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Molecular fingerprint predicts physical fitness in older adults

Could a simple blood test reveal how well someone is aging? A team of researchers led by Wolfram Weckwerth from the University of Vienna, Austria, and Nankai University, China, has combined advanced metabolomics with cutting-edge machine learning and a novel network modeling tool to uncover the key molecular processes underlying active aging.

30 Sep 2025

Genetic variant linked to liver injury after chemotherapy in colorectal cancer patients

A new international study led by Mayo Clinic researchers has identified a genetic factor that may explain why some patients with colorectal cancer that has spread to the liver experience more severe liver damage after chemotherapy.

29 Sep 2025

Herd immunity from HPV vaccine provides protection even for unvaccinated women

A large, long-term study led by an Albert Einstein College of Medicine researcher has found that the introduction of the human papillomavirus (HPV) vaccine in community settings is highly effective in protecting young women from infections caused by the cervical-cancer-causing virus-including women who didn't even receive the vaccine.

29 Sep 2025

Simple blood analysis can predict the risk of developing severe liver disease

A new study from Karolinska Institutet, published in the scientific journal The BMJ, shows how a simple blood analysis can predict the risk of developing severe liver disease.

29 Sep 2025

In hepatitis B vaccine debate, CDC panel sidesteps key exposure risk

The Trump administration is continuing its push to revise federal guidelines to delay the hepatitis B vaccine newborn dose for most children.

29 Sep 2025

Plant-based dog food cuts environmental impact by over 90% vs. red meat

Comparative research highlights the environmental benefits of plant-based dog food, showing reduced land use and emissions versus traditional meat-based diets.

29 Sep 2025

Novel biosensing platform provides quantitative graded evaluation of mild to severe liver injury

Real-time monitoring of key biomarkers is a critical prerequisite for early disease diagnosis and personalized therapy. Early detection of liver function impairment particularly relies on the measurement of serum alanine aminotransferase (ALT).

29 Sep 2025

Precision probiotics lower blood sugar and cholesterol in mice

Researchers developed a precision probiotic cocktail comprising three Lactobacillus strains that improved glucose control, reduced weight gain, and lowered cholesterol levels in mice fed a high-fat diet. Metabolomic and microbiome analyses revealed host metabolic adaptations and beneficial shifts in gut bacteria, highlighting translational potential for future clinical trials.

28 Sep 2025

Gut probiotic Christensenella tenuis reduces endotoxemia and improves metabolism in obese mice

This study is reported by the team of Professor Shuang-jiang Liu from Shandong University. The study reveals that the gut probiotic Christensenella tenuis significantly alleviates endotoxemia and metabolic disorders in a diet-induced obesity (DIO) mouse model by modulating gut bile acids (BAs) metabolism and suppressing lipopolysaccharide (LPS) translocation across the gut barrier.

26 Sep 2025

Study identifies key molecular and clinical biomarkers for MASLD

The causal biomarkers for metabolic dysfunction-associated steatotic liver disease (MASLD) and their clinical value remain unclear.

25 Sep 2025

Discovery of EP2 receptor opens path to pain relief without blocking inflammation

Scientists at the NYU Pain Research Center have identified which receptor in prostaglandins-the hormone-like substance targeted by common painkillers-causes pain but not inflammation.

25 Sep 2025

Targeting TGF-β signaling as a strategy to treat liver fibrosis

Liver fibrosis, a pathological scarring process resulting from chronic liver injury, represents a significant global health burden due to its potential progression to cirrhosis and hepatocellular carcinoma.

25 Sep 2025

Eating earlier in the day could help you lose more weight than later meals

Time-restricted eating impacts body composition and performance, with early eating linked to greater weight loss and late eating enhancing anaerobic power.

25 Sep 2025

Influenza infection in pregnant mice linked to fetal brain exposure

A new study from the University of Illinois Urbana-Champaign shows, for the first time, that severe flu infection in pregnant mice leads to a breakdown in placental and brain barriers, leading to the accumulation of potentially harmful molecules in the fetal brain.

24 Sep 2025

How food choices and cooking methods drive brain inflammation and disease

Researchers reviewing evidence in NeuroSci show how dietary AGEs and their interaction with RAGE drive oxidative stress, inflammation, and neurodegeneration. They highlight how cooking methods and diet choices could lower AGE burden and protect brain health, while calling for rigorous clinical trials.

24 Sep 2025

Scientists outline how future therapies could change type 1 diabetes care

Researchers writing in The Lancet review breakthroughs in type 1 diabetes treatment, from immunotherapies that delay onset to stem-cell β-cell replacement and automated insulin delivery. They stress that equitable access, validated surrogate endpoints, and scalable technologies are crucial for lasting impact.

24 Sep 2025

Fat distribution appears to influence cancer risk

How fat is distributed in people's bodies could make a difference to their risk of certain cancers, according to new research led by the University of Bristol. The international study is published in the Journal of the National Cancer Institute (JNCI) today [24 September].

23 Sep 2025

UCLA researchers identify proteins that guard the liver against damage during transplantation

In a mouse model of liver transplantation, UCLA researchers have identified proteins that act as "protective switches" guarding the liver against damage occurring when blood supply is restored during transplantation, a process known as ischemia-reperfusion injury.

23 Sep 2025

Alcohol-related mortality in the US surged 89% since 1999

A national study reveals a sharp rise in alcohol-induced deaths during COVID-19, with women and Native communities facing the greatest impact.

23 Sep 2025

Intravenous lactate raises pro-BDNF levels similar to high intensity workouts

Science has confirmed what sports lovers have always known from experience: exercise is good for the brain. It increases blood flow, inhibits stress hormones, and stimulates the release of 'feel good' endorphins.

23 Sep 2025