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Are you and your primary care doc ready to talk about your DNA?

If you have a genetic mutation that increases your risk for a treatable medical condition, would you want to know? For many people the answer is yes. But such information is not commonly part of routine primary care.

22 May 2018

ToolGen's CRISPR/Cas9 gene editing platform improves T-cell anti-tumor activity in mouse model

ToolGen, Inc., a biotechnology company specializing in genome editing, today announced data demonstrating that blocking a molecular pathway that down-regulates T-cell activity with the Company’s CRISPR/Cas9 gene editing platform results in increased T-cell receptor signaling, in vitro, and in improved anti-tumor activity when tested against in a mouse glioblastoma tumor model.

22 May 2018

CRISPR-Cas9-based strategy allows researchers to precisely alter hundreds of different genes

Geneticists have been using model organisms ranging from the house mouse to the single-cell bakers' yeast, Saccharomyces cerevisiae, to study basic biological processes that regulate human development and physiology, and that can be compromised in various diseases.

22 May 2018

Scientists identify new drug target to combat chikungunya virus

Scientists have identified a molecule found on human cells and some animal cells that could be a useful target for drugs against chikungunya virus infection and related diseases, according to new research published in the journal Nature.

21 May 2018

Scientists collate evidence for mismatch between past evolutionary adaptation and modern lives

The transition to modernity - largely driven by the Industrial Revolution - provided us with easier access to food and clean water, with antibiotics, vaccines, and modern medicine.

21 May 2018

Study brings fresh insights into biology of malaria parasite

A team of researchers led by a University of California, Riverside, scientist has found that various stages of the development of human malaria parasites, including stages involved in malaria transmission, are linked to epigenetic features and how chromatin -- the complex of DNA and proteins within the nucleus -- is organized and structured in these parasites.

18 May 2018

New CRISPR/Cas9 system targets regulatory genes of AIDS virus

By destroying the regulatory genes of the AIDS virus HIV-1 using the genome editing system CRISPR/Cas9, a Japanese research group has succeeded in blocking the production of HIV-1 by infected cells.

18 May 2018

Scientists identify new potential target to combat acute myeloid leukemia

AML is not a single disease. It is a group of leukemias that develop in the bone marrow from progenitors of specialized blood cells, the so-called myeloid cells. Rapidly growing and dividing, these aberrant cells crowd the bone marrow and bloodstream, which can be fatal within weeks or months if the disease is left untreated.

18 May 2018

Whole genome sequencing could prevent transfusion reactions

Researchers have recently published a study which may reduce complications and save lives for blood transfusion recipients.

18 May 2018

Scientists discover how unusually long strands of RNA help colon cancer cells avoid death

Researchers from Case Western Reserve University School of Medicine have discovered how unusually long strands of RNA help colon cancer cells avoid death, allowing unregulated growth.

17 May 2018

ECDC whole genome sequencing study helps understand prevalence of drug-resistant gonorrhea

Can whole genome sequencing illustrate changes in drug susceptibility of gonorrhoea to antimicrobials used for treatment and so help to define more effective treatment regimens? The first study of this kind within an international surveillance programme for sexually transmitted infections shows distribution of drug-resistant gonorrhoea strains across Europe.

17 May 2018

Mayo Clinic researchers identify new possible treatment choice for triple negative breast cancer

In a recent study published in the Journal of Clinical Investigation, Mayo Clinic researchers identified that an FDA drug approved for myelodysplastic syndrome may be useful to treat triple-negative breast cancer, which is one of the most aggressive and lethal types of breast cancer.

16 May 2018

DDN and Parabricks announce integrated technology solution that accelerates genome analysis

DDN Storage and Parabricks today announced the availability of a jointly-integrated technology solution that provides massive acceleration for analysis of human genomes.

16 May 2018

Study illuminates how neuronal activity leads to gene activation

From burning your palm on a hot pan handle to memorizing the name of a new acquaintance, "anytime you experience something, your neurons are active," says Kelsey Tyssowski, a graduate student in genetics at Harvard Medical School.

16 May 2018

First genomic survey of gonorrhea maps antibiotic resistance across Europe

The first European-wide genomic survey of gonorrhea has mapped antibiotic resistance in this sexually transmitted disease throughout the continent.

16 May 2018

New method generates detailed 3D images of the body's cancer cells

Making tumor cells glow: Medical physicists at Martin Luther University Halle-Wittenberg (MLU) have developed a new method that can generate detailed three-dimensional images of the body's interior.

16 May 2018

Scientists find overlap between causes of RA and Huntington’s disease

Using new analytic tools, researchers at University of California San Diego School of Medicine and the Icahn School of Medicine at Mount Sinai have decoded the epigenetic landscape for rheumatoid arthritis (RA), a common autoimmune disease that affects more than 1.3 million Americans.

15 May 2018

Genome News and Research

Are you and your primary care doc ready to talk about your DNA?

ToolGen's CRISPR/Cas9 gene editing platform improves T-cell anti-tumor activity in mouse model

CRISPR-Cas9-based strategy allows researchers to precisely alter hundreds of different genes

Scientists identify new drug target to combat chikungunya virus

Scientists collate evidence for mismatch between past evolutionary adaptation and modern lives

Study brings fresh insights into biology of malaria parasite

New CRISPR/Cas9 system targets regulatory genes of AIDS virus

Scientists identify new potential target to combat acute myeloid leukemia

Whole genome sequencing could prevent transfusion reactions

Scientists discover how unusually long strands of RNA help colon cancer cells avoid death

ECDC whole genome sequencing study helps understand prevalence of drug-resistant gonorrhea

Mayo Clinic researchers identify new possible treatment choice for triple negative breast cancer

DDN and Parabricks announce integrated technology solution that accelerates genome analysis

Study illuminates how neuronal activity leads to gene activation

First genomic survey of gonorrhea maps antibiotic resistance across Europe

New method generates detailed 3D images of the body's cancer cells

Scientists find overlap between causes of RA and Huntington’s disease

Nuffield Council on Bioethics outlines ethical issues arising from use of AI in healthcare

Genetic fixer-uppers could aid in predicting prognosis of patients with bladder cancer

Researchers lab-test molecule that may combat common cold virus

Genetics & Genomics - Second Edition eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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