Immune System News and Research

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Scientific breakthrough provides insights into basic mechanisms of allergic reactions

An international research team has been able to describe the overall structure of the antibody type IgE, which is the key molecule in allergic diseases.

24 Feb 2020

Inflammation caused by radiation can promote survival of triple-negative breast cancer cells

While radiation is successfully used to treat breast cancer by killing cancer cells, inflammation caused as a side-effect of radiation can have a contrary effect by promoting the survival of triple-negative breast cancer cells, according to research published online in the International Journal of Radiation Biology by Jennifer Sims-Mourtada, Ph.D., director of Translational Breast Cancer Research at ChristianaCare's Helen F. Graham Cancer Center & Research Institute.

24 Feb 2020

UCI makes tremendous strides in prevention, early detection and treatment of cancer

Like most people, John Gifford wasn't looking forward to a colonoscopy when he arrived on the UCI Medical Center campus in Orange in 2018.

23 Feb 2020

UCI neuro-oncologist uses comprehensive approach to battle brain cancer

When you're facing a cancer diagnosis with an average survival span of 12 to 18 months, every milestone is a victory.

23 Feb 2020

Using newly discovered immune cell type to fight pancreatic cancer

Immunotherapy is showing great promise for treating cancer. But so far, this approach has been effective in only about 20% of all cancers. To advance those results, researchers are looking for new ways to mobilize the immune system to destroy tumors.

23 Feb 2020

Comprehensive tumor profiling reveals why osteosarcoma does not respond to immunotherapy

Comprehensive profiling of tumor samples taken from patients with osteosarcoma shows that multiple factors contribute to the traditionally poor responses observed from treatment with immune checkpoint inhibitors, according to new research from The University of Texas MD Anderson Cancer Center.

22 Feb 2020

A step towards precision medicine for the management of monogenic diabetes

Diabetes affects more than 400 million people worldwide and is a major public health problem. Although commonly referred to as a single disease, it actually constitutes a group of metabolic disorders with hyperglycemia as a common feature. Of all its forms, monogenic diabetes - due to a mutation in one of the genes involved in the management of blood sugar levels - affects 1% to 4% of all cases of diabetes.

22 Feb 2020

Isolating Single T-cells of Interest using an Optofluidic Platform

Researchers are in desperate need of single-cell analysis techniques and those that allow the isolation of high-value T-cells for research and development.

From Bruker Cellular Analysis 21 Feb 2020

Administering immunotherapy alongside chemoradiation for advanced NSCLC appears to be safe and tolerable

Research from Rutgers Cancer Institute of New Jersey shows administering the immunotherapy drug pembrolizumab together with chemotherapy given at the same time as radiation treatment (chemoradiation) is safe and tolerable as a first-line therapy for patients with stage 3 non-small cell lung cancer.

21 Feb 2020

Scientists make important discovery with implications for people living with AMD

Scientists from Trinity College Dublin have made an important discovery with implications for those living with a common, debilitating eye disease (age-related macular degeneration, AMD) that can cause blindness.

20 Feb 2020

Researchers identify a protein that aids in colorectal cancer metastasis

A protein that helps colorectal cancer cells spread to other parts of the body could be an effective treatment target.

20 Feb 2020

Cancer risk in psoriatic patients

A new study published in February 2020 in the journal JAMA Dermatology reports that there is a 21% increased risk of cancer in patients with psoriasis, but not with psoriatic arthritis alone.

19 Feb 2020

Exploring how brain inflammation after stroke can be shaped to support recovery

University of Kentucky College of Medicine researcher Ann Stowe describes her career path as nontraditional. After earning a bachelor's degree in fine arts, Stowe decided to pursue graduate study in biomedical research instead of art history.

19 Feb 2020

Vaccine for COVID-19 coronavirus could soon be a reality

A team of researchers from the University of Texas at Austin and the National Institutes of Health have managed to make significant progress in the development of a vaccine against the fast-spreading and virulent COVID-19/Novel coronavirus that started in Wuhan, Hubei province of China in December 2019 and is still infecting thousands.

19 Feb 2020

How malaria evades the body’s immune response

Malaria is a life-threatening disease caused by parasites that are transmitted to people through the bites of infected female Anopheles mosquitoes. In 2018, there were over 200 million cases of malaria worldwide. Now, a team of researchers found evidence that the malaria parasite can detect a molecule released by approaching immune cells, using it to protect itself and evade the attack by the body’s immune system.

19 Feb 2020

Drugs targeting T cells may be effective in treating cerebral malaria

Researchers at the National Institutes of Health found evidence that specific immune cells may play a key role in the devastating effects of cerebral malaria, a severe form of malaria that mainly affects young children.

18 Feb 2020

Researchers uncover genetic mechanisms that govern brain plasticity

Genetic mechanisms that govern brain plasticity - the brain's ability to change and adapt - have been uncovered by researchers at the University of Birmingham.

18 Feb 2020

Fruit flies have a new defense strategy to deal with oxidative stress

Oxidative stress affects all living organisms, and the damage it causes is believed to play a part in cancer, diabetes, Alzheimer's disease and a number of other health conditions.

18 Feb 2020

Plasma from recovered patients used to treat coronavirus a valid approach, WHO says

The COVID-19 (coronavirus disease) outbreak has taken nearly 1,900 people and infected more than 73,000 people, mainly in China. It has spread to 28 countries, prompting scientists to develop potential therapies to treat deadly viral infections. Now, Chinese doctors are using plasma therapy to treat coronavirus patients.

18 Feb 2020

UT Southwestern scientists discover potential vulnerabilities in new coronavirus

UT Southwestern Medical Center data scientists analyzing genetic sequences of the COVID-19 coronavirus have identified potential vulnerabilities that could help in vaccine development and further study of the infectious disease now spreading worldwide.

17 Feb 2020

Immune System News and Research

Scientific breakthrough provides insights into basic mechanisms of allergic reactions

Inflammation caused by radiation can promote survival of triple-negative breast cancer cells

UCI makes tremendous strides in prevention, early detection and treatment of cancer

UCI neuro-oncologist uses comprehensive approach to battle brain cancer

Using newly discovered immune cell type to fight pancreatic cancer

Comprehensive tumor profiling reveals why osteosarcoma does not respond to immunotherapy

A step towards precision medicine for the management of monogenic diabetes

Isolating Single T-cells of Interest using an Optofluidic Platform

Administering immunotherapy alongside chemoradiation for advanced NSCLC appears to be safe and tolerable

Scientists make important discovery with implications for people living with AMD

Researchers identify a protein that aids in colorectal cancer metastasis

Cancer risk in psoriatic patients

Exploring how brain inflammation after stroke can be shaped to support recovery

Vaccine for COVID-19 coronavirus could soon be a reality

How malaria evades the body’s immune response

Drugs targeting T cells may be effective in treating cerebral malaria

Researchers uncover genetic mechanisms that govern brain plasticity

Fruit flies have a new defense strategy to deal with oxidative stress

Plasma from recovered patients used to treat coronavirus a valid approach, WHO says

UT Southwestern scientists discover potential vulnerabilities in new coronavirus

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