Physiology News and Research

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Human physiology is the science of the mechanical, physical, and biochemical functions of humans in good health, their organs, and the cells of which they are composed. The principal level of focus of physiology is at the level of organs and systems. Most aspects of human physiology are closely homologous to corresponding aspects of animal physiology, and animal experimentation has provided much of the foundation of physiological knowledge. Anatomy and physiology are closely related fields of study: anatomy, the study of form, and physiology, the study of function, are intrinsically tied and are studied in tandem as part of a medical curriculum.

For post-menopausal women light to moderate exercise is best

A British expert says that although exercise is important for reducing the risk of osteoporosis and heart disease in post-menopausal women, too much exercise in pre-menopausal women may actually increase the risks.

5 Sep 2005

Release of the neurotransmitter GABA halts stem cell production in the brain

Release of the neurotransmitter GABA by adult neuronal precursor cells that develop into neurons limits stem cell proliferation, according to a study at Yale School of Medicine in the September issue of Nature Neuroscience.

1 Sep 2005

Low doses of the active form of vitamin D and non-steroidal anti-inflammatory drugs form one-two punch against prostate cancer cells

Low doses of the active form of vitamin D and non-steroidal anti-inflammatory drugs, taken in combination, have been shown to act as a powerful one-two punch that knocks down the growth of prostate cancer cells.

1 Sep 2005

New drug CX717 can temporarily improve performance and reverse the effects of sleep deprivation

Research in monkeys suggests that a new drug can temporarily improve performance and reverse the effects of sleep deprivation on the brain, which would be a breakthrough in helping shift workers, health professionals, military personnel and others who must function at top performance in spite of sleep deficits.

23 Aug 2005

Rotenone study may lead to novel therapies for Parkinson's disease

Neuroscientists from the University at Buffalo have described for the first time how rotenone, an environmental toxin linked specifically to Parkinson's disease, selectively destroys the neurons that produce dopamine, the neurotransmitter critical to body movement and muscle control.

23 Aug 2005

SH2-B enhances brain's leptin sensitivity - may lead to clues for treatment of obesity and diabetes

What do laboratory mice at the University of Michigan Medical School have in common with millions of overweight Americans? Like many of us, these mice just can't stop eating.

18 Aug 2005

Gene therapy success for the treatment of congenital muscular dystrophy (CMD) in mice

Researchers from the University of Pittsburgh report the first study to achieve success with gene therapy for the treatment of congenital muscular dystrophy (CMD) in mice, demonstrating that the formidable scientific challenges that have cast doubt on gene therapy ever being feasible for children with muscular dystrophy can be overcome.

15 Aug 2005

How much people eat is in direct relation to how much they are served

If you binged for two weeks while on vacation and gained 5 pounds, would you be biologically primed to eat less to compensate and shake off the excess weight? No, suggests a new Cornell University study.

15 Aug 2005

Immune system more concerned with damage detected than foreign invaders, such as viruses

A well-respected researcher who is now a chief of an immunology laboratory of the National Institutes of Health (NIH) has rocked the boat in the past few years for the experts in the understanding of the autoimmune system.

15 Aug 2005

Oxytocin and ingestive behavior

More than 15 years ago Edward Stricker and Joseph Verbalis reported that oxytocin (OT) is involved in the neural control of food and salt intake in adult rats. Linda Rinaman at the University of Pittsburgh is investigating the anatomical organization of this system, and also is taking a developmental approach to determine how OT modulates eating and digestion.

11 Aug 2005

Findings could lead to gene therapy cure for childhood blindness

In findings that could lead to curing some forms of congenital blindness through gene therapy, researchers at UCLA have discovered that RPE65, a gene missing in infants born with the blinding disease Leber congenital amaurosis, is also a key enzyme in the visual cycle. The identity of this enzyme has long been a mystery to scientists.

11 Aug 2005

Protein that protects the body from tissue damage also increases the risk of tumors

You win some, you lose some. A protein that protects the body from tissue damage also increases the risk of tumors, according to a study conducted at Washington University School of Medicine in St. Louis. Moderate reduction of the protein level protects against tumor formation but increases susceptibility to tissue injury.

