Central Nervous System News and Research

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Multivariate brain-wide associated studies can be replicable with substantially smaller sample sizes

Since the development of functional magnetic resonance imaging in the 1990s, the reliance on neuroimaging has skyrocketed as researchers investigate how fMRI data from the brain at rest, and anatomical brain structure itself, can be used to predict individual traits, such as depression, cognitive decline, and brain disorders.

16 Mar 2023

An overview of COVID-19-associated neurological complications in children

Researchers review current literature to understand the association between COVID-19, neuroimaging, and neurological symptoms in children.

14 Mar 2023

Study identifies link between oral and gut microbiomes and depression

Researchers investigate the role of the oral-gut-brain axis in anxiety and depression.

14 Mar 2023

Long-acting GIPRA inhibits feeding and lowers body weight in mice with diet-induced obesity

The hormone glucose-dependent insulinotropic polypeptide (GIP) is considered obesogenic. In contrast, GIP receptor agonists (GIPRAs) have shown reduced feeding and body weight in an obese mouse model. Therefore, the precise effects exerted by GIP and GIPRAs remain elusive.

14 Mar 2023

Hypothalamic inflammation and obesity, study suggests a pathological mechanism

In a recent review published in the European Journal of Endocrinology, researchers discussed current research on the relationship between human obesity and inflammation of the hypothalamus.

14 Mar 2023

Study reveals the shared genetic basis for endometriosis and other pain conditions

University of Queensland researchers have contributed to the largest ever genetic study of endometriosis, finding new data about the variants that increase risk of the disease.

13 Mar 2023

New tool allows researchers to perform genetic screens of cell-cell interactions

Inflammatory neurological diseases, such as multiple sclerosis (MS), can arise when cell-to-cell communication between cells in the central nervous system (CNS) goes awry.

13 Mar 2023

Abnormally low autoantibody activity significantly associated with autism severity

A recent study hypothesized a dysfunction of the self-recognition properties of the immune system in autism.

13 Mar 2023

How gut microbiota control feelings of fullness after eating

A recent study discusses recent findings linking satiety to the gut microbiome.

7 Mar 2023

Study finds two substances capable of inhibiting proliferation of glioblastoma cells

Glioblastoma is a malignant tumor of the central nervous system (brain or spinal cord) and one of the deadliest types of cancer.

7 Mar 2023

Researchers investigate the potential effect of folic acid supplementation on DNA mutation rates

It is well established that folic acid supplementation can significantly reduce the risk of birth defects, including neural tube defects like spina bifida, the most common birth defect of the central nervous system and the second most common of all structural birth defects.

6 Mar 2023

Analysis provides new insights into complex effects of Alzheimer’s disease on the retina

Cedars-Sinai investigators have produced the most extensive analysis to date of changes in the retina - a layer of tissue at the back of the eye where visual information originates - and how those retinal changes correspond to brain and cognitive changes in Alzheimer's disease patients.

3 Mar 2023

Researchers develop a potential treatment for autoimmune encephalitis

In autoimmune encephalitis, a rare but serious and sometimes life-threatening inflammation of the central nervous system, the body's own defenses are directed against the central nervous system.

3 Mar 2023

Biologists discover how to awaken and reactivate neural stem cells

Some areas of the adult brain contain quiescent, or dormant, neural stem cells that can potentially be reactivated to form new neurons.

1 Mar 2023

Bacteria exploit nerve cells in the meninges to facilitate brain invasion

A new study led by researchers at Harvard Medical School details the step-by-step cascade that allows bacteria to break through the brain's protective layers - the meninges - and cause brain infection, or meningitis, a highly fatal disease.

1 Mar 2023

More frequent cannabis use associated with higher risk of coronary artery disease

People who used marijuana daily were found to be about one-third more likely to develop coronary artery disease (CAD) compared with people who have never used the drug, according to a study presented at the American College of Cardiology's Annual Scientific Session Together With the World Congress of Cardiology.

24 Feb 2023

Exploring biodistribution of cannabidiol nanoparticles and nanoemulsion after intrathecal administration

Researchers evaluated the biodistribution of cannabidiol (CBD) emulsion and nanoparticles in the central nervous system (CNS).

24 Feb 2023

Does COVID-19 accelerate the worsening of clinical disabilities in multiple sclerosis patients?

The researchers investigated the impact of coronavirus disease 2019 (COVID-19) on the progression of clinical disability in multiple sclerosis patients.

24 Feb 2023

NQO2 gene as a novel potential target in Parkinson’s disease

A new study under review at the journal Scientific Reports and currently available on the Research Square* preprint server aimed to analyze the toxic effects of 6OHDA along with a related role of NQO2 in murine and human astrocytes.

23 Feb 2023

Research identifies potential treatment target for infantile spasms syndrome

New research from Tufts University School of Medicine and the Graduate School of Biomedical Sciences suggests that the timing of the death of certain inhibitory neurons in the brain shortly after birth may be at least partly to blame for infantile spasms syndrome (ISS), a rare but devastating form of epilepsy that develops most frequently between four and eight months of age but can emerge within weeks of birth until ages 4 or 5.

21 Feb 2023

Central Nervous System News and Research

Multivariate brain-wide associated studies can be replicable with substantially smaller sample sizes

An overview of COVID-19-associated neurological complications in children

Study identifies link between oral and gut microbiomes and depression

Long-acting GIPRA inhibits feeding and lowers body weight in mice with diet-induced obesity

Hypothalamic inflammation and obesity, study suggests a pathological mechanism

Study reveals the shared genetic basis for endometriosis and other pain conditions

New tool allows researchers to perform genetic screens of cell-cell interactions

Abnormally low autoantibody activity significantly associated with autism severity

How gut microbiota control feelings of fullness after eating

Study finds two substances capable of inhibiting proliferation of glioblastoma cells

Researchers investigate the potential effect of folic acid supplementation on DNA mutation rates

Analysis provides new insights into complex effects of Alzheimer’s disease on the retina

Researchers develop a potential treatment for autoimmune encephalitis

Biologists discover how to awaken and reactivate neural stem cells

Bacteria exploit nerve cells in the meninges to facilitate brain invasion

More frequent cannabis use associated with higher risk of coronary artery disease

Exploring biodistribution of cannabidiol nanoparticles and nanoemulsion after intrathecal administration

Does COVID-19 accelerate the worsening of clinical disabilities in multiple sclerosis patients?

NQO2 gene as a novel potential target in Parkinson’s disease

Research identifies potential treatment target for infantile spasms syndrome

Event guide: The 7th CNS Drug Delivery Summit eBook

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