Insulin News and Research

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Insulin is a hormone that is needed to convert glucose, starches and other food into energy needed for daily life. Insulin allows cells to use glucose for fuel and is secreted by beta cells in the islets of Langerhans. The release of insulin from the pancreas is stimulated by increased blood glucose, vagal nerve stimulation, and other factors. Insulin is obtained from various animals and available in a variety of preparations. Commercial insulin preparations differ in a number of ways, including differences in the animal species from which they are obtained; their purity, concentration, and solubility; and the time of onset and duration of their biologic action. An oral hypoglycemic agent is not a form of insulin therapy.

Reducing sugar and increasing fiber intake may improve diabetes risk factors in Latino teens

Reducing sugar intake by the equivalent of one can of soda per day and increasing fiber intake by the amount equivalent to one half cup of beans per day appears to improve risk factors associated with type 2 diabetes in Latino adolescents, according to a report in the April issue of Archives of Pediatrics & Adolescent Medicine.

6 Apr 2009

Long-acting insulin analogues in type 2 diabetes: advantage over human insulin not proven

It has so far not been proven that long-acting insulin analogues (LAIAs) have an advantage over conventional human insulin in the treatment of patients with type 2 diabetes.

6 Apr 2009

Bariatric surgery shows potential for resolving type 2 diabetes

As the incidence of obesity-induced type 2 diabetes mellitus continues to increase worldwide, medical research indicates that surgery to reduce obesity can completely eliminate all manifestations of diabetes.

2 Apr 2009

Scientists detect molecular obesity link to insulin resistance, type II diabetes

A molecular switch found in the fat tissue of obese mice is a critical factor in the development of insulin resistance, report scientists at the Salk Institute for Biological Studies.

2 Apr 2009

'Pre-diabetics' face heightened risk of heart disease

The study, published in the Journal of Clinical Endocrinology & Metabolism , was led by Jill P. Crandall, M.D., associate professor of clinical medicine and director of the Diabetes Clinical Trials Unit at Einstein.

2 Apr 2009

Missing link between fructose, insulin resistance found

A new study in mice sheds light on the insulin resistance that can come from diets loaded with high-fructose corn syrup, a sweetener found in most sodas and many other processed foods.

2 Apr 2009

Is telmisartan effective in treating non-alcoholic steatohepatitis?

Non-alcoholic fatty liver disease (NAFLD) and non-alcoholic steatohepatitis (NASH) are well-recognized causes of progressive liver disease leading to cirrhosis and hepatocellular carcinoma.

2 Apr 2009

Drugs that act on 'fasting signal' may curb insulin resistance in obese

A report in the March issue of Cell Metabolism , a Cell Press publication, has found that a signal known to play a role during fasting also switches on early in the fat tissue of obese mice as they progress toward type 2 diabetes.

2 Apr 2009

Discovery of new fat-fighting pathway

Researchers at Albert Einstein College of Medicine of Yeshiva University have discovered a process that controls the amount of fat that cells store for use as a back-up energy source.

1 Apr 2009

Schizophrenics at increased risk for type 2 diabetes

People with schizophrenia are at increased risk for type 2 diabetes, Medical College of Georgia researchers have found.

30 Mar 2009

Medgenics’ phase I/II clinical trial shows EPODURE continuous anemia treatment lasting 5 months in kidney disease patients

Medgenics has announced that the latest, encouraging results of the Company's ongoing EPODURE Biopump Phase I/II Clinical Trial were presented at the 45th Conference of the Israeli Society of Nephrology and Hypertension, in Israel on March 27, 2009.

29 Mar 2009

How fat is stored may explain lower rate of liver disease in African-Americans

Where different ethnic groups store fat in their bodies may account for differences in the likelihood they'll develop insulin resistance and non-alcoholic fatty liver disease, researchers at UT Southwestern Medical Center have found.

29 Mar 2009

Dapagliflozin trial results indicate improvement in key glycemic measures in treatment-naive type 2 diabetes

Findings published in Diabetes Care from a 12-week, Phase IIb dose-ranging study showed that dapagliflozin, a novel, selective, sodium glucose co-transporter2 (SGLT2) inhibitor, produced clinically meaningful reductions across all key glycemic measures studied [glycosylated hemoglobin level (HbA1c), fasting plasma glucose (FPG), and postprandial plasma glucose (PPG)] in treatment-naive type 2 diabetes patients, compared to placebo.

29 Mar 2009

Difference in fat storage may explain lower rate of liver disease in African-Americans

29 Mar 2009

Fructose metabolism by the brain increases food intake and obesity

The journal Biochemical and Biophysical Research Communications (BBRC), published by Elsevier, will publish an important review this week online, by M. Daniel Lane and colleagues at Johns Hopkins, building on the suggested link between the consumption of fructose and increased food intake, which may contribute to a high incidence of obesity and Type 2 diabetes.

25 Mar 2009