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British Heart Foundation funded Surrey project will address cardiac safety in novel anti-malarial agents

Understanding how drugs used to treat malaria impact the human heart is essential to finally toppling one of the world's most common but serious infections, according to researchers at the University of Surrey.

10 Aug 2022

Rice University researchers model a key mechanism by which DNA replicates

Knowing the structure of a complex biological system isn't nearly enough to understand how it works. It helps to know how the system moves.

10 Aug 2022

A broad sarbecovirus-neutralizing antibody cocktail

Researchers present a rational approach for identifying SARS-CoV-2 receptor-binding domain-targeted broad neutralizing antibody cocktails.

9 Aug 2022

Neuronal cilia are important for dopamine receptor 1 signaling, study shows

A historically overlooked rod-like projection present on nearly every cell type in the human body may finally be getting its scientific due: A new study has found that these appendages, called cilia, on neurons in the brain have a key role in ensuring a specific dopamine receptor's signals are properly received.

9 Aug 2022

Using microrobotic platforms for endodontic therapy and diagnostics

With its irregularities and anatomical complexities, the root canal system is one of the most clinically challenging spaces in the oral cavity.

9 Aug 2022

Dual therapy offers both benefit and risk after common type of cardiac surgery

A new analysis shows that a combination of two anti-platelets drugs can benefit patients after the most common type of cardiac surgery - while also increasing the risk of potentially dangerous bleeding.

9 Aug 2022

Scripps, UCLA chemists develop a 'molecular editing' toolkit for modifying bicyclic aza-arenes

Chemists from Scripps Research and the University of California, Los Angeles, have developed methods for the precise, flexible modification of a broad class of chemical compounds called bicyclic aza-arenes, which are commonly used to build drug molecules.

9 Aug 2022

MIT researchers develop an easy-to-use test to predict Covid-19 immunity

Most people in the United States have some degree of immune protection against Covid-19, either from vaccination, infection, or a combination of the two. But, just how much protection does any individual person have?

9 Aug 2022

New approach for developing antiviral drugs could slow down future viral outbreaks, save lives

Just as with COVID-19, future viral outbreaks will have plenty of time to spread before a vaccine becomes available. A new approach developed at NTNU can save lives and prevent the need to shut down society.

9 Aug 2022

Research paves the way for therapies to treat or delay preterm labor

Researchers have identified a cause of preterm labor, an enigma that has long challenged researchers. New research published in The Journal of Physiology suggests a protein, called Piezo1, is responsible for regulating the behavior of the uterus.

9 Aug 2022

New simulator quantifies the effect of body posture and stomach motility on drug bioavailability

A common, economic, and easy method of administering drugs is orally, by swallowing a pill or capsule.

9 Aug 2022

New mathematical model of bone renewal predicts the effects of osteoporosis medications

The model, described today in eLife, may help improve outcomes for patients with postmenopausal osteoporosis and reduce the risks of side effects by helping physicians build more personalized treatment regimes.

9 Aug 2022

Aberrant levels of three microRNAs may impair healing in venous ulcers, study shows

The study, which includes the first resource detailing the role of microRNAs in the wound-repair process, shows that aberrant levels of a trio of microRNAs may impair healing in venous ulcers.

9 Aug 2022

Researchers develop a potential way to tackle one of the underlying causes of asthma

A possible way to tackle one of the underlying causes of asthma has been developed by researchers from Aston University and Imperial College London.

9 Aug 2022

Study uncovers how common genetic mutations cause renal cancer

The understanding of the link between common genetic mutations and certain cancers is increasing.

9 Aug 2022

Study finds fewer synthetic cannabinoid poisonings in states with cannabis legalization

Synthetic cannabinoids, dangerous designer drugs known by such street names as K2, Spice or AK-47, appear to have less appeal in states that have legalized the natural form of cannabis.

9 Aug 2022

Experts use tools from artificial intelligence to rapidly identify substances that cause overdose deaths

An automated process based on computer algorithms that can read text from medical examiners' death certificates can substantially speed up data collection of overdose deaths – which in turn can ensure a more rapid public health response time than the system currently used, new UCLA research finds.

9 Aug 2022

Researchers unravel a novel molecular target of eicosapentaenoic acid

Eicosapentaenoic acid (EPA) is an essential nutrient belonging to the omega-3 group of polyunsaturated fatty acids (PUFAs). As the human body cannot synthesize PUFAs, dietary supplements containing EPA are required for normal physiological functions. Found abundantly in natural sources like fish, hemp oil, and linseed oil, EPA is known to exhibit anti-inflammatory, neuroprotective, and cardiovascular protective activities.

9 Aug 2022

Researchers develop a long-acting injectable formulation of the anti-TB drug rifabutin

In 2020, more than 1.5 million people around the world died of tuberculosis, marking the first time in more than a decade that annual TB deaths had increased and demonstrating the global need for better access to treatments.

8 Aug 2022

Overnight EEG studies may help inform care for girls with Rett syndrome

In Rett syndrome, a genetic condition affecting girls almost exclusively, mutations in the MECP2 gene cause a regression of language and motor skills starting at 12 to 18 months of age.

8 Aug 2022

Drugs News and Research

British Heart Foundation funded Surrey project will address cardiac safety in novel anti-malarial agents

Rice University researchers model a key mechanism by which DNA replicates

A broad sarbecovirus-neutralizing antibody cocktail

Neuronal cilia are important for dopamine receptor 1 signaling, study shows

Using microrobotic platforms for endodontic therapy and diagnostics

Dual therapy offers both benefit and risk after common type of cardiac surgery

Scripps, UCLA chemists develop a 'molecular editing' toolkit for modifying bicyclic aza-arenes

MIT researchers develop an easy-to-use test to predict Covid-19 immunity

New approach for developing antiviral drugs could slow down future viral outbreaks, save lives

Research paves the way for therapies to treat or delay preterm labor

New simulator quantifies the effect of body posture and stomach motility on drug bioavailability

New mathematical model of bone renewal predicts the effects of osteoporosis medications

Aberrant levels of three microRNAs may impair healing in venous ulcers, study shows

Researchers develop a potential way to tackle one of the underlying causes of asthma

Study uncovers how common genetic mutations cause renal cancer

Study finds fewer synthetic cannabinoid poisonings in states with cannabis legalization

Experts use tools from artificial intelligence to rapidly identify substances that cause overdose deaths

Researchers unravel a novel molecular target of eicosapentaenoic acid

Researchers develop a long-acting injectable formulation of the anti-TB drug rifabutin

Overnight EEG studies may help inform care for girls with Rett syndrome

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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