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Scientists isolate potent SARS-CoV-2 neutralizing antibodies from COVID-19 patients

Researchers at Columbia University Irving Medical Center have isolated antibodies from several COVID-19 patients that, to date, are among the most potent in neutralizing the SARS-CoV-2 virus.

22 Jul 2020

Vitamin D could help suppress excessive T cell-mediated lung inflammation in severe COVID-19

As COVID-19 continues to spread over the world scientists continue to seek the reasons for the difference in disease severity from person to person.

22 Jul 2020

Study captures unexpected features of SARS-Cov-2 spike protein

The rod-like spike proteins on the surface of SARS CoV-2 are the tip of the spear of the COVID-19 pandemic.

22 Jul 2020

Mouse model of fatal COVID-19 developed for vaccine and drug testing

Now, a new study published on the preprint server bioRxiv in July 2020 presents an engineered transgenic mouse that reproduces the functional and clinical characteristics of severe human SARS-CoV-2 infection.

21 Jul 2020

Researchers demonstrate the production of viral parts within artificial cells

Scientists searching for better diagnostic tests, drugs or vaccines against a virus must all begin by deciphering the structure of that virus.

21 Jul 2020

Fasting-mimicking diet along with hormone therapy could help treat breast cancer

A USC-led team of scientists has found that a fasting-mimicking diet combined with hormone therapy has the potential to help treat breast cancer, according to newly published animal studies and small clinical trials in humans.

21 Jul 2020

Exploring how bacteria and viruses coexist inside the human gut

The adage "all things in moderation" applies not to just to food and drink, but also to the legions of bacteria inside our guts helping us digest that food and drink. It turns out the rule may also extend to the lesser understood bacteriophages, which are viruses that infect the bacteria living inside us.

21 Jul 2020

Pfizer/BioNTech COVID-19 vaccine elicits both neutralizing antibodies and T cell response

A new study published on the preprint server medRxiv by a research group from the U.S. and Germany indicates that a novel BNT162b1 RNA-based vaccine against coronavirus disease (COVID-19) induces functional and proinflammatory T cell responses in almost all participants – marking another landmark achievement for this promising vaccine candidate.

21 Jul 2020

RUB neuroscientists assess neuronal activity during stimulation-based learning process

Stimulating the fingertip rhythmically for a sustained period of time, markedly improves touch sensitivity of this finger. A research team led by Associate Professor Dr. Hubert Dinse at Ruhr-Universität Bochum analyzed the impact of this process in the brain.

21 Jul 2020

Antibody profile and estimated seroprevalence in COVID-19 infection

A new Swedish study published on the preprint server medRxiv in July 2020 describes the results of using highly sensitive and specific anti-spike antibody tests in a cohort of patients with COVID-19 over a range of disease severity.

21 Jul 2020

Analysis of the SARS-CoV-2 proteome via visual tools

Now, a new study published on the preprint server bioRxiv* in July 2020 shows how this can be advanced at a greater speed by combining experimental results with homology models obtained by high-throughput pipelines. This will help produce new hypotheses that will show novel druggable targets for effective drug development.

21 Jul 2020

A multi-omics single cell analysis on COVID-19

Now, a new study published on the preprint server medRxiv aims to analyze the immune response over time, using multi-omics in the study of a single cell.

21 Jul 2020

Involvement of nicotine receptors in COVID-19

Researchers from the University of Bristol, Oxford Brookes University and the University of California San Diego neatly demonstrated how the spike protein of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) exhibits high affinity for nicotinic acetylcholine receptors (nAChRs), with significant implications for coronavirus disease (COVID-19) pathology and infectivity. Their findings are published on the bioRxiv* preprint server.

20 Jul 2020

UC Davis Health evaluates new antibody cocktail as a possible treatment for COVID-19

Timothy Albertson, chair of internal medicine and specialist in pulmonary and critical care, is leading efforts at UC Davis Health to test a new antibody cocktail (REGN-COV2) as a prevention and treatment for COVID-19.

20 Jul 2020

Experimental therapy slows zika replication and prevents microcephaly in mice

An international group of researchers have discovered that inhibiting AHR (aryl hydrocarbon receptor), a protein with roles in regulating immunity, stem cell maintenance and cellular differentiation, enables the immune system to combat replication of zika virus in the organism far more effectively.

20 Jul 2020

Novel blood test for heart failure could lead to new diagnostics for COVID-19 patients

A new blood test that reliably predicts outcomes for heart failure patients could lead to new diagnostics and treatments for COVID-19 patients as well, according to newly published research from cardiologists at the University of Alberta.

20 Jul 2020

How immune cells switch to attack mode

Unraveling a key motif: The T lymphocytes of the immune system work to destroy infected cells or cancer cells. To do so, they have to identify the threat: Molecules perceived as foreign - so-called antigens - bind to the T-cell receptor on the T cell surface.

20 Jul 2020

Researchers develop new nano drug that kills triple-negative breast cancer cells

Researchers at the University of Arkansas have developed a new nano drug candidate that kills triple negative breast cancer cells.

20 Jul 2020

Examining cardiovascular injuries in patients who recovered from COVID-9 infection

The coronavirus disease is wreaking havoc on the health of communities throughout the world and may have lasting cardiac effects on those who have recovered from the virus.

19 Jul 2020

Researchers are producing COVID-19 spike proteins to prevent future infections

On July 1, the Texas A&M Engineering Experiment Station's National Center for Therapeutics Manufacturing received funding from the National Institute for Innovation in Manufacturing Biopharmaceuticals to help find a way to prevent the SARS-CoV-2 virus from binding to cells, protecting people from future infections.

19 Jul 2020

Receptor News and Research

Scientists isolate potent SARS-CoV-2 neutralizing antibodies from COVID-19 patients

Vitamin D could help suppress excessive T cell-mediated lung inflammation in severe COVID-19

Study captures unexpected features of SARS-Cov-2 spike protein

Mouse model of fatal COVID-19 developed for vaccine and drug testing

Researchers demonstrate the production of viral parts within artificial cells

Fasting-mimicking diet along with hormone therapy could help treat breast cancer

Exploring how bacteria and viruses coexist inside the human gut

Pfizer/BioNTech COVID-19 vaccine elicits both neutralizing antibodies and T cell response

RUB neuroscientists assess neuronal activity during stimulation-based learning process

Antibody profile and estimated seroprevalence in COVID-19 infection

Analysis of the SARS-CoV-2 proteome via visual tools

A multi-omics single cell analysis on COVID-19

Involvement of nicotine receptors in COVID-19

UC Davis Health evaluates new antibody cocktail as a possible treatment for COVID-19

Experimental therapy slows zika replication and prevents microcephaly in mice

Novel blood test for heart failure could lead to new diagnostics for COVID-19 patients

How immune cells switch to attack mode

Researchers develop new nano drug that kills triple-negative breast cancer cells

Examining cardiovascular injuries in patients who recovered from COVID-9 infection

Researchers are producing COVID-19 spike proteins to prevent future infections

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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