanoma

Researchers find new way to convert skin cells into pluripotent stem cells

The Bioethics of AI in the Healthcare Industry

Researchers develop switch that can control genome editing

The art of CRISPR: The power and promise of gene editing eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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