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21-gene recurrence score can aid in radiation decision-making, shows study

A new study shows that a test physicians commonly used to guide chemotherapy treatment for post-breast cancer surgery patients may also help them decide whether radiation therapy may be of benefit.

10 Jan 2020

Sodium chloride nanoparticles offer potential for cancer therapies with fewer side effects

A new study at the University of Georgia has found a way to attack cancer cells that is potentially less harmful to the patient. Sodium chloride nanoparticles – more commonly known as salt – are toxic to cancer cells and offer the potential for therapies that have fewer negative side effects than current treatments.

9 Jan 2020

Common genetic defect in prostate cancer associated with worse prognosis

Like security screening to make sure nothing harmful makes its way into a crowded area, cells in the human body use checkpoints to control their growth and prevent harmful mutations from making their way into new cell populations and causing trouble.

9 Jan 2020

Nano-sized copper compounds together with immunotherapy can kill cancer cells

An interdisciplinary team of scientists from KU Leuven, the University of Bremen, the Leibniz Institute of Materials Engineering, and the University of Ioannina has succeeded in killing tumour cells in mice using nano-sized copper compounds together with immunotherapy. After the therapy, the cancer did not return.

9 Jan 2020

Asbestos exposure through cosmetic talc associated with mesothelioma

Thirty-three cases of the asbestos-related lung cancer mesothelioma draw attention to talcum powder as a non-occupational source of exposure to asbestos, according to a study in the January Journal of Occupational and Environmental Medicine.

9 Jan 2020

New method uses MRI, machine learning to forecast genetic mutations in glioma tumors

Researchers at Osaka University have developed a computer method that uses magnetic resonance imaging (MRI) and machine learning to rapidly forecast genetic mutations in glioma tumors, which occur in the brain or spine. The work may help glioma patients to receive more suitable treatment faster, giving better outcomes.

9 Jan 2020

Administering enzalutamide results in significant increase in PSMA density on tumor surface

When a non-scientist tries to imagine a scientist, the image that often arises is one of a somewhat remote, rather idealistic genius sitting alone in their room or laboratory and somehow discovering the most amazing things without every having contact with the 'normal' world.

9 Jan 2020

Surgical removal of tumor may boost survival of patients with brainstem high-grade gliomas

For adult patients with brainstem high-grade gliomas -- one of the rarest and deadliest forms of brain cancer -- surgically removing the entire tumor may add many months or potentially years of survival beyond that offered by radiation and chemotherapy, according to results of a medical records study led by researchers at the Johns Hopkins Kimmel Cancer Center.

From Johns Hopkins Medicine 9 Jan 2020

Study reveals cellular cross-talk between regulatory T cells and fibroblast cells in pancreatic cancer microenvironment

A multidisciplinary Michigan Medicine team is shedding new light on the role of regulatory T cells in pancreatic cancer - and, in mouse models, have uncovered a new potential target to improve immunotherapy approaches to the deadly disease.

9 Jan 2020

ToxPoint article highlights alternative mechanism to bring focus to major issues in toxicology

The new year has brought with it advances to the Society of Toxicology's official journal, Toxicological Sciences, some of which are reflected in the January 2020 issue - Volume 173, Issue 1.

9 Jan 2020

Pathios appoints Stuart Hughes as CEO and announces US$8.8M Series A financing round

Pathios Therapeutics Limited, an innovative biotech company focused on the development of first-in-class therapies for autoimmune diseases and cancer, today announced a US$8.8M Series A financing round with leading international healthcare investors Canaan and Australia’s Medical Research Commercialization Fund managed by Brandon Capital.

9 Jan 2020

Researchers identify new mechanism associated with p53 mutation

More than half of cancer cases worldwide are associated with genetic mutations in p53, the protein responsible for protecting DNA from changes that can lead to cancer.

9 Jan 2020

SVC112 molecule acts specifically against head and neck cancer stem cells

The red, tube-shaped flowers of the firecracker bush (Bouvardia ternifolia), native to Mexico and the American Southwest, attract hummingbirds.

8 Jan 2020

CU Cancer Center named National Pancreas Foundation Center of Excellence

The most important factor predicting the survival of pancreatic cancer patients is whether the cancer can be surgically removed (whether the cancer is "resectable").

8 Jan 2020

Scientists discover how dying cells prevent dangerous immune reactions

Dying cells in the body can keep the immune system in check, thus preventing unwanted immune responses against the body's own tissues.

8 Jan 2020

Study may provide novel targetable mechanisms of therapeutic resistance to anti-VEGF therapies

To establish a molecular signature of this resistance in ovarian cancer, the authors developed preclinical tumor models of adaptive resistance to chronic anti-VEGF treatment.

8 Jan 2020

Immune cells could help kill cancer cells, finds study

Researchers from UCL Cancer Institute have found that a subset of immune cells can kill cancer cells when activated.

8 Jan 2020

Pancreatic cancer cells release signal to suppress immune system's attack on tumors

A key immune signal has a previously unknown role in turning off the immune system's attack on pancreatic cancer cells, a new study finds.

8 Jan 2020

Biodegradable nanoparticle can deliver 'suicide gene' to pediatric brain tumor cells in mice

Johns Hopkins researchers report that a type of biodegradable, lab-engineered nanoparticle they fashioned can successfully deliver a "suicide gene" to pediatric brain tumor cells implanted in the brains of mice.

8 Jan 2020

Dog study suggests that AAV in gene therapy could induce cancer

A gene therapy study in dogs has stirred up old fears that by using AAV in gene therapy, it may be increasing cancer chances.

8 Jan 2020

Tumor News and Research

21-gene recurrence score can aid in radiation decision-making, shows study

Sodium chloride nanoparticles offer potential for cancer therapies with fewer side effects

Common genetic defect in prostate cancer associated with worse prognosis

Nano-sized copper compounds together with immunotherapy can kill cancer cells

Asbestos exposure through cosmetic talc associated with mesothelioma

New method uses MRI, machine learning to forecast genetic mutations in glioma tumors

Administering enzalutamide results in significant increase in PSMA density on tumor surface

Surgical removal of tumor may boost survival of patients with brainstem high-grade gliomas

Study reveals cellular cross-talk between regulatory T cells and fibroblast cells in pancreatic cancer microenvironment

ToxPoint article highlights alternative mechanism to bring focus to major issues in toxicology

Pathios appoints Stuart Hughes as CEO and announces US$8.8M Series A financing round

Researchers identify new mechanism associated with p53 mutation

SVC112 molecule acts specifically against head and neck cancer stem cells

CU Cancer Center named National Pancreas Foundation Center of Excellence

Scientists discover how dying cells prevent dangerous immune reactions

Study may provide novel targetable mechanisms of therapeutic resistance to anti-VEGF therapies

Immune cells could help kill cancer cells, finds study

Pancreatic cancer cells release signal to suppress immune system's attack on tumors

Biodegradable nanoparticle can deliver 'suicide gene' to pediatric brain tumor cells in mice

Dog study suggests that AAV in gene therapy could induce cancer

Industry Focus eBook - Cell & Gene Therapy (1st Edition) eBook

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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