Immune System News and Research

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New combination treatment could help fight advanced melanoma

A study by researchers at the UCLA Jonsson Comprehensive Cancer Center suggests that using an immunotherapy drug called NKTR-214, also known as bempegaldesleukin, in combination with an infusion of anti-tumor immune cells, or T cells, may produce a stronger immune response that could help fight advanced melanoma.

31 Jan 2020

Multimodal analysis of tumors could give new insights into treating cancer patients

Melding the genetic and cellular analysis of tumors with how they appear in medical images could give physicians and other cancer therapy specialists new insights into how to best treat patients, especially those with brain cancer, according to a new study led by the Translational Genomics Research Institute, an affiliate of City of Hope.

31 Jan 2020

Modified form of poliovirus shows potential as cancer vaccine in animal studies

A modified form of poliovirus, pioneered at Duke Cancer Institute as a therapy for glioblastoma brain tumors, appears in laboratory studies to also have applicability for pediatric brain tumors when used as part of a cancer vaccine.

31 Jan 2020

IU researchers receive $3 million NIH grants to study cell functions in the bone marrow

More than $3 million from the National Institutes of Health will allow Indiana University Melvin and Bren Simon Cancer Center researchers to improve understanding of the complex system of how hematopoietic stem cells survive and sustain their function in the bone marrow.

31 Jan 2020

Researchers locate specific mutation in the gene responsible for Chédiak-Higashi syndrome

Humans and animals are made up of trillions of cells, and each cell contains DNA specific to that individual. Therefore, identifying DNA that causes genetic disorders gives researchers and clinicians a better understanding of how to treat inherited diseases and possibly prevent the diseases from being passed down to future generations.

30 Jan 2020

Turning stink into therapy for atherosclerosis

In an amusing but amazing turnaround, it seems the most foul-smelling compound on earth, called putrescine, could help relieve chronic inflammation, most importantly in the arterial thickening called atherosclerosis. This discovery is reported in the journal Cell Metabolism in January 2020.

30 Jan 2020

Scientists reveal clinical features of Wuhan coronavirus patients

The Wuhan coronavirus, or the 2019-nCoV, which originated in Wuhan City in Hubei province infected more than 7,700 people with the death toll topping more than 170. China reports 38 deaths in just 24 hours, making the outbreak one of the deadliest ones the country has faced.

30 Jan 2020

Rapid weather variability could increase risk of a flu epidemic

New research from a team of Florida State University scientists shows that rapid weather variability as a result of climate change could increase the risk of a flu epidemic in some highly populated regions in the late 21st century.

30 Jan 2020

Researchers discover new target for repairing heart after heart attack

Billions of cardiac muscle cells are lost during a heart attack. The human heart cannot replenish these lost cells, so the default mechanism of repair is to form a cardiac scar.

30 Jan 2020

New target protein linked to regulation, movement of tumor-associated macrophages

Developing a therapy to combat cancer remains one of the most difficult challenges in medical research. Cancer owes its notorious identity to the fact that the cancer cells use the host's own immune system to grow and spread, ultimately becoming deadly.

30 Jan 2020

Study may help develop ibrutinib-based combination therapies for blood cancer

Chronic lymphocytic leukemia (CLL) is the most common form of blood cancer (leukemia) in the Western world, affecting approximately 1.2% of all cancer patients.

30 Jan 2020

Study opens up strategies for early diagnosis, treatment of diseases linked to chronic inflammation

Claudio Franceschi, a world-renowned scientist, professor at the University of Bologna (Italy) and head of the Research Laboratory for Systems Medicine of Healthy Aging at Lobachevsky University, together with other members of an international research team, has described the mechanisms underlying chronic inflammation and identified several risk factors leading to disease.

29 Jan 2020

Study reveals how the gut's protective mechanisms ramp up with food intake

A new study has revealed how the gut's protective mechanisms ramp up significantly with food intake, and at times of the day when mealtimes are anticipated based on regular eating habits.

29 Jan 2020

Research project moves one step closer to personalized treatment of rheumatic diseases

When a patient is diagnosed with rheumatoid arthritis, psoriatic arthritis or spondyloarthritis, prescribing the correct type of medicine is a case of trial and error.

29 Jan 2020

New way to treat stroke using an already FDA-approved drug shows promise

Stroke is the third leading cause of death and disability in the United States. More than 87 percent are ischemic strokes, caused by obstruction of one or more cerebral arteries. With limited progress in developing treatments, there is a critical need for neuroprotective agents to effectively treat stroke.

29 Jan 2020

Immune System News and Research

New combination treatment could help fight advanced melanoma

Multimodal analysis of tumors could give new insights into treating cancer patients

Modified form of poliovirus shows potential as cancer vaccine in animal studies

IU researchers receive $3 million NIH grants to study cell functions in the bone marrow

Researchers locate specific mutation in the gene responsible for Chédiak-Higashi syndrome

Turning stink into therapy for atherosclerosis

Scientists reveal clinical features of Wuhan coronavirus patients

Rapid weather variability could increase risk of a flu epidemic

Researchers discover new target for repairing heart after heart attack

New target protein linked to regulation, movement of tumor-associated macrophages

Study may help develop ibrutinib-based combination therapies for blood cancer

Study opens up strategies for early diagnosis, treatment of diseases linked to chronic inflammation

Study reveals how the gut's protective mechanisms ramp up with food intake

Research project moves one step closer to personalized treatment of rheumatic diseases

New way to treat stroke using an already FDA-approved drug shows promise

Time to include standard care screenings for diagnosis of pre-symptomatic type 1 diabetes

New therapeutic strategy to fight against advanced melanoma

Bavarian research network aims to develop new approaches against multi-resistant pathogens

Groundbreaking study to investigate why cancer returns in some people and not others

New guidance will help improve outcomes for patients with hyperthyroidism

Understanding the DNA Damage Response in Innate Immunity eBook

How ELRIG Is Helping Mid-Career Scientists Navigate Leadership, Career Change and Redundancy

The role of UV-Vis in biopharma QC

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