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OHSU researchers confirm first-ever nonhuman primate model of Usher syndrome

Those with Usher Syndrome -- the leading hereditary cause for simultaneous deafness and blindness, for which there is no treatment -- may have a new reason for hope now that researchers have confirmed the first-ever nonhuman primate model of their disease.

13 Feb 2023

Behavioral deficits associated with chronic stress involve impaired neurosteroid synthesis and signaling

The latest generation of antidepressants relieves symptoms by mimicking steroids produced by the brain to ensure neurons are effectively talking to each other.

13 Feb 2023

New analytical platform quantifies the structure of mRNA-based medicines

Researchers from Tokyo Metropolitan University and RIKEN CSRS have developed a new analytical platform based on liquid chromatography, mass spectrometry and software analysis that quantifies the structure of messenger RNA (mRNA) based medicines.

13 Feb 2023

Ingestible sensor could offer an alternative to invasive procedures used to diagnose motility disorders

Engineers at MIT and Caltech have demonstrated an ingestible sensor whose location can be monitored as it moves through the digestive tract, an advance that could help doctors more easily diagnose gastrointestinal motility disorders such as constipation, gastroesophageal reflux disease, and gastroparesis.

13 Feb 2023

New method provides important insights into the development of epilepsy

In epilepsy research, it has long been assumed that a leaky blood-brain barrier is a cause of inflammation in the brain.

13 Feb 2023

New and surprising evidence that ChatGPT can perform several intricate tasks relevant to handling complex medical and clinical information

Researchers evaluated the performance of an AI model named ChatGPT to perform clinical reasoning on the United States Medical Licensing Exam (USMLE).

13 Feb 2023

MicroRNAs associated with diabetes in human pancreatic islets

In a recent study published in the Proceedings of the National Academy of Sciences, researchers explored micro-ribonucleic acids (RNAs) associated with diabetes and related characteristics in human pancreatic islets.

13 Feb 2023

Tecan collaborates with Singular Genomics to take automated NGS library preparation into the future

Tecan has partnered with Singular Genomics to use the turnkey MagicPrep™ NGS system* to create sequencing-ready libraries for the G4™ Sequencing Platform.

From Tecan 13 Feb 2023

Tecan collaborates with Element Biosciences to provide benchtop NGS

Tecan and Element Biosciences, Inc. – ¬¬ the developer of an innovative DNA sequencing platform disrupting genomics – are collaborating to offer a true benchtop NGS workflow with MagicPrep™ NGS* and the AVITI™ System.

From Tecan 13 Feb 2023

Vaccine efficacy and booster dose combinations among 18.9 million adults in the early phase of Omicron

A new study in the journal Clinical Infectious Diseases aimed to determine the relative vaccine effectiveness (rVE) in three different recipient cohorts, those who received the Ad26.COV2.S vaccine followed by Ad26.COV2.S booster, those who received the Ad26.COV2.S vaccine followed by an mRNA booster, and those who received two doses of an mRNA vaccine followed by an mRNA booster.

12 Feb 2023

Declining PSA levels predict improved survival rates in men with non-metastatic castration-resistant prostate cancer

Declines in prostate-specific antigen (PSA) level after treatment with the next-generation androgen receptor inhibitor drug enzalutamide predict improved survival rates in men with non-metastatic castration-resistant prostate cancer (nmCRPC), reports The Journal of Urology, an Official Journal of the American Urological Association.

10 Feb 2023

Research supports the role of strawberry consumption in promoting heart health

As attention focuses on heart disease this February for American Heart Month, the latest research on strawberries, including their potential heart health benefits, was presented at the 9th biennial Berry Health Benefits Symposium in Tampa, FL.

10 Feb 2023

Plasma D-dimer measurement can provide useful information when diagnosing periprosthetic joint infection

Measurement of plasma D-dimer levels – a test more commonly used to detect blood-clotting disorders – can provide useful information when making the difficult diagnosis of periprosthetic joint infection (PJI), reports a study in The Journal of Bone & Joint Surgery.

