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New mouse model grants insight into the genetic and molecular mechanisms underpinning acute myeloid leukemia

Leukaemia - cancer of blood or bone marrow is caused by mutations that allow defective blood cells to accumulate and displace healthy blood.

8 Apr 2008

Leaky blood vessels open up nerve cells to toxic assault In Lou Gehrig's disease

Leaky blood vessels that lose their ability to protect the spinal cord from toxins may play a role in the development of amyotrophic lateral sclerosis, better known as ALS or Lou Gehrig's disease, according to research published in the April issue of Nature Neuroscience.

7 Apr 2008

T-cadherin affects blood vessel growth in breast cancer, hormone from fat cells may play a role

Researchers at the Burnham Institute for Medical Research (Burnham) may have found a new option for targeted breast cancer therapy by showing the link between a certain protein and the formation and development of blood vessels that feed breast tumors.

7 Apr 2008

Mitochondria play role in pathogenesis of AD and estrogen-induced neuroprotection

As the major source of free radicals in cells, mitochondria contribute to the high levels of oxidative stress believed to play a role in the pathogenesis of Alzheimer's disease.

7 Apr 2008

Rare genetic syndrome may hold key to cure for heat stroke

A genetic disorder that can cause a fatal rise in body temperature in some patients undergoing general anesthesia may hold the key to a cure for heat stroke, according to research published in the April 4 edition of the journal Cell.

4 Apr 2008

Human breast tumors' 'microenvironment' primes them for metastasis

The environment within primary breast tumors can "empower" cells that break free and enter the bloodstream to successfully invade other organs, researchers report in the April 4th Cell, a publication of Cell Press.

4 Apr 2008

Healthcare providers who discuss intimate piercings earn patients' trust

On April 2, 2008, UC San Diego Medical Center-Hillcrest celebrated the opening of an expanded Neonatal Intensive Care Unit (NICU) designed for the 24-hour specialized care of premature infants and newborns with complications.

4 Apr 2008

Tai Chi improves control of type 2 diabetes

Tai Chi exercises can improve the control of type 2 diabetes, suggests a small study, published ahead of print in the British Journal of Sports Medicine.

1 Apr 2008

New breakthrough discovery on TB

Medical scientists from the University of Leicester, together with colleagues from St Georges, University of London, funded principally by the Medical Research Council (MRC) and The Wellcome Trust, have published details of a new breakthrough discovery on TB.

1 Apr 2008

Fat kids better off doing less intensive exercise if they are to shed the pounds effectively

The researchers assessed the rate at which fat was burned (fat oxidation) during graded leg cycling exercises in thirty 12 year old boys, 17 of whom were obese. The others were lean and healthy.

1 Apr 2008

Fasting could offer protection from chemotherapy effects

A new study is suggesting that short-term fasting could help protect cancer patients against the effects of chemotherapy.

1 Apr 2008

International team of scientists discover clue to delay of life on Earth

Scientists from around the world have reconstructed changes in Earth's ancient ocean chemistry during a broad sweep of geological time, from about 2.5 to 0.5 billion years ago.

28 Mar 2008

Red wine antioxidant resveratrol kills cancer

Rochester researchers showed for the first time that a natural antioxidant found in grape skins and red wine can help destroy pancreatic cancer cells by reaching to the cell's core energy source, or mitochondria, and crippling its function.

26 Mar 2008

EpiCept announces opinion by European Regulatory Authority on Ceplene

EpiCept Corporation has announced that the European Committee for Medicinal Products for Human Use (CHMP), the scientific committee of the European Medicines Agency (EMEA), has issued, as expected following the trend vote announced last month, a negative opinion regarding the marketing authorization application (MAA) for Ceplene (histamine dihydrochloride) for the remission maintenance and prevention of relapse of patients with Acute Myeloid Leukemia (AML) in first remission.

24 Mar 2008

Parental observations and perceptions important in detecting sleep problems in children

A new study from the University of Rochester has found that parental observations and perceptions of their childrens' sleep habits are a valuable supplement to objective laboratory tests in detecting obstructive sleep apnea (OSA).

20 Mar 2008

First detailed look at the molecular pathways underlying sleep apnea

Researchers at the University of Pennsylvania School of Medicine have provided, for the first time, a detailed look at the molecular pathways underlying sleep apnea, which affects more than twelve million Americans, according to the National Institutes of Health.

20 Mar 2008