Immune System News and Research

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Experts advise against using steroids for treatment of coronavirus

Steroids should be avoided in the treatment of the current novel coronavirus, experts have advised.

6 Feb 2020

New plant-based drug shown to help patients with head and neck cancers

In a UCLA-led phase I clinical trial, a new plant-based drug called APG-157 showed signs of helping patients fight oral and oropharyngeal cancers. These cancers are located in the head and the neck.

5 Feb 2020

Targeting the microenvironment of cancer cells to inhibit tumor growth

The recognition of bacterial infections or foreign substances is mediated and controlled by the human immune system. This innate and adaptive immune system comprises the most important metabolic and cellulare processes to fight against infections and other diseases.

5 Feb 2020

Study may suggest new therapeutic approaches to control immune responses

Researchers have provided new insight on the role of cyclic AMP (cAMP) in regulating the immune response.

5 Feb 2020

Heart muscle cells of zebrafish change their metabolism during heart regeneration

Researchers from the group of Jeroen Bakkers at the Hubrecht Institute have found that the muscle cells in the heart of zebrafish change their metabolism, the way in which they generate energy, during heart regeneration.

5 Feb 2020

Princeton researchers find link between microbes and cancers in threatened California foxes

Can staph microbes lead to cancer? Microbes are known to affect digestion, mood and overall health, and now Princeton researchers have shown that a shift in the microbiome is linked to cancer -- at least in a threatened subspecies of foxes found only on one island off the California coast.

4 Feb 2020

Advanced X-ray combination technique aids tuberculosis and osteoporosis research

With an advanced X-ray combination technique, scientists have traced nanocarriers for tuberculosis drugs within cells with very high precision.

4 Feb 2020

Making it all work: brain-dependent immune activation in embryos

How does the immune system develop its functionality? This has been an ongoing area of research for biologists. Now, a new study published in the journal NPJ Regenerative Medicine in February 2020 shows that in very early fetal life the brain must signal directions to the developing immune system to help it defend the body from infectious agents. This signaling markedly improves the capability of the embryo to survive when faced with bacterial infection.

4 Feb 2020

Hendra antibody trial shows promise in a world-first human clinical trial

The Hendra virus is a potent pathogen transmitted to humans from animals that cause a severe and often fatal illness in both infected horses and humans. Originating from fruit bats, the virus caused an outbreak in Australia in 1994.

4 Feb 2020

Promising HIV vaccine fails in a large-scale clinical trial

The human immune deficiency virus (HIV) is an infectious disease that can lead to immunosuppression called acquired immunodeficiency syndrome (AIDS). For decades, scientists race to discover a vaccine that can help prevent the spread of the virus. The latest trial testing a new experimental vaccine in South Africa end in disappointment after deeming ineffective in preventing infection.

4 Feb 2020

FDA-approved OIT product marks major milestone in management of peanut allergies

In February 2020, the U.S. Food and Drug Administration (FDA) approved Palforzia, the first peanut powder product designed to help reduce the risk of severe peanut-induced allergic reactions through desensitization over time.

4 Feb 2020

New step toward understanding cancer prevention in evolutionary terms

A new Scientific Reports paper puts an evolutionary twist on a classic question. Instead of asking why we get cancer, Leonardo Oña of Osnabrück University and Michael Lachmann of the Santa Fe Institute use signaling theory to explore how our bodies have evolved to keep us from getting more cancer.

4 Feb 2020

Researchers develop an emergency stop switch for CAR T-cell therapies

Immunotherapy, unlike chemotherapy and radiotherapy, arms the body's immune system to attack cancer cells. In recent years, it has proven to be remarkably successful at treating leukemia, lymphoma and other liquid cancers, or cancers present in body fluids.

4 Feb 2020

Many older people in Australia are missing out on shingles vaccination

Many older Australians are missing out on the chance to get vaccinated against shingles, according to the latest edition of Australian Prescriber.

3 Feb 2020

Researchers develop novel therapeutic approach to cure chronic hepatitis B

Researchers at Helmholtz Zentrum München, Technical University of Munich (TUM) and the German Center for Infection Research have developed a novel therapeutic approach to cure chronic hepatitis B.

3 Feb 2020

HIV antibody therapy improves immune function

A new study published in the journal Nature Medicine in February 2020 reports that the administration of neutralizing antibodies against HIV improve the recipient’s specific T cell responses against the virus.

3 Feb 2020

Blood test can be used to gauge a person's risk for cerebral small vessel disease

A UCLA-led study has found that levels of six proteins in the blood can be used to gauge a person's risk for cerebral small vessel disease, or CSVD, a brain disease that affects an estimated 11 million older adults in the U.S. CSVD can lead to dementia and stroke, but currently it can only be diagnosed with an MRI scan of the brain.

3 Feb 2020

FDA gives clearance to IND application for Calibr's 'switchable' CAR-T cell therapy

Calibr, the drug discovery and development division of Scripps Research, today announced that the U.S. Food and Drug Administration has given clearance to the Investigational New Drug (IND) application for Calibr's "switchable" CAR-T cell therapy, which is being evaluated for the treatment of certain cancers, including relapsed/refractory B-cell malignancies such as non-Hodgkin lymphoma and chronic lymphocytic leukemia.

3 Feb 2020

Experimental vaccine prevents infection of lung and nasal cavity

Researchers have found that viruses causing human respiratory infections called human metapneumovirus (HMPV) have a special ability to hide itself from the body’s immune system. This prevents the body from fighting the infection off. This very strategy has been used in development of a vaccine against HMPV say the researchers.

3 Feb 2020

Discovery about how cancer cells hide from the immune system could improve treatments

Researchers have shed light on the mechanism through which cancer cells become camouflaged to escape immune system detection and attack.

31 Jan 2020

Immune System News and Research

Experts advise against using steroids for treatment of coronavirus

New plant-based drug shown to help patients with head and neck cancers

Targeting the microenvironment of cancer cells to inhibit tumor growth

Study may suggest new therapeutic approaches to control immune responses

Heart muscle cells of zebrafish change their metabolism during heart regeneration

Princeton researchers find link between microbes and cancers in threatened California foxes

Advanced X-ray combination technique aids tuberculosis and osteoporosis research

Making it all work: brain-dependent immune activation in embryos

Hendra antibody trial shows promise in a world-first human clinical trial

Promising HIV vaccine fails in a large-scale clinical trial

FDA-approved OIT product marks major milestone in management of peanut allergies

New step toward understanding cancer prevention in evolutionary terms

Researchers develop an emergency stop switch for CAR T-cell therapies

Many older people in Australia are missing out on shingles vaccination

Researchers develop novel therapeutic approach to cure chronic hepatitis B

HIV antibody therapy improves immune function

Blood test can be used to gauge a person's risk for cerebral small vessel disease

FDA gives clearance to IND application for Calibr's 'switchable' CAR-T cell therapy

Experimental vaccine prevents infection of lung and nasal cavity

Discovery about how cancer cells hide from the immune system could improve treatments

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