10 Feb 2023

Study identifies a previously unknown role of 'natural killer' immune cells

Melbourne researchers have improved our understanding of how the immune system is regulated to prevent disease, identifying a previously unknown role of 'natural killer' (NK) immune cells.

10 Feb 2023

High-precision mechanical sensing system can measure in vivo biomechanical properties of tissue, single cell

Fiber sensing scientists at Shenzhen University have developed a compact fiber optical nanomechanical probe (FONP) for measuring in vivo biomechanical properties of tissue and even single cell.

10 Feb 2023

Scientists identify miRNAs associated with type 2 diabetes in humans

MicroRNA (miRNA) molecules in pancreatic islets have been thought to play important roles in type 2 diabetes, but until now scientists have not confidently identified which miRNAs are associated with the disease in humans.

10 Feb 2023

β-damascone can function as an efficient modulator of dendritic cell-mediated functions

Dendritic cells (DCs) are important players of the immune system with important functions such as the identification of infectious pathogens, production of cytokines (chemical signalers of the immune system), presentation of antigens to activate T-cells, and more.

10 Feb 2023

Personalizing CAR-T cell stimulation during manufacturing can enhance its functionality

New adoptive T cell therapies - in which T cells, the immune system's natural hunters patrolling the body for foreign adversaries, are retrieved from cancer-riddled patients, super-charged and amplified outside the body, and then infused back into the same patient - are changing the prospects of cancer patients.

10 Feb 2023

Bread made from whole cell pulse flour simulates satiety hormones to help us feel full

Bread made from a new type of whole cell pulse flour can lower blood glucose (sugar) levels and keep you fuller for longer, new research has found.

10 Feb 2023

New method for capturing moments during protein translation

Nascent polypeptide chains or polypeptidyl-tRNAs (pep-tRNAs) occur transiently during protein synthesis. The potential to study these intermediates and better understand their role in processes like gene regulation has been greatly enhanced by the development of a process termed PETEOS—short for peptidyl-tRNA enrichment using organic extraction and silica adsorption.

10 Feb 2023

Technology News and Research

OHSU researchers confirm first-ever nonhuman primate model of Usher syndrome

Behavioral deficits associated with chronic stress involve impaired neurosteroid synthesis and signaling

New analytical platform quantifies the structure of mRNA-based medicines

Ingestible sensor could offer an alternative to invasive procedures used to diagnose motility disorders

New method provides important insights into the development of epilepsy

New and surprising evidence that ChatGPT can perform several intricate tasks relevant to handling complex medical and clinical information

MicroRNAs associated with diabetes in human pancreatic islets

Tecan collaborates with Singular Genomics to take automated NGS library preparation into the future

Tecan collaborates with Element Biosciences to provide benchtop NGS

Vaccine efficacy and booster dose combinations among 18.9 million adults in the early phase of Omicron

Declining PSA levels predict improved survival rates in men with non-metastatic castration-resistant prostate cancer

Research supports the role of strawberry consumption in promoting heart health

Plasma D-dimer measurement can provide useful information when diagnosing periprosthetic joint infection

Study identifies a previously unknown role of 'natural killer' immune cells

High-precision mechanical sensing system can measure in vivo biomechanical properties of tissue, single cell

Scientists identify miRNAs associated with type 2 diabetes in humans

β-damascone can function as an efficient modulator of dendritic cell-mediated functions

Personalizing CAR-T cell stimulation during manufacturing can enhance its functionality

Bread made from whole cell pulse flour simulates satiety hormones to help us feel full

New method for capturing moments during protein translation

Industry Focus eBook - Analytical Chemistry (2nd Edition) eBook

Expanding access to NMR with the Fourier 80 Duo

Advancing Intracellular Delivery with LumiPore®

How ELRIG Is Helping Mid-Career Scientists Navigate Leadership, Career Change and Redundancy

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