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Research from second pig heart transplant provides new directions for xenotransplantation

Continuing significant advancements in the field of xenotransplantation, surgeon-scientists from the University of Maryland School of Medicine provided an extensive analysis on the second patient in the world to receive a genetically-modified pig organ.

9 Jan 2025

Maternal medications linked to changes in protein and fat levels in human milk

The impact of maternal antidepressant and anti-inflammatory use on breast milk composition shows reduced protein and fat levels, affecting infant nutrition.

9 Jan 2025

Single-dose malaria vaccine offers unprecedented 90% protection

Results from the malaria vaccine trial indicate that GA2 immunization provides significant protection, paving the way for more effective vaccination strategies.

8 Jan 2025

AI-based method predicts progression of autoimmune diseases

Autoimmune diseases, where the immune system mistakenly attacks the body's own healthy cells and tissues, often have a preclinical stage before diagnosis that's characterized by mild symptoms or certain antibodies in the blood.

7 Jan 2025

Researchers develop nanobody inhibitors to target Ebola virus

Ebola virus, one of the deadliest pathogens, has a fatality rate of about 50%, posing a serious threat to global health and safety.

7 Jan 2025

Decades of research push cytomegalovirus vaccine closer to reality

Researchers review decades of progress in human cytomegalovirus (HCMV) vaccine development, emphasizing challenges, innovative platforms, and the critical need for effective prevention strategies.

6 Jan 2025

Scientists identify novel antibodies for fighting malaria

A novel class of antibodies that binds to a previously untargeted portion of the malaria parasite could lead to new prevention methods, according to a study from researchers at the National Institutes of Health (NIH) published today in Science.

3 Jan 2025

Breakthrough in immunology: AbMAP’s novel approach to antibody modeling

Researchers developed AbMAP, a cutting-edge framework leveraging transfer learning to model antibody hypervariable regions, significantly improving design and immune repertoire analysis.

2 Jan 2025

Blood cells linked to long-lasting vaccine immunity

When children receive their second measles-mumps-rubella vaccine, around the time they start kindergarten, they gain protection against all three viruses for all or most of their lives.

2 Jan 2025

Specialized bone marrow niches reveal secrets of immune tolerance

Researchers have uncovered a hierarchical structure of immune-privileged stem cells in bone marrow niches, revealing their regenerative potential and therapeutic relevance.

2 Jan 2025

Immunocompromised adults show weaker response to RSV vaccines

Johns Hopkins Medicine researchers have shown that people 60 years or older with weakened immunity - primarily organ transplant recipients who take immunosuppressive medications to reduce the risk of rejection and others with immune system disorders - do not respond as strongly to vaccines against the respiratory syncytial virus (RSV) as people in the same age group with normal immune function.

30 Dec 2024

Fruit flies steal bacterial defense to survive parasitic wasps

In the continual arms race between parasites and their hosts, innovation was thought to be the key to a successful attack or defense that one-ups the competition.

24 Dec 2024

WHO TAG-CO-VAC reviews COVID-19 vaccine effectiveness and antigen composition

The WHO Technical Advisory Group on COVID-19 Vaccine Composition (TAG-CO-VAC) continues to closely monitor the genetic and antigenic evolution of SARS-CoV-2 variants, immune responses to SARS-CoV-2 infection and COVID-19 vaccination, and the performance of COVID-19 vaccines against circulating variants.

24 Dec 2024

New Optimer contract to develop bioanalytical tools for RNA therapy

Aptamer Group plc, the developer of novel Optimer® binders to enable innovation in the life sciences industry, today announces the signing of a new development contract with a rare disease biopharmaceutical company.

From Aptamer Group 23 Dec 2024

Study uncovers how cancer builds molecular bridges to evade the immune system

"Build your enemy a golden bridge to retreat across" is a piece of advice offered by Sun Tzu in his ancient military treatise, The Art of War.

23 Dec 2024

Microglial cells may hold key to Alzheimer's plaque removal

Immune cells in the brain called microglia can partially break down large amyloid plaques characteristic of Alzheimer's disease by latching on to them, forming a sort of external stomach and releasing digestive enzymes into the space, according to a preclinical study by Weill Cornell Medicine investigators.

23 Dec 2024

UC Davis surgeon pioneers dual chamber leadless pacemaker in 13-year-old patient

UC Davis Director of Pediatric Electrophysiology Dan Cortez has set another world record: He is the first to implant a dual chamber leadless pacemaker in a child.

20 Dec 2024

New insights into respiratory syncytial virus and prevention strategies

Respiratory syncytial virus (RSV) is a major cause of respiratory infections, particularly in infants, children under 5 years, and older adults. Its rapid spread makes RSV a serious public health concern. Currently, there are no effective medications for RSV, and current treatment focuses on providing supportive care and preventing its spread.

20 Dec 2024

How America lost control of the bird flu, setting the stage for another pandemic

Keith Poulsen's jaw dropped when farmers showed him images on their cellphones at the World Dairy Expo in Wisconsin in October.

20 Dec 2024

Nogo-A inhibition demonstrates potential for spinal cord injury recovery

The latest study results have been published online in the renowned "The Lancet Neurology" journal. A multi-centre clinical trial (NISCI trial: Nogo-A Inhibition in acute Spinal Cord Injury Study) investigated the antibody NG 101 (anti-Nogo-A), which blocks and thus neutralizes the body's own Nogo-A protein.

19 Dec 2024