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VAI scientists uncover mechanism that annotates genetic information passed from fathers to offspring

Van Andel Institute scientists and collaborators have identified a key part of a mechanism that annotates genetic information before it is passed from fathers to their offspring.

7 Sep 2023

BA.2.86 Omicron variant: Is our immunity under siege?

A new preprint posted to the bioRxiv server discusses whether this variant shows neutralization escape.

7 Sep 2023

The impact of prolonged computer use on oculomotor function

Researchers conducted an evaluation of oculomotor function changes during prolonged computer usage using an eye tracker to collect data on eye movement at various intervals of screen time.

7 Sep 2023

Study characterizes SARS-CoV-2 Omicron BA.2.86: New variant under watch

Researchers identify a new SARS-CoV-2 variant, BA.2.86, with enhanced ability to evade immunity but lower infectivity compared to current variants. The study highlights the need for global monitoring due to its potential to become a predominant strain if it gains infectivity through mutations.

6 Sep 2023

Cozy images of plush toys and blankets counter messaging on safe infant sleep

Samuel Hanke is a pediatric cardiologist in Cincinnati, but when you ask him for his title, he follows it by saying: "Most importantly, I'm Charlie's dad."

6 Sep 2023

Review identifies future research directions for the study of a SARS-CoV-2 reservoir in PASC

Researchers reviewed the evidence for SARS-CoV-2 reservoir in post-acute sequelae of COVID-19 (PASC).

6 Sep 2023

Researchers characterize new SARS-CoV-2 BA.2.86 variant neutralization by monoclonal antibodies

Researchers used a SARS-CoV-2 spike protein-pseudotyped viral model to characterize BA.2.86 variant neutralization by monoclonal antibodies.

6 Sep 2023

Early viral exposure in mice weakens vaccine response, raising questions for human studies

Researchers at Washington University have demonstrated that early life exposure to multiple viruses in house mice dampens the immune response to SARS-CoV-2 vaccinations later in life. The study raises concerns about the applicability of common mouse models in immunological research, suggesting that prior pathogen exposure could be a significant variable in predicting vaccine efficacy.

5 Sep 2023

Monovalent vaccine outperforms bivalent in fighting new Omicron variants

New U.S. study finds mRNA-1273.815, a monovalent vaccine targeting the Omicron XBB.1.5 variant, generates higher neutralizing antibody titers compared to its bivalent counterpart. The study supports updating to an XBB.1.5-based monovalent vaccine for the 2023-24 campaign to combat emerging variants.

5 Sep 2023

Novavax's updated XBB.1.5 vaccine shows promising cross-neutralizing antibodies against new COVID-19 variants

The study reveals that Novavax's updated XBB.1.5 vaccine effectively induces cross-neutralizing antibodies against multiple Omicron XBB sub-variants in both mice and non-human primates.

5 Sep 2023

Aging reorganizes pancreas circadian transcriptome

A new research paper was published in Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science) Volume 15, Issue 16, entitled, "Reorganization of pancreas circadian transcriptome with aging."

5 Sep 2023

Can SARS-CoV-2 infect poultry?

New research in the Virology Journal suggests that chickens could become intermediate hosts for newly emerged SARS-CoV-2 variants, posing a potential threat to public health. The study identifies AXL and ACE2 receptors in chickens as likely binding sites for the virus, highlighting the need for further research and preventive measures.

5 Sep 2023

Gut feeling: How your microbiome could be shaping your mental health

Researchers in Biological Psychiatry delve into the complex relationship between the gut microbiome and mental health disorders like depression and bipolar disorder. The study explores how not just gut bacteria, but also lesser-known gut microorganisms such as viruses, fungi, and parasites, play a pivotal role in mood disorders.

5 Sep 2023

COVID-19 hits American Indian and Alaska Native populations hardest, new study reveals

A recent study at the University of New Mexico Hospital highlights that American Indian and Alaska Native populations face disproportionate severity and mortality rates from COVID-19. The research points to the urgent need for targeted interventions and resources to address these health disparities.