11 Aug 2005

Placental tissue could feasibly provide an abundant source of cells with the same potential to treat diseases as embryonic stem cells

Routinely discarded as medical waste, placental tissue could feasibly provide an abundant source of cells with the same potential to treat diseases and regenerate tissues as their more controversial counterparts, embryonic stem cells, suggests a University of Pittsburgh study to be published in the journal Stem Cells and available now as an early online publication in Stem Cells Express.

10 Aug 2005

Firefly protein lets researchers monitor molecule known as IKK (for IKappa kinase) linked to cancer

Scientists have used a glowing protein from fireflies to observe the activity of a molecule that is an important target for new drugs to treat cancer, autoimmune diseases and several other disorders.

9 Aug 2005

Study results reaffirm cyclin D1 as a candidate target for molecular therapeutic control of breast tumor development

For about a decade, scientists have recognized that many cases of hereditary breast cancer result from a mutation of a specific gene called BRCA1, which, in its normal state, helps keep tumor formation in check. About five to 10 percent of breast cancer cases arise from these genetic miscues, about half of which are linked to the abnormal functioning of BRCA1.

9 Aug 2005

Hot flashes - women experience this symptom differently

Hot flashes are well known to most menopausal women - and to many who are in perimenopause, the transition to menopause.

4 Aug 2005

Protein called cyclin D1 disrupts BRCA1's normal role as a cancer inhibitor

For about a decade, scientists have recognized that many cases of hereditary breast cancer result from a mutation of a specific gene called BRCA1, which, in its normal state, helps keep tumor formation in check. About five to 10 percent of breast cancer cases are linked to genetic miscues, about half of which are linked to BRCA1.

2 Aug 2005

Brain may interpret the information it receives from sensory neurons using a code more complicated than scientists previously thought

...according to new research from the National Autonomous University of Mexico and Cold Spring Harbor Laboratory. By studying how monkeys perceive a vibrating object when it touches the skin, scientists found that changes in an animal's attention over time influence how a sensory signal is interpreted.

1 Aug 2005

Link between peritoneum closure and fewer adhesions

A controversial surgical procedure that has lost favor among medical professionals may benefit women who have had caesarean sections. So say researchers at the Stanford University School of Medicine, who have found that closing the parietal peritoneum, a multi-layered membrane that lines the abdomino-pelvic walls, substantially decreases the likelihood of scarring that can make future C-sections more difficult.

1 Aug 2005

New research into muscle contraction will give scientists a better understanding of bladder problems and pain during childbirth

Professor Susan Wray, who heads the UK's top rated Department of Physiology, and Dr. Ted Burdyga, are studying muscles in the wall of the ureter, which connects the kidney to the bladder, to understand how muscles respond to signals in the body telling them to contract or relax.

1 Aug 2005

Physiology News and Research

For post-menopausal women light to moderate exercise is best

Release of the neurotransmitter GABA halts stem cell production in the brain

Low doses of the active form of vitamin D and non-steroidal anti-inflammatory drugs form one-two punch against prostate cancer cells

New drug CX717 can temporarily improve performance and reverse the effects of sleep deprivation

Rotenone study may lead to novel therapies for Parkinson's disease

SH2-B enhances brain's leptin sensitivity - may lead to clues for treatment of obesity and diabetes

Gene therapy success for the treatment of congenital muscular dystrophy (CMD) in mice

How much people eat is in direct relation to how much they are served

Immune system more concerned with damage detected than foreign invaders, such as viruses

Oxytocin and ingestive behavior

Findings could lead to gene therapy cure for childhood blindness

Protein that protects the body from tissue damage also increases the risk of tumors

Placental tissue could feasibly provide an abundant source of cells with the same potential to treat diseases as embryonic stem cells

Firefly protein lets researchers monitor molecule known as IKK (for IKappa kinase) linked to cancer

Study results reaffirm cyclin D1 as a candidate target for molecular therapeutic control of breast tumor development

Hot flashes - women experience this symptom differently

Protein called cyclin D1 disrupts BRCA1's normal role as a cancer inhibitor

Brain may interpret the information it receives from sensory neurons using a code more complicated than scientists previously thought

Link between peritoneum closure and fewer adhesions

New research into muscle contraction will give scientists a better understanding of bladder problems and pain during childbirth

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

The impact of vibration on microscopy

How Omics Technologies Are Transforming Biological Research and Drug Discovery

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