Research News and Research

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Data on health-related quality of life often not collected for investigational cancer drugs

A recent analysis from Canada found that information on health-related quality of life is often not collected for investigational cancer drugs or used to calculate the balance of costs and benefits of these drugs when they are submitted for reimbursement, according to findings published early online in CANCER, a peer-reviewed journal of the American Cancer Society.

23 Sep 2019

IDSA calls for meaningful funding to control current Ebola outbreak

Spending bills released by Senate Appropriations Committee Wednesday demonstrate encouraging recognition of some of the most urgent health challenges threatening individual and public health at home and abroad.

23 Sep 2019

Tanzania keeping Ebola under wraps

Ebola could be already on the prowl in Tanzania, but the government is keeping it a secret. This is the official position of the World Health Organization (WHO), who says multiple cases have been secretly reported to it.

23 Sep 2019

How one family counters epilepsy and caregiver stress by giving back

For people with epilepsy, seizures affect almost every aspect of their lives. The seizures also affect their caregivers' lives, with impacts on physical health, emotional functioning, social relationships, employment and finances.

23 Sep 2019

Conference reviews effects of tobacco products, underscores the importance of oral health

On September 14, 2018 AADR held the "Oral Health Effects of Tobacco Products: Science and Regulatory Policy" meeting in Bethesda, Maryland, USA.

23 Sep 2019

2019 ASTMH Annual Meeting to focus on Ebola, monkey malaria, and other infectious diseases

This year's meeting will kick off with keynotes from two public health heroes who have pioneered a home-based approach to fighting infant mortality in India that's now being adopted in 10 countries.

23 Sep 2019

African bacterium resists almost all drugs

It looks like it’s time to pay the piper. The first extensively drug-resistant (XDR) strain of Salmonella typhimurium, called ST313 sublineage II.1, has cropped up in the Democratic Republic of Congo (DRC). This fails to respond to any of the antibiotics that are commonly used in the DRC, except for ciprofloxacin. And to make things worse, one sample has been isolated that shows incomplete response even to this last drug.

22 Sep 2019

Faster, cheaper, better: improved gene therapy tool production

The heart of modern therapy is increasingly personalized and targeted at specific cellular or genetic deficits. This requires gene therapy, in many cases. A new study, published on 19 September 2019 in the journal Nature, describes an improved way to produce purified gene carrier viruses called AAVs cheaply and quickly, from the culture medium.

22 Sep 2019

New study identifies potential enzyme target for diabetic retinopathy

A new study shows that diabetic retinopathy (DR), or retinal disease caused by the high blood glucose levels in diabetes mellitus, is due to the death of retinal cells because of the high levels of a pro-enzyme called lysyl oxidase propeptide (LOX-PP). This could help researchers develop specific treatments by targeting this molecule.

22 Sep 2019

RNA hitches lysosome rides to make proteins far away from the nucleus

Proteins inside a cell are often made at the site where they are used, rather than being shipped long distances. This is so with nerve cells which have long cell extensions in the form of axons and dendrites, up to four feet long in some case

22 Sep 2019

Identification and management of depression in people with epilepsy to save lives

Depression is the most common psychiatric comorbidity in people with epilepsy. Clinical studies have found that 20% to 30% of people with epilepsy have depression; the incidence may be as high as 50% to 55% in people visiting hospital epilepsy centers.

21 Sep 2019

UTHealth's innovative cancer-fighting projects receive $11 million CPRIT funding

Five innovative cancer-fighting projects at The University of Texas Health Science Center at Houston received just over $11 million during the latest round of grants awarded by the Cancer Prevention and Research Institute of Texas

21 Sep 2019

Leukemia drug appears to be effective in treating deadly pediatric brain tumor

A drug used to treat chronic myeloid leukemia appears to be more effective at stopping a type of medulloblastoma in mouse models than existing treatments for the deadly pediatric brain tumor, reports a multi-institutional team led by researchers at Skaggs School of Pharmacy and Pharmaceutical Sciences at University of California San Diego.

21 Sep 2019

Researchers aim to explore effects of age, gender on brain injury mechanics

Traumatic brain injury and chronic traumatic encephalopathy have become common in athletes who suffer repeated blows to the head. Most recently, former New England Patriots tight end Rob Gronkowski revealed that he had sustained about 20 concussions during his nine-year career in the National Football League.

21 Sep 2019

Cutting-edge technologies to improve drug development while reducing animal testing

On Thursday, September 19th, 2019, the Physicians Committee for Responsible Medicine hosted a congressional briefing in cooperation with Rep. Brendan Boyle (D-Pa.), featuring innovator companies showcasing cutting-edge technologies that have the potential to improve the safety and efficacy of pharmaceuticals while reducing animal testing.

20 Sep 2019

Open Medicare data provides critical insights on hidden costs of health care

An interdisciplinary team of Indiana University scientists studying Medicare data have found an association between health care industry payments to medical providers for non-research expenses and what these providers charge for medical services -- shedding new light on potential hidden costs to the public.

20 Sep 2019

New clinical trial tests immunotherapy drug for prostate cancer patients on active surveillance

Stephenson Cancer Center Testing Drug for Prostate Cancer Patients on Active Surveillance OKLAHOMA CITY - Men who are diagnosed with low-risk prostate cancer usually opt for active surveillance - a monitoring of their cancer over time without undergoing treatments that would cause side effects.

20 Sep 2019

C-Path and NORD launch new platform to accelerate drug development for rare diseases

The Critical Path Institute and the National Organization for Rare Disorders® launched the Rare Disease Cures Accelerator-Data and Analytics Platform in Rockville, MD on Tuesday, Sept. 17.

20 Sep 2019

Mutations in specific protein make dengue virus resistant to vaccines and therapeutics

Dengue virus infects about 400 million people annually around the world, with a high prevalence in tropical and sub-tropical regions.

20 Sep 2019

SCAI's new shock classification scheme used to analyze patients in cardiac intensive care unit

A new shock classification scheme released by the Society for Cardiovascular Angiography and Interventions and endorsed by the American College of Cardiology, American Heart Association, the Society of Critical Care Medicine and the Society of Thoracic Surgeons was recently applied in a retrospective study analyzing patients in the cardiac intensive care unit at the Mayo Clinic.

20 Sep 2019

Research News and Research

Data on health-related quality of life often not collected for investigational cancer drugs

IDSA calls for meaningful funding to control current Ebola outbreak

Tanzania keeping Ebola under wraps

How one family counters epilepsy and caregiver stress by giving back

Conference reviews effects of tobacco products, underscores the importance of oral health

2019 ASTMH Annual Meeting to focus on Ebola, monkey malaria, and other infectious diseases

African bacterium resists almost all drugs

Faster, cheaper, better: improved gene therapy tool production

New study identifies potential enzyme target for diabetic retinopathy

RNA hitches lysosome rides to make proteins far away from the nucleus

Identification and management of depression in people with epilepsy to save lives

UTHealth's innovative cancer-fighting projects receive $11 million CPRIT funding

Leukemia drug appears to be effective in treating deadly pediatric brain tumor

Researchers aim to explore effects of age, gender on brain injury mechanics

Cutting-edge technologies to improve drug development while reducing animal testing

Open Medicare data provides critical insights on hidden costs of health care

New clinical trial tests immunotherapy drug for prostate cancer patients on active surveillance

C-Path and NORD launch new platform to accelerate drug development for rare diseases

Mutations in specific protein make dengue virus resistant to vaccines and therapeutics

SCAI's new shock classification scheme used to analyze patients in cardiac intensive care unit

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