5 Sep 2023

New ARDS definition could expand diagnosis and treatment options

In a new report posted online in the American Journal of Respiratory and Critical Care Medicine, a global consensus conference of 32 critical care experts with broad international representation and from diverse backgrounds has proposed a new definition of acute respiratory distress syndrome (ARDS).

5 Sep 2023

Mutational changes in Avian flu virus could increase risk of transmission to humans

A new study from researchers in China and Nottingham has discovered that a subtype of avian flu virus, endemic in poultry farms in China, is undergoing mutational changes, which could increase the risk of the disease being passed on to humans.

5 Sep 2023

How SARS-CoV-2 hijacks Fragile X proteins to fuel infection: New clues in COVID-19 and genetic disorders

Study explores the interaction between SARS-CoV-2's non-structural protein 3 (NSP3) and proteins related to Fragile X mental retardation (FMRPs), shedding light on COVID-19 pathophysiology. The research suggests that the virus exploits these host cell proteins for effective infection and possibly interferes with antiviral defense mechanisms, offering new insights into the genetic basis of Fragile X syndrome.

5 Sep 2023

SARS-CoV-2 Eris variant spreads faster and dodges immunity

Study investigates the characteristics of the EG.5.1 "Eris" variant of SARS-CoV-2, finding it more transmissible among hamsters and slightly better at evading immunity compared to the XBB.1.5 variant. The results suggest that these properties could be driving the variant's increasing prevalence in human populations.

5 Sep 2023

Gut microbes play a starring role in insulin resistance, opening doors for new diabetes treatments

The study reveals a strong association between gut microbial carbohydrate metabolism and insulin resistance, pointing to gut microbes as a key player in metabolic syndrome and type 2 diabetes. Targeting these microbial activities could offer a new therapeutic pathway for improving insulin resistance and overall metabolic health.

4 Sep 2023

Pandemic pounds: Study reveals COVID-19's impact on pregnancy weight gain patterns

The study reveals that gestational weight gain (GWG) increased during the peak of the COVID-19 pandemic and plateaued in the later stages, affecting especially those who were overweight or obese. It highlights the influence of the pandemic on pregnancy-related outcomes, including pre-pregnancy weight and GWG.

4 Sep 2023

Syndrome News and Research

VAI scientists uncover mechanism that annotates genetic information passed from fathers to offspring

BA.2.86 Omicron variant: Is our immunity under siege?

The impact of prolonged computer use on oculomotor function

Study characterizes SARS-CoV-2 Omicron BA.2.86: New variant under watch

Cozy images of plush toys and blankets counter messaging on safe infant sleep

Review identifies future research directions for the study of a SARS-CoV-2 reservoir in PASC

Researchers characterize new SARS-CoV-2 BA.2.86 variant neutralization by monoclonal antibodies

Early viral exposure in mice weakens vaccine response, raising questions for human studies

Monovalent vaccine outperforms bivalent in fighting new Omicron variants

Novavax's updated XBB.1.5 vaccine shows promising cross-neutralizing antibodies against new COVID-19 variants

Aging reorganizes pancreas circadian transcriptome

Can SARS-CoV-2 infect poultry?

Gut feeling: How your microbiome could be shaping your mental health

COVID-19 hits American Indian and Alaska Native populations hardest, new study reveals

New ARDS definition could expand diagnosis and treatment options

Mutational changes in Avian flu virus could increase risk of transmission to humans

How SARS-CoV-2 hijacks Fragile X proteins to fuel infection: New clues in COVID-19 and genetic disorders

SARS-CoV-2 Eris variant spreads faster and dodges immunity

Gut microbes play a starring role in insulin resistance, opening doors for new diabetes treatments

Pandemic pounds: Study reveals COVID-19's impact on pregnancy weight gain patterns

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