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Metabolic derangement may facilitate cell proliferation in PAH

An enzyme that facilitates modification of proteins via a glucose metabolism pathway may promote cell proliferation in the lung tissue of patients with idiopathic pulmonary arterial hypertension, say researchers.

13 Mar 2015

Tablet use has implications for potential neck injury

Tablet use has rocketed. Last year in the US, for example, 42% of under 18's owned one and more than half of 35-49 year olds used them regularly.

13 Mar 2015

Study shows fatigue pathways are more sensitive in patients with chronic fatigue syndrome

The mechanism that causes high-performance athletes to "feel the burn" turns out to be the culprit in what makes people with chronic fatigue syndrome feel exhausted by the most common daily activities, new University of Florida Health research shows.

13 Mar 2015

Neuralstem reports top line data from NSI-566 Phase II trial for treatment of ALS

Neuralstem, Inc. announced top line data from the Phase II trial of NSI-566 spinal cord-derived neural stem cells under development for the treatment of amyotrophic lateral sclerosis (ALS). The study met primary safety endpoints. The maximum tolerated dose of 16 million transplanted cells and the surgery was well tolerated.

12 Mar 2015

Organ-on-a-chip could replace use of animals to test drugs for safety and efficacy

When University of California, Berkeley, bioengineers say they are holding their hearts in the palms of their hands, they are not talking about emotional vulnerability.

12 Mar 2015

European scientists identify gene linked with certain types of early-onset epilepsy

Certain types of early-onset epilepsy are caused by previously unknown mutations of a potassium channel gene, KCNA2. The mutations disrupt the electrical balance in the brain in two ways. In some patients, the flow of potassium is greatly reduced; while in others, it is raised enormously. Both states can lead to hard-to-treat epileptic seizures. Mental and motor development can come to a stop, or even to regress.

12 Mar 2015

Early mobility therapy improves outcomes of patients with acute respiratory distress syndrome

Acute respiratory distress syndrome (ARDS) is a life-threatening lung condition that affects approximately 200,000 people a year in the United States and has a higher mortality rate than breast and prostate cancer combined. The condition most often occurs in people who are critically ill or who have significant injuries; those who do survive it often experience profound skeletal muscle weakness.

12 Mar 2015

Excess dietary sodium can adversely affect organs

You may think you're one of the lucky ones who can eat all the salty snacks and convenience foods you want and still register low numbers on the blood pressure cuff. But, new research suggests you may not be so lucky after all.

11 Mar 2015

Scientists develop mathematical model to digitally map communication between heart cells

A team of scientists led by Johns Hopkins cardiologist and biomedical engineer Hiroshi Ashikaga, M.D., Ph.D., has developed a mathematical model to measure and digitally map the beat-sustaining electrical flow between heart cells.

11 Mar 2015

Narcolepsy bears trademarks of classic autoimmune disorder

Narcoleptics suffer from bouts of sleepiness and sleep attacks, which impair their ability to function in daily life. But the precise cause of narcolepsy has long eluded scientists, and the cure for the devastating neurological disorder afflicting an estimated three million people worldwide -- and one in 3,000 Americans -- remains at bay.

10 Mar 2015

Using IT devices may put your muscles and joints under particular strain

Spending hours on a computer or sending lots of text messages on a mobile phone can result in a stiff neck and sometimes even a strained thumb. Computer scientists in Saarbrücken have developed a procedure that simulates in a lifelike manner which muscles and joints are put under particular strain when using IT devices. It also demonstrates the speed and accuracy with which a user can operate a device.

10 Mar 2015

Testosterone, estrogen raise men's risk of heart disease

Why men have more heart disease than premenopausal women has been unclear, but a new study shows that the sex hormones testosterone and estrogen alter cardiovascular risk factors in a way that raises a man's risk of heart disease.

9 Mar 2015

New study shows positive effects of gastric bypass surgery on obese adolescents

The skeletons of obese adolescents are usually more dense than those of normal weight teens, but after gastric bypass surgery, most return to normal density within two years, a new study finds.

9 Mar 2015

Obese females with eating/behavioral characteristic have impaired metabolism

In obese females, a close relationship may exist between their disinhibition (detrimental eating and behavioral characteristics) that limits successful weight loss, and impaired metabolism, new research shows.

9 Mar 2015

Researchers study safety, effectiveness of experimental Ebola vaccine following high-risk exposure

A physician who received an experimental Ebola vaccine after experiencing a needle stick while working in an Ebola treatment unit in Sierra Leone did not develop Ebola virus infection, and there was strong Ebola-specific immune responses after the vaccination, although because of its limited use to date, the effectiveness and safety of the vaccine is not certain, according to a study appearing in JAMA.

6 Mar 2015

Plant molecule helps female mice combat weight gain

A molecule found in some plants can combat weight gain induced by a high-fat diet, but only in female mice, not males. 7,8-dihydroxyflavone (7,8-DHF) is thought to mimic the effects of a growth factor induced by exercise.

6 Mar 2015

RBFox2 protein plays critical role in heart failure

Researchers at the University of California, San Diego School of Medicine have identified a key piece in the complex molecular puzzle underlying heart failure - a serious and sometimes life-threatening disorder affecting more than 5 million Americans.

5 Mar 2015

Valley Hospital becomes first hospital in New Jersey to use minimally-invasive approach to treat PAD

The Valley Hospital today announced it was the first hospital in New Jersey to use a recently approved device to offer a minimally-invasive approach to the treatment of peripheral artery disease (PAD) in the upper leg, a serious and common condition associated with an increased risk for heart attack and stroke.

5 Mar 2015

New study assesses suicide risks in older, white males with advanced bladder cancer

Older, single white males with advanced bladder cancer have the highest suicide risk among those with other cancers of the male genitals and urinary system, researchers report.

5 Mar 2015

Study: Omega-3 fatty acids appear to protect heart function among heart attack survivors

Taking omega-3 fatty acids appeared to lower inflammation and guard against further declines in heart function among recent heart attack survivors already receiving optimal standard care, according to results from a randomized, controlled trial to be presented at the American College of Cardiology's 64th Annual Scientific Session in San Diego.

5 Mar 2015

Muscle News and Research

Metabolic derangement may facilitate cell proliferation in PAH

Tablet use has implications for potential neck injury

Study shows fatigue pathways are more sensitive in patients with chronic fatigue syndrome

Neuralstem reports top line data from NSI-566 Phase II trial for treatment of ALS

Organ-on-a-chip could replace use of animals to test drugs for safety and efficacy

European scientists identify gene linked with certain types of early-onset epilepsy

Early mobility therapy improves outcomes of patients with acute respiratory distress syndrome

Excess dietary sodium can adversely affect organs

Scientists develop mathematical model to digitally map communication between heart cells

Narcolepsy bears trademarks of classic autoimmune disorder

Using IT devices may put your muscles and joints under particular strain

Testosterone, estrogen raise men's risk of heart disease

New study shows positive effects of gastric bypass surgery on obese adolescents

Obese females with eating/behavioral characteristic have impaired metabolism

Researchers study safety, effectiveness of experimental Ebola vaccine following high-risk exposure

Plant molecule helps female mice combat weight gain

RBFox2 protein plays critical role in heart failure

Valley Hospital becomes first hospital in New Jersey to use minimally-invasive approach to treat PAD

New study assesses suicide risks in older, white males with advanced bladder cancer

Study: Omega-3 fatty acids appear to protect heart function among heart attack survivors

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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