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Childhood, adult obesity raise risk of developing hip and knee osteoarthritis

The results of a study to be presented at the Annual European Congress of Rheumatology suggest childhood and adult obesity increase the risk of developing hip osteoarthritis and knee OA but not hand OA.

18 Jun 2018

Study provides insights into genetics underlying debilitating pediatric kidney disease

New research provides insights into the genetics underlying a debilitating kidney disease in children. The findings, which appear in an upcoming issue of the Journal of the American Society of Nephrology, could lead to new diagnostics and, ultimately, treatments.

14 Jun 2018

Researchers discover genetic program that controls invasiveness of glioblastoma tumors

Glioblastoma is the most severe form of brain cancer in adults. The aggressiveness of this cancer is largely due to its ability to invade surrounding brain tissue, making the tumor difficult to remove by surgery.

14 Jun 2018

Scientists discover unique feature in the 'antennae' of light-sensing neurons

Scientists at Baylor College of Medicine and Radboud University Medical Center in the Netherlands have discovered that the antennae-like structures on light-sensing neurons, called photoreceptors, have a unique feature not observed in the 'antennae' or cilia of other types of cells.

14 Jun 2018

Scientists discover vaccine that may rapidly fight cholera-causing bacteria

A tricked-out cholera vaccine starts protecting against the deadly disease within a day, experiments in rabbits suggest.

14 Jun 2018

Extensive lipidomics studies reveal signatures of metabolic health and disease

Scientists from EPFL and the University of Wisconsin-Madison have carried out one of the most extensive lipidomics studies to date, connecting almost 150 different lipid species to their respective genetic regulators, revealing signatures of metabolic health and disease.

13 Jun 2018

OGT increases NGS cancer panel content to provide more flexibility for customization

Oxford Gene Technology, The Molecular Genetics Company, has expanded its SureSeq myPanel™ NGS Custom Cancer Panel content - now covering 120 fully optimized cancer related genes.

From Oxford Gene Technology 13 Jun 2018

New discovery could have significant implications in brain aging and cancers

Scientists at the University of Sheffield have discovered what keeps the perfect balance of breaks and repairs in our DNA - something which could help improve the success of chemotherapy and combat neurodegeneration associated with aging.

13 Jun 2018

Researchers discover genomic characteristics that define testicular germ cell cancer

Testicular germ cell cancer, a disease that is rare but growing in incidence in men in the United States, is considered to be among the most curable of solid tumors. Now researchers from the University of North Carolina Lineberger Comprehensive Cancer Center and a consortium of institutions have discovered the genetic and genomic characteristics that define the disease.

12 Jun 2018

Scientists discover first genetic marker for bone tumor

The first genetic marker for the bone tumor, osteoblastoma, has been discovered by scientists at the Wellcome Sanger Institute and their collaborators.

12 Jun 2018

IU researchers observe bacteria's 'DNA uptake' process

Indiana University scientists have made the first direct observation of a key step in the process that bacteria use to rapidly evolve new traits, including antibiotic resistance.

12 Jun 2018

Research identifies new genetic variations that could indicate higher prostate cancer risk

As the result of a six-year long research process, Fredrick R. Schumacher, PhD, a cancer epidemiology researcher at Case Western Reserve University School of Medicine, and an international team of more than 100 colleagues have identified 63 new genetic variations that could indicate higher risk of prostate cancer in men of European descent.

12 Jun 2018

Customising T-cells for cancer immunotherapy

T-cell immunotherapy is revolutionizing cancer treatments. CD8+ T cells are modified to recognize tumor-specific antigens and induce an immune response.

12 Jun 2018

Scientists find novel tactic with potential for fighting medulloblastoma

Scientists have a new tactic with potential for fighting medulloblastoma, the most common and most aggressive form of brain tumor in children. The results are scheduled for publication in Cancer Cell.

12 Jun 2018

Synthetic gene reveals potential therapeutic target for rare, inherited disease

DNA Repair is essential for a healthy organism. In every day of our lives, tens of thousands of damages occur in the genetic material of our cells. Hence, it is not surprising that a broad variety of repair mechanisms developed in the course of evolution that enables cells to quickly react and patch up the affected DNA strands.

11 Jun 2018

CRISPR-Cas9 technique may raise cancer risk

Therapeutic use of gene editing with the so-called CRISPR-Cas9 technique may inadvertently increase the risk of cancer, according to a new study from Karolinska Institutet, Sweden, and the University of Helsinki, Finland, published in Nature Medicine.

11 Jun 2018

Researchers isolate bacteria that pose triple threat from a patient in the U.S.

Researchers from the Emory Antibiotic Resistance Center describe the first strain of carbapenem-resistant, hypermucoviscous Klebsiella pneumoniae exhibiting colistin heteroresistance and enhanced virulence isolated from a patient in the United States.

11 Jun 2018