Clinical Trial News and Research

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Phase I clinical trial of HIV vaccines to begin in the U.S.

A Phase I clinical trial testing the safety of vaccines that might have the potential to prevent HIV infection will begin this month at four sites in the United States, marking the latest step in a three-decade quest at UMass Medical School to harness the power of DNA vaccines in addressing a major global health threat.

28 Mar 2018

Vagus nerve stimulation accelerates motor skill recovery after stroke

Researchers at The University of Texas at Dallas have demonstrated a method to accelerate motor skill recovery after a stroke by helping the brain reorganize itself more quickly.

28 Mar 2018

New intervention aims to improve treatment adherence among teen kidney transplant recipients

Learning to become self-sufficient and responsible is part of life's journey through the teen and young adult years. Mistakes are often made, and lessons are learned. However, for young kidney-graft patients, any mistake or failure in keeping to their strict immunosuppressive therapy can lead to tragic results.

27 Mar 2018

Combination therapy effectively induces tumor cell death and reduces spread of breast cancer

Each day, normal human cell tissues express a protein known as p53 that wages war against potential malignancies. However, between 30 and 40 percent of human breast cancers express a defective (mutant) form of p53 that helps cancer cells proliferate and grow.

27 Mar 2018

Lung transplant drug enters clinical trial after decades of research

In the culmination of decades of research at the University of Virginia Health System, doctors have begun human testing of a drug they hope will one day save many lives among lung transplant recipients.

26 Mar 2018

Two immunotherapies used together for the first time to fight against solid tumors

Two immunotherapies - one that enables the T-cells a patient already has to better attack a tumor and another that can produce an independent and vigorous immune response - are being given together for the first time to help more patients wage a stronger war on a wide range of solid tumors, researchers say.

26 Mar 2018

Researchers identify potential obesity treatment in freezing hunger-signaling nerve

Researchers developed this treatment for patients with mild-to-moderate obesity to reduce the attrition that is common with weight-loss efforts.

23 Mar 2018

Bio-Optronics and Synexus announce partnership to improve global research operations

Bio-Optronics, the creator of the market-leading Clinical Conductor Clinical Trial Management System announces a new partnership with Synexus, the world’s largest site network organization.

From AES - Accelerated Enrollment Solutions 23 Mar 2018

Certain nutrients found in food may help reduce symptoms of psychotic illness

A scientific paper has revealed that some nutrients found in food may help reduce the symptoms of psychotic illness, when used in the early stages of treatment.

22 Mar 2018

Gut microbiome may promote pancreatic cancer by inducing immune suppression

Bacterial load was significantly higher in pancreatic tumor samples from patients with pancreatic ductal adenocarcinoma compared with pancreatic tissue from normal individuals, and in studies using mice, eliminating certain "bad" bacteria slowed the growth of pancreatic cancer, reversed immune suppression, and upregulated the immune checkpoint protein PD1.

22 Mar 2018

Neem Biotech to share findings on cystic fibrosis biofilm disruption at ECFS Basic Science Conference

Neem Biotech, a Wales-based R&D biotech working in the field of novel antimicrobial drug development, announced today that it will be presenting results of its ongoing development work into the impact of NX-AS-401, its lead candidate,on biofilms in chronic cystic fibrosis lung infections at the 15th European Cystic Fibrosis Basic Science Conference taking place from 21st to 24th March 2018 in LoutrakiKorinthias, Greece.

From Neem Biotech 22 Mar 2018

Anticoagulant drugs found safe to use in patients undergoing surgery for irregular heartbeat

A trial led by the University of Birmingham has found that two types of blood thinning drugs are safe to use in patients with an irregular heartbeat when they are undergoing surgery aimed at stopping the condition.

21 Mar 2018

Hydrogel may accelerate healing of diabetic ulcers

A hydrogel invented at Rice University that is adept at helping the body heal may also be particularly good at treating wounds related to diabetes.

20 Mar 2018

Adjuvant AC chemotherapy found to be effective in treating HRD-positive breast cancer patients

People with tough-to-treat triple negative breast cancer, whose tumors also don't allow for double-strand DNA repair, fare better when treated with a common adjuvant breast cancer chemotherapy combination, according to results from a SWOG clinical trial.

20 Mar 2018

Quintupling inhaled steroid doses may not benefit children with asthma

Children with mild to moderate asthma do not benefit from a common practice of increasing their inhaled steroids at the first signs of an asthma exacerbation, according to clinical trial results published in The New England Journal of Medicine.

20 Mar 2018

Stem cell-derived ocular cells treat severe AMD

In July 2015, 86-year-old Douglas Waters developed severe age-related macular degeneration (AMD). He struggled to see things clearly, even when up close.

19 Mar 2018

Changes in the intestines may be responsible for reversal of diabetes after bariatric surgery

A new study helps explain changes in the intestines that may be responsible for the reversal of diabetes in people who undergo a type of bariatric surgery known as Roux-en-Y gastric bypass surgery.

19 Mar 2018

Viagra cuts colorectal cancer risk in animal model

A small, daily dose of Viagra significantly reduces colorectal cancer risk in an animal model that is genetically predetermined to have the third leading cause of cancer death, scientists report.

19 Mar 2018

Stem cell treatment may help rejuvenate ovaries, avoid effects of premature menopause

Young women with premature ovarian insufficiency may be able to use their own bone marrow stem cells to rejuvenate their ovaries and avoid the effects of premature menopause, new research suggests.

19 Mar 2018

Multi-center study to evaluate promising new intervention for upper limb dysfunction after SCI

Kessler Foundation has been awarded an $857,600 sub-award from the Department of Health and Human Services, Administration for Community Living, National Institute on Disability, Independent Living, and Rehabilitation Research, to study a promising new intervention for upper limb dysfunction after spinal cord injury (SCI).

16 Mar 2018

Clinical Trial News and Research

Phase I clinical trial of HIV vaccines to begin in the U.S.

Vagus nerve stimulation accelerates motor skill recovery after stroke

New intervention aims to improve treatment adherence among teen kidney transplant recipients

Combination therapy effectively induces tumor cell death and reduces spread of breast cancer

Lung transplant drug enters clinical trial after decades of research

Two immunotherapies used together for the first time to fight against solid tumors

Researchers identify potential obesity treatment in freezing hunger-signaling nerve

Bio-Optronics and Synexus announce partnership to improve global research operations

Certain nutrients found in food may help reduce symptoms of psychotic illness

Gut microbiome may promote pancreatic cancer by inducing immune suppression

Neem Biotech to share findings on cystic fibrosis biofilm disruption at ECFS Basic Science Conference

Anticoagulant drugs found safe to use in patients undergoing surgery for irregular heartbeat

Hydrogel may accelerate healing of diabetic ulcers

Adjuvant AC chemotherapy found to be effective in treating HRD-positive breast cancer patients

Quintupling inhaled steroid doses may not benefit children with asthma

Stem cell-derived ocular cells treat severe AMD

Changes in the intestines may be responsible for reversal of diabetes after bariatric surgery

Viagra cuts colorectal cancer risk in animal model

Stem cell treatment may help rejuvenate ovaries, avoid effects of premature menopause

Multi-center study to evaluate promising new intervention for upper limb dysfunction after SCI

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