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Anti-phospholipid antibodies in severely ill patients not distinctive to COVID-19, says study

A new study by researchers at the University of Toronto and the University of Calgary in Canada indicates that the presence of these antibodies correlates with more severe COVID-19 symptoms and signs.

25 Feb 2021

Neuroinvasiveness of SARS-CoV-2 shown by viral RNA and inflammation in the brain

A new study describes the results of a macaque study that showed the development of neurological features of inflammation, following infection by SARS-CoV-2.

25 Feb 2021

Researchers discover specific blood biomarker that predicts kidney transplant rejection

Researchers at the University of Pittsburgh School of Medicine have discovered a blood biomarker that predicts kidney transplant rejection with a lead time of about eight months, which could give doctors an opportunity to intervene and prevent permanent damage.

25 Feb 2021

'Miracle poison' can target a variety of different proteins

Researchers prove they can engineer proteins called proteases to find new targets with high selectivity, a critical advance toward potential new treatments for everything from neuro-regeneration to cytokine storm.

25 Feb 2021

CAR T-cell therapy produces deep, sustained remissions in patients with relapsed myeloma

In a major advance in the treatment of multiple myeloma, a CAR T-cell therapy has generated deep, sustained remissions in patients who had relapsed from several previous therapies, an international clinical trial has found.

24 Feb 2021

Tumors use unique mechanism to switch on regulatory T cells for protection

Immunologists at St. Jude Children's Research Hospital have discovered that tumors use a unique mechanism to switch on regulatory T cells to protect themselves from attack by the immune system.

24 Feb 2021

In Vivo Probes for Detecting Inflammation Markers in Humans and Animals

News-Medical talks to Parry Hashemi about research on in vivo probes for detecting inflammation markers in humans and animals she will present at Pittcon.

From Pittcon 24 Feb 2021

Study offers new insights into "Niemann-Pick type C disease"

In the journal Nature Communications, scientists of the German Center for Neurodegenerative Diseases (DZNE) report new findings on the mechanisms of "Niemann-Pick type C disease" (NPC).

24 Feb 2021

Corticosteroid receptor inhibitor shows anti-SARS-CoV-2 activity in vivo

A team of researchers examined PT150, which is an allosteric modulator of androgen and glucocorticoid receptors, to assess whether it had any antiviral activity or immunomodulatory activity to decrease the hyperinflammatory response of SARS-CoV-2 infection.

24 Feb 2021

Hyperactive immune system contributes to COVID-19 severity, lung damage

Researchers have pinpointed a helper T cell population in the lungs of patients with severe COVID-19 that may be central to the development of hyperinflammation, lung injury, and subsequent acute respiratory distress syndrome (ARDS) during disease.

24 Feb 2021

Slight differences can help distinguish between two similar pediatric brain conditions

Slight differences in clinical features can help physicians distinguish between two rare but similar forms of autoimmune brain inflammation in children, a new study by UT Southwestern scientists suggests.

23 Feb 2021

Study reveals new routes to potential treatments for chronic inflammatory conditions

Inflammatory lung diseases such as asthma, COPD and, most recently, COVID-19, have proven difficult to treat.

23 Feb 2021

Limiting the release of fat into the bloodstream during heart failure could help improve outcomes

University of Alberta researchers have found that limiting the amount of fat the body releases into the bloodstream from fat cells during heart failure could help improve outcomes for patients.

23 Feb 2021

Intentional cooling of the body may help improve acute respiratory distress syndrome

A tenth of all intensive care unit patients worldwide, and many critical patients with COVID-19, have acute respiratory distress syndrome (ARDS). Therapeutic hypothermia, an intentional cooling of the body, has been suggested as a way to improve ARDS.

23 Feb 2021

Study reveals a potential target for stroke treatment in blood-brain barrier

The blood-brain barrier prevents immune cells from circulating freely in the brain, and the breakdown of its function is a major cause of post-stroke inflammation.

23 Feb 2021

Cannabinoid receptor agonist shows potential protective effect on SARS-CoV-2-infected human heart cells

As scientists continue to search for effective antidotes to direct and indirect damage caused by the novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), a new preprint research paper posted to the bioRxiv* server demonstrates the potential of cannabinoid receptor agonists to alleviate myocardial damage in this condition even in the absence of any inhibitory effect on viral infection as such.

23 Feb 2021

Inflammation News and Research

Anti-phospholipid antibodies in severely ill patients not distinctive to COVID-19, says study

Neuroinvasiveness of SARS-CoV-2 shown by viral RNA and inflammation in the brain

Researchers discover specific blood biomarker that predicts kidney transplant rejection

'Miracle poison' can target a variety of different proteins

CAR T-cell therapy produces deep, sustained remissions in patients with relapsed myeloma

Tumors use unique mechanism to switch on regulatory T cells for protection

In Vivo Probes for Detecting Inflammation Markers in Humans and Animals

Study offers new insights into "Niemann-Pick type C disease"

Corticosteroid receptor inhibitor shows anti-SARS-CoV-2 activity in vivo

Hyperactive immune system contributes to COVID-19 severity, lung damage

Slight differences can help distinguish between two similar pediatric brain conditions

Study reveals new routes to potential treatments for chronic inflammatory conditions

Limiting the release of fat into the bloodstream during heart failure could help improve outcomes

Intentional cooling of the body may help improve acute respiratory distress syndrome

Study reveals a potential target for stroke treatment in blood-brain barrier

Cannabinoid receptor agonist shows potential protective effect on SARS-CoV-2-infected human heart cells

Universal strain of bacteria derived from healthy human skin can treat eczema

Study finds consistent neuroinflammatory response after intracerebral hemorrhage

Scientists find new therapeutic approach to effectively treat age-related macular degeneration

Some nutritional supplements may help prevent or mitigate COVID-19 severity

